Antibodies to recombinant synaptotagmin and calcium channel subtypes in Lambert-Eaton myasthenic syndrome

Journal of the Neurological Sciences

Volumn 133, Issue 1-2, 1995, Pages 95-101

  Takamori, Masaharu ^a   Takahashi, Masami ^b   Yasukawa, Yoshihiro ^a   Iwasa, Kazuo ^a   Nemoto, Yasuo ^b   Suenaga, Akihito ^c   Nagataki, Shigenobu ^c   Nakamura, Tatsufumi ^c  

^a KANAZAWA UNIV SCHOOL OF MEDICINE   (Japan)

^b MITSUBISHI KASEI INST OF LIFE SCI   (Japan)

^c NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Acetylcholine; Calcium; Calcium channels; Lambert Eaton myasthenic syndrome; Muscle; Neuromuscular junction; Synaptotagmin

Indexed keywords

AUTOANTIBODY; CALCIUM CHANNEL; OMEGA CONOTOXIN; SYNAPTOTAGMIN;

ADULT; AGED; ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; EATON LAMBERT SYNDROME; FEMALE; HUMAN; IMMUNOBLOTTING; MALE; NEUROMUSCULAR SYNAPSE; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; AUTOANTIBODIES; CALCIUM CHANNELS; CARCINOMA, SMALL CELL; CELL DIFFERENTIATION; FEMALE; HUMAN; IMMUNOBLOTTING; ION CHANNEL GATING; LAMBERT-EATON MYASTHENIC SYNDROME; LUNG NEOPLASMS; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGE; NERVE TISSUE PROTEINS; PARANEOPLASTIC SYNDROMES; PRECIPITIN TESTS; RECOMBINANT PROTEINS; SUPPORT, NON-U.S. GOV'T;

EID: 0028894817     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-510X(95)00162-U     Document Type: Article

References (46)

1. Subunit structure and localization of dihydropyridine-sensitive calcium channels in mammalian brain, spinal cord, and retina
2. Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytosis
3. Synaptotagmin: a calcium sensor on the synaptic vesicle surface
4. The biochemistry and molecular biology of the dihydropyridine-sensitive calcium channel
5. Calcium-dependent interaction of the cytoplasmic region of synaptotagmin with membranes
6. Synaptotagmin V: a novel synaptotagmin isoform expressed in rat brain
7. Expression of synaptotagmin and syntaxin associated with N-type calcium channels in small cell lung cancer
8. Synaptotagmin II. A novel differentially distributed form of synaptotagmin
9. 2+ sensor for transmitter release at a central synapse
10. A third synaptotagmin gene, Syt3, in the mouse
11. Heterogeneity of calcium channel autoantibodies detected using a small-cell lung cancer line derived from a Lambert-Eaton myasthenic syndrome patient
12. IgG from patients with Lambert-Eaton syndrome blocks voltage-dependent calcium channels
13. Quantal components of end-plate potentials in the myasthenic syndrome
14. The effect of myasthenic syndrome antibody on presynaptic calcium channels in the mouse
15. 2+ flux in tumor cells correlates with disease severity
16. Autoantibodies bind solubilized calcium channel-ω-conotoxin complexes from small call lung carcinoma: a diagnostic aid for Lambert-Eaton myasthenic syndrome
17. 2+ channels
18. The synaptic vesicle protein synaptotagmin associates with calcium channels and is a putative Lambert-Eaton myasthenic syndrome antigen
19. Calcium channel autoantibodies in the Lambert-Eaton myasthenic syndrome
20. Immunoglobulins of Lambert-Eaton myasthenic syndrome inhibit rat pituitary hormone release
21. Exo-endocytotic recycling of synaptic vesicles in developing processes of cultured hippocampal neurons
22. Synaptotagmin III is a novel isoform of rat synaptotagmin expressed in endocrine and neuronal cells
23. An improved diagnostic assay for Lambert-Eaton myasthenic syndrome
24. Identification of protein receptor for Clostridium botulinum type B neurotoxin in rat brain synaptosomes
25. 2+ channel complex
26. Molecular diversity of neuronal type calcium channels identified in small cell lung carcinoma
27. The Lambert-Eaton myasthenic syndrome. A review of 50 cases
28. Selective action of myasthenic syndrome antibodies on calcium channels in a rodent neuroblastoma X glioma cell line
29. Structural and functional conservation of synaptotagmin (p65) in Drosophila and humans
30. Domain structure of synaptotagmin (p65)
31. Calcium channel β-subunit binds to conserved motif in the I–II cytoplasmic linker of the α1-subunit
32. 2+ channels in cerebellar granule
33. Molecular cloning of an Erwinia chrysanthemi oligogalacturonate lyase gene involved in pectin degradation
34. 2+ flux in a human small cell carcinoma line
35. Cloning and characterization of a Lambert-Eaton myasthenic syndrome antigen
36. Distinctive biophysical and pharmacological properties of class A (BI) calcium α1 subunit
37. Specificity of calcium channel autoantibodies in Lambert-Eaton myasthenic syndrome
38. Neurotransmitter release from synaptotagmin-deficient clonal variants of PC12 cells
39. Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of clonal genes
40. Proteins of synaptic vesicles involved in exocytosis and membrane recycling
41. Subunit structure of dihydropyridine-sensitive calcium channels from skeletal muscle
42. 2+/calmodulin-dependent protein kinase II phosphorylate a novel 58-kDa protein in synaptic vesicles
43. Synaptotagmin can cause an immune-mediated model of Lambert-Eaton myasthenic syndrome in rats
44. 2+ channels
45. The inhibitory effects of omega-conotoxins on Ca channels synapses