A pharmacogenetic basis for the safe and effective use of azathioprine and other thiopurine drugs in dermatologic patients

Journal of the American Academy of Dermatology

Volumn 32, Issue 1, 1995, Pages 114-116

  Snow, John L ^a   Gibson, Lawrence E ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 MERCAPTOPURINE DERIVATIVE; AZATHIOPRINE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MERCAPTOPURINE; THIOPURINE METHYLTRANSFERASE; TIOGUANINE; XANTHINE OXIDASE;

BONE MARROW TOXICITY; CYTOTOXICITY; DRUG EFFICACY; DRUG METABOLISM; DRUG SAFETY; ENZYME ACTIVITY; GENETIC POLYMORPHISM; HUMAN; IMMUNE DEFICIENCY; PHARMACOGENETICS; PRIORITY JOURNAL; REVIEW; SKIN DISEASE;

6-MERCAPTOPURINE; ALLELES; AZATHIOPRINE; ERYTHROCYTES; HETEROZYGOTE; HOMOZYGOTE; HUMAN; METHYLTRANSFERASES; POLYMORPHISM (GENETICS); SKIN DISEASES; SUPPORT, NON-U.S. GOV'T;

EID: 0028891465     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/0190-9622(95)90195-7     Document Type: Article

References (19)

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15. Pancytopenia related to azathioprine—an enzyme deficiency caused by a common genetic polymorphism: a review
16. The role of genetic variation in thiopurine methyltransferase activity and the efficacy and/or side effects of azathioprine therapy in dermatologic patients
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