Two-Metal Ion Mechanism of Bovine Lens Leucine Aminopeptidase: Active Site Solvent Structure and Binding Mode of L-Leucinal, a gem-Diolate Transition State Analogue, by X-ray Crystallography

Biochemistry

Volumn 34, Issue 45, 1995, Pages 14792-14800

  Sträter, Norbert ^a   Lipscomb, William N ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; ARGININE; BICARBONATE; CARBONYL DERIVATIVE; CYTOSOL AMINOPEPTIDASE; HYDROXYL GROUP; LEUCINAL; LYSINE; METAL ION; OXYGEN; SOLVENT; UNCLASSIFIED DRUG; ZINC;

ANIMAL TISSUE; ARTICLE; CATALYSIS; CATTLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME BINDING; HYDROGEN BOND; LENS; NONHUMAN; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

ANIMAL; BINDING SITES; CATTLE; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; LENS, CRYSTALLINE; LEUCINE; LEUCYL AMINOPEPTIDASE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEASE INHIBITORS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; WATER; ZINC;

ANIMALIA; BOS TAURUS; BOVINAE; SILO;

EID: 0028889561     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00045a021     Document Type: Article

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