Effect of matrix metalloproteinase inhibitor batimastat on breast cancer regrowth and metastasis in athymic mice

Journal of the National Cancer Institute

Volumn 87, Issue 20, 1995, Pages 1546-1551

  Sledge, George W ^a   Qulali, Mona ^b   Goulet, Robert ^c   Bone, Elisabeth A ^d   Fife, Rose ^b  

^a Indiana University School of Medicine   (United Kingdom)

^b Department of Medicine ^*  (United Kingdom)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d British Biotech Pharmaceuticals Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BATIMASTAT;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER GROWTH; CYTOTOXICITY; DRUG EFFECT; EXTRACELLULAR MATRIX; METASTASIS; MOUSE; NONHUMAN;

ANIMAL; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; CHI-SQUARE DISTRIBUTION; COLLAGENASES; FEMALE; HUMAN; LINEAR MODELS; LUNG NEOPLASMS; METALLOENDOPEPTIDASES; MICE; MICE, NUDE; NEOPLASM RECURRENCE, LOCAL; NEOPLASM TRANSPLANTATION; PHENYLALANINE; RNA, MESSENGER; RNA, NEOPLASM; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; THIOPHENES; TUMOR CELLS, CULTURED;

EID: 0028889359     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/87.20.1546     Document Type: Article

References (19)

1. Matrisian, LM. The matrix-degrading metalloproteinases. Bioessays 1992 14:455-63.
2. Liotta, LA. Tumor invasion and métastasés- role of the extracellular matrix: Rhoads Memorial Award lecture. Cancer Res 1986 46:1-7.
3. Liotta, LA, Rao, CN, Wewer UM. Biochemical interactions of tumor cells with the basement membrane. Annu Rev Biochem 1986 55:1037-57.
4. Liotta LA, Stetler-Stevenson WG, Steeg PS. Cancer invasion and metastasis: positive and negative regulatory elements. Cancer Invest 1991 9:543-51.
5. Liotta LA, Steeg PS, Stetler-Stevenson WG. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 1991 64:327-36.
6. Khokha R. Suppression of the tumorigenic and metastatic abilities of murine B16-F10 melanoma cells in vivo by the overexpression of the tissue inhibitor of the metalloproteinases-1. J Natl Cancer Inst 1994 86:299-304.
7. Dodwell DJ, Howell A. The potential for proteinase inhibition in cancer treatment. Can-cerTreatRev 1993 19:283-96.
8. Davies B, Brown PD, East N, Crimmin MJ, Balkwill FR. A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts [published erratum appears in Cancer Res 1993 53:3652]. Cancer Res 1993 53:2087-91.
9. Chirivi RG, Garofalo A, Crimmin MJ, Baw-den LJ, Stoppacciaro A, Brown PD, et al. Inhibition of the metastatic spread and growth of B16-BL6 murine melanoma by a synthetic matrix metalloproteinase inhibitor. Int J Cancer 1994 58:460-4.
10. Wang X, Fu X, Brown PD, Crimmin MJ, Hoffman RM. Matrix metalloproteinase inhibitor BB-94 (batimastat) inhibits human colon tumor growth and spread in a patientlike orthotopic model in nude mice. Cancer Res 1994 54:4726-8.
11. Fisher C, Gilbertson-Beadling S, Powers EA, Petzold G, Poorman R, Mitchell MA. Interstitial collagenase is required for angiogenesis in vitro. Dev Biol 1994 162:499-510.
12. Taraboletti G, Garofalo A, Belotti D, Drudis T, Borsotti P, Scanziani E, et al. Inhibition of angiogenesis and murine hemangioma growth by batimastat, a synthetic inhibitor of matrix metalloproteinases. J Natl Cancer Inst 1995 87:293-8.
13. Brown PD, Levy AT, Margulies IM, Liotta LA, Stetler-Stevenson WG. Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines. Cancer Res 1990 50:6184-91.
14. Price JE, Zhang RD. Studies of human breast cancer metastasis using nude mice. Cancer Metastasis Rev 1989 8:285-97.
15. Price JE, Polyzos A, Zhang RD, Daniels LM. Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice. Cancer Res 1990 50:717-21.
16. Price JE, Bell C, Frost P. The use of a genotypic marker to demonstrate clonal dominance during the growth and metastasis of a human breast carcinoma in nude mice. Int J Cancer 1990 45:968-71.
17. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987 162:156-9.
18. Qulali M, Ross RA, Crabb DW. Estradiol induces class I alcohol dehydrogenase activity and mRNA in kidney of female rats. Arch Biochem Biophys 1991 288:406-13.
19. Feinberg AP, Vogelstein B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 1983 132:6-13.