-
1
-
-
0025743216
-
Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice
-
USA
-
AGRAWAL, S., TEMSAMANI, J., and TANG, J.Y. (1991). Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice. Proc. Natl. Acad. Sci. USA 88, 7595-7599.
-
(1991)
Proc. Natl. Acad. Sci.
, vol.88
, pp. 7595-7599
-
-
AGRAWAL, S.1
TEMSAMANI, J.2
TANG, J.Y.3
-
2
-
-
0027056573
-
Enhanced rectal absorption and reduced local irritation of the anti-inflammatory drug ethyl 4-biphenylylacetate in rats by complexation with water-soluble beta cyclodextrin derivatives and formulation as oleaginous suppository
-
ARIMA, H., KONDO, T., IRIE, T., and UEKAMA, K. (1992). Enhanced rectal absorption and reduced local irritation of the anti-inflammatory drug ethyl 4-biphenylylacetate in rats by complexation with water-soluble beta cyclodextrin derivatives and formulation as oleaginous suppository. J. Pharm. Sci. 81, 1119-1125.
-
(1992)
J. Pharm. Sci.
, vol.81
, pp. 1119-1125
-
-
ARIMA, H.1
KONDO, T.2
IRIE, T.3
UEKAMA, K.4
-
3
-
-
0027758627
-
Introduction of antisense oligonucleotides into cells by permeabilization with streptolysin O
-
BARRY, E.L., GESEK, F.A., and FRIEDMAN, P.A. (1993). Introduction of antisense oligonucleotides into cells by permeabilization with streptolysin O. Biotechniques 15,1016-1018.
-
(1993)
Biotechniques
, vol.15
, pp. 1016-1018
-
-
BARRY, E.L.1
GESEK, F.A.2
FRIEDMAN, P.A.3
-
4
-
-
0027729703
-
Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: Initial results of a phase I trial
-
BAYEVER, E., IVERSEN, P., BISHOP, M., SHARP, G., TEWARY, H.K., ARNESON, M.A., PIRRUCCELLO, S.J., RUDDON, R.W., KESSINGER, A., ZOIN, G., and ARMITAGE, J.O. (1993). Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: Initial results of a phase I trial. Antisense Res. Dev. 3,383-390.
-
(1993)
Antisense Res. Dev.
, vol.3
, pp. 383-390
-
-
BAYEVER, E.1
IVERSEN, P.2
BISHOP, M.3
SHARP, G.4
TEWARY, H.K.5
ARNESON, M.A.6
PIRRUCCELLO, S.J.7
RUDDON, R.W.8
KESSINGER, A.9
ZOIN, G.10
ARMITAGE, J.O.11
-
6
-
-
0027759421
-
As nature intended? The uptake of DNA and oligonucleotides by eukaryotic cells [Review]
-
BENNETT. R.M. (1993). As nature intended? The uptake of DNA and oligonucleotides by eukaryotic cells [Review]. Antisense Res. Dev. 3,235-241.
-
(1993)
Antisense Res. Dev.
, vol.3
, pp. 235-241
-
-
BENNETT, R.M.1
-
7
-
-
0024444076
-
The potential use of cyclodextrins in parenteral formulations [Review]
-
231240.15.G.
-
BREWSTER, M.E., SIMPKINS, J.W., HORA, M.S., STERN, W.C., and BODOR, N. (1989). The potential use of cyclodextrins in parenteral formulations [Review]. J. Parent. Sci. Technol. 43, 231240.15.G.
-
(1989)
J. Parent. Sci. Technol.
, vol.43
-
-
BREWSTER, M.E.1
SIMPKINS, J.W.2
HORA, M.S.3
STERN, W.C.4
BODOR, N.5
-
8
-
-
0027935614
-
Adsorption of oligonucleotides onto polyisohexylcyanoacrylate nanoparticles protects them against nucleases and increases their cellular uptake
-
CHAVANY, C., SAISON-BEHMOARAS, T., DOAN, T.L., PUISIEUX, F., COUVREUR, P., and HELENE, C. (1994). Adsorption of oligonucleotides onto polyisohexylcyanoacrylate nanoparticles protects them against nucleases and increases their cellular uptake. Pharm. Res. 11, 1370-1378.
-
(1994)
Pharm. Res.
, vol.11
, pp. 1370-1378
-
-
CHAVANY, C.1
SAISON-BEHMOARAS, T.2
DOAN, T.L.3
PUISIEUX, F.4
COUVREUR, P.5
HELENE, C.6
-
9
-
-
0027417416
-
Delivery of antisense oligonucleotides by poly (1-lysine) conjugation and liposome encapsulation [Review]
-
CLARENC, J.P., DEGOLS, G., LEONETTI, J.P., MILHAUD, P., and LEBLEU, B. (1993). Delivery of antisense oligonucleotides by poly (1-lysine) conjugation and liposome encapsulation [Review]. Anti-Cancer Drug Design 8, 81-94.
-
(1993)
Anti-Cancer Drug Design
, vol.8
, pp. 81-94
-
-
CLARENC, J.P.1
DEGOLS, G.2
LEONETTI, J.P.3
MILHAUD, P.4
LEBLEU, B.5
-
10
-
-
0028183175
-
Pharmacokinetics of a relabeled phosphorothioate oligonucleotide, ISIS 2105, after intradermal administration to rats
-
COSSUM, P.A., TRUONG, L., OWENS, S R., MARKHAM, P.M., SHEA, J.P., and CROOKE, S.T. (1994). Pharmacokinetics of a relabeled phosphorothioate oligonucleotide, ISIS 2105, after intradermal administration to rats. J. Pharmacol. Exp. Ther. 269, 89-94.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.269
, pp. 89-94
-
-
COSSUM, P.A.1
TRUONG, L.2
OWENS, S.R.3
MARKHAM, P.M.4
SHEA, J.P.5
CROOKE, S.T.6
-
11
-
-
0025608105
-
The pharmacokinetics of beta-cyclodextrin and hydroxypropyl-beta-cyclodextrin in the rat
-
FRULINK, H.W., VISSER, J., HEITING, N.R., OOSTING, R., MEI-JER, D.K., and LERK, C.F. (1990). The pharmacokinetics of beta-cyclodextrin and hydroxypropyl-beta-cyclodextrin in the rat. Pharm. Res. 7,1248-1252.
-
(1990)
Pharm. Res.
, vol.7
, pp. 1248-1252
-
-
FRULINK, H.W.1
VISSER, J.2
HEITING, N.R.3
OOSTING, R.4
MEI-JER, D.K.5
LERK, C.F.6
-
12
-
-
0025305421
-
Slow-re-lease characteristics of diltiazem from ethylated beta-cyclodextrin complexes
-
HORIUCHI, Y., HIRAYAMA, F., and UEKAMA, K. (1990). Slow-re-lease characteristics of diltiazem from ethylated beta-cyclodextrin complexes. J. Pharm. Sci. 79,128-132.
-
(1990)
J. Pharm. Sci.
, vol.79
, pp. 128-132
-
-
HORIUCHI, Y.1
HIRAYAMA, F.2
UEKAMA, K.3
-
13
-
-
0026919380
-
Binding of antisense phosphorothioate oligonucleotides to murine lymphocytes is lineage specific and inducible
-
IVERSEN, P.L., CROUSE, D., ZON, G., and PERRY, G. (1992). Binding of antisense phosphorothioate oligonucleotides to murine lymphocytes is lineage specific and inducible. Antisense Res. Dev. 2, 223-233.
-
(1992)
Antisense Res. Dev.
, vol.2
, pp. 223-233
-
-
IVERSEN, P.L.1
CROUSE, D.2
ZON, G.3
PERRY, G.4
-
14
-
-
0025542154
-
Beta-cyclodextrins as vehicles in eye-drop formulations: An evaluation of their effects on rabbit corneal epithelium
-
JANSEN, T., XHONNEUX, B., MESENS, J., and BORGERS, M. (1990). Beta-cyclodextrins as vehicles in eye-drop formulations: An evaluation of their effects on rabbit corneal epithelium. Lens Eye Toxicity Res. 7,459-468.
-
(1990)
Lens Eye Toxicity Res.
, vol.7
, pp. 459-468
-
-
JANSEN, T.1
XHONNEUX, B.2
MESENS, J.3
BORGERS, M.4
-
15
-
-
0026877363
-
Liposomes as a drug delivery system for antisense oligonucleotides [Review]
-
JULLANO, R.L., and AKHTAR, S. (1992), Liposomes as a drug delivery system for antisense oligonucleotides [Review]. Antisense Res. Dev. 2, 165-176.
-
(1992)
Antisense Res. Dev.
, vol.2
, pp. 165-176
-
-
JULLANO, R.L.1
AKHTAR, S.2
-
16
-
-
0027473513
-
Modification of antisense phosphodiester oligodeoxynucleotides by a 5' cholesteryl moiety increases cellular association and improves efficacy
-
USA
-
KRIEG, A M., TONKINSON, J., MATSON, S., ZHAO, Q., SAXON, M., ZHANG, L.M., BHANJA, U.L., YAKUBOV, L., and STEIN, C.A. (1993). Modification of antisense phosphodiester oligodeoxynucleotides by a 5' cholesteryl moiety increases cellular association and improves efficacy. Proc. Natl. Acad. Sci. USA 90, 1048-1052.
-
(1993)
Proc. Natl. Acad. Sci.
, vol.90
, pp. 1048-1052
-
-
KRIEG, A.M.1
TONKINSON, J.2
MATSON, S.3
ZHAO, Q.4
SAXON, M.5
ZHANG, L.M.6
BHANJA, U.L.7
YAKUBOV, L.8
STEIN, C.A.9
-
17
-
-
0025798610
-
Intracellular distribution of microinjected antisense oligonucleotides
-
USA
-
LEONETTI, J.P., MECHTI, N., DEGOLS, G., GAGNOR, C., and LEBLEU, B. (1991). Intracellular distribution of microinjected antisense oligonucleotides. Proc. Natl. Acad. Sci. USA 88, 2702-2706.
-
(1991)
Proc. Natl. Acad. Sci.
, vol.88
, pp. 2702-2706
-
-
LEONETTI, J.P.1
MECHTI, N.2
DEGOLS, G.3
GAGNOR, C.4
LEBLEU, B.5
-
18
-
-
0025878065
-
Absorption enhancing effect of cyclodextrins on in-tranasally administered insulin in rats
-
MERKUS, F.W., VERHOEF, J.C., ROMEIJN, S.G., and SCHIPPER, N.G. (1991). Absorption enhancing effect of cyclodextrins on in-tranasally administered insulin in rats. Pharm. Res. 8,588-592.
-
(1991)
Pharm. Res.
, vol.8
, pp. 588-592
-
-
MERKUS, F.W.1
VERHOEF, J.C.2
ROMEIJN, S.G.3
SCHIPPER, N.G.4
-
19
-
-
0025814795
-
Enhanced cellular uptake of biotinylated antisense oligonucleotide or peptide mediated by avidin, a cationic protein
-
PARDRIDGE, W.M., and BOADO, R.J. (1991). Enhanced cellular uptake of biotinylated antisense oligonucleotide or peptide mediated by avidin, a cationic protein. FEBS Lett. 288,30-32.
-
(1991)
FEBS Lett.
, vol.288
, pp. 30-32
-
-
PARDRIDGE, W.M.1
BOADO, R.J.2
-
20
-
-
0026048443
-
Immunogenicity of immunoli-posomes
-
PHILLIPS, N.C., and EMILI, A. (1991). Immunogenicity of immunoli-posomes. Immunol. Lett. 30,291-296.
-
(1991)
Immunol. Lett.
, vol.30
, pp. 291-296
-
-
PHILLIPS, N.C.1
EMILI, A.2
-
21
-
-
0025335988
-
One-step labelling of oligonucleotides with fluorescein during automated synthesis
-
SCHUBERT, F., AHLERT, K., CECH, D., and ROSENTHAL, A. (1990). One-step labelling of oligonucleotides with fluorescein during automated synthesis. Nucleic Acids Res. 18,3427.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 3427
-
-
SCHUBERT, F.1
AHLERT, K.2
CECH, D.3
ROSENTHAL, A.4
-
22
-
-
0027376439
-
Antisense oligonucleotides as therapeutic agents—Is the bullet really magical? [Review]
-
STEIN, C.A., and CHENG, Y.C. (1993). Antisense oligonucleotides as therapeutic agents—Is the bullet really magical? [Review]. Science 261,1004-1012.
-
(1993)
Science
, vol.261
, pp. 1004-1012
-
-
STEIN, C.A.1
CHENG, Y.C.2
-
23
-
-
0025454391
-
Preparation of 35S-labeled polyphosphorothioate oligodeoxyribonucleotides by use of hydrogen phosphonate chemistry
-
STEIN, C.A., IVERSEN, P.L., SUBASINGHE, C., COHEN, J.S., STEC, W.J., and ZON, G. (1990). Preparation of 35S-labeled polyphosphorothioate oligodeoxyribonucleotides by use of hydrogen phosphonate chemistry. Anal. Biochem. 188,11-16.
-
(1990)
Anal. Biochem.
, vol.188
, pp. 11-16
-
-
STEIN, C.A.1
IVERSEN, P.L.2
SUBASINGHE, C.3
COHEN, J.S.4
STEC, W.J.5
ZON, G.6
-
24
-
-
0028025203
-
Cellular uptake of oligodeoxynucleotide phosphorothioates and their analogs
-
TEMSAMANI, J., KUBERT, M., TANG, J.Y., PADMAPRIYA, A., and AGRAWAL, S. (1994). Cellular uptake of oligodeoxynucleotide phosphorothioates and their analogs. Antisense Res. Dev. 4, 35-42.
-
(1994)
Antisense Res. Dev.
, vol.4
, pp. 35-42
-
-
TEMSAMANI, J.1
KUBERT, M.2
TANG, J.Y.3
PADMAPRIYA, A.4
AGRAWAL, S.5
-
25
-
-
0026661681
-
Synthetic cyclodextrin derivatives inhibit HIV infection in vitro
-
WEINER, D.B., WILLIAMS, W.V., WEISZ, P.B., and GREEN, M.I. (1992). Synthetic cyclodextrin derivatives inhibit HIV infection in vitro. Pathobiology 60,206-212.
-
(1992)
Pathobiology
, vol.60
, pp. 206-212
-
-
WEINER, D.B.1
WILLIAMS, W.V.2
WEISZ, P.B.3
GREEN, M.I.4
-
26
-
-
33748240878
-
Cyclodextrin as building blocks for supramolecular structures and functional units
-
WENZ, G. (1994). Cyclodextrin as building blocks for supramolecular structures and functional units. Angew. Chem. Int. Ed. Engl. 33, 803-822.
-
(1994)
Angew. Chem. Int. Ed. Engl.
, vol.33
, pp. 803-822
-
-
WENZ, G.1
-
27
-
-
0026838578
-
Lipofectin enhances cellular uptake of antisense DNA while inhibiting tumor cell growth
-
YEOMAN, L.C., DANELS, Y.J., and LYNCH, M.J. (1992). Lipofectin enhances cellular uptake of antisense DNA while inhibiting tumor cell growth. Antisense Res. Dev. 2,51-59.
-
(1992)
Antisense Res. Dev.
, vol.2
, pp. 51-59
-
-
YEOMAN, L.C.1
DANELS, Y.J.2
LYNCH, M.J.3
-
28
-
-
0028324788
-
Electron micrographic studies of transport of oligodeoxynucleotides across eukaryotic cell membranes
-
USA
-
ZAMECNIK, P., AGHAJANIAN, J., ZAMECNIK, M., GOODCHILD, J., and WITMAN, G. (1994). Electron micrographic studies of transport of oligodeoxynucleotides across eukaryotic cell membranes. Proc. Natl. Acad. Sci. USA 91,3156-3160.
-
(1994)
Proc. Natl. Acad. Sci.
, vol.91
, pp. 3156-3160
-
-
ZAMECNIK, P.1
AGHAJANIAN, J.2
ZAMECNIK, M.3
GOODCHILD, J.4
WITMAN, G.5
-
29
-
-
0029127845
-
Human pharmacokinetics of anti-HIV antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected individuals
-
ZHANG, R., SHAHINL\N, H., YAN, J., AMIN, G., LU, Z., JL-iNG, Z., TEMSAMANI, J., SAAG, M.S., SCHECHTER, P.S., AGRAWAL, S., and DIASIO, R.B. (1995). Human pharmacokinetics of anti-HIV antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected individuals. Clin. Pharmacol. Ther. 58,44-53.
-
(1995)
Clin. Pharmacol. Ther.
, vol.58
, pp. 44-53
-
-
ZHANG, R.1
SHAHINL\N, H.2
YAN, J.3
AMIN, G.4
LU, Z.5
JL-iNG, Z.6
TEMSAMANI, J.7
SAAG, M.S.8
SCHECHTER, P.S.9
AGRAWAL, S.10
DIASIO, R.B.11
-
30
-
-
0027325137
-
Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides
-
ZHAO, Q., MATSON, S., HERRERA. C.J., FISHER, E., YU, H., and KREIG, A.M. (1993). Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides. Antisense Res. Dev. 3,53-66.
-
(1993)
Antisense Res. Dev.
, vol.3
, pp. 53-66
-
-
ZHAO, Q.1
MATSON, S.2
HERRERA, C.J.3
FISHER, E.4
YU, H.5
KREIG, A.M.6
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