Identification of an endogenous inhibitor of prostatic carcinoma cell growth

Nature Medicine

Volumn 1, Issue 10, 1995, Pages 1040-1045

  Smith, Roy C ^a   Litwin, Mark S ^a,b   Lu, Yu ^a   Zetter, Bruce R ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGUANIDINE; PUTRESCINE; SPERMINE;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRATUMORAL DRUG ADMINISTRATION; MALE; PRIORITY JOURNAL; PROSTATE CARCINOMA; TUMOR;

ADENOCARCINOMA; ANIMAL; ENZYME INHIBITORS; GROWTH INHIBITORS; GUANIDINES; HUMAN; MALE; NEOPLASM INVASIVENESS; PROSTATE; PROSTATIC NEOPLASMS; PUTRESCINE; RATS; SPERMINE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TISSUE EXTRACTS; TUMOR CELLS, CULTURED;

EID: 0028884169     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1095-1040     Document Type: Article

References (29)

1. Boring, C.C., Squires, T.S., Tong, T. & Montgomery, S. Cancer statistics, 1994. CA: Cancer J. Clinicians 44, 7-26 (1994).
2. Scott, R. Jr, Mutchnik, D.L., Laskowski, T.Z. & Schmalhorst, W.R. Cancer of the prostate in elderly men: Incidence, growth characteristics and clinical significance. J. Urol 101, 602-607 (1969).
3. Stamey, T.A. et al. Localized prostate cancer. Relationship of tumor volume to clinical significance for treatment of prostate cancer. Cancer 71 (suppl. 3), 933-938 (1993).
4. McNeal, J.E. Prostatic microcarcinomas in relation to cancer origin and the evolution to clinical cancer. Cancer 71 (suppl. 3), 984-991 (1993).
5. Rossi, M.C. & Zetter, B.R. Selective stimulation of prostatic carcinoma cell proliferation by transferrin, Proc. natn. Acad. Sci. U.S.A. 89, 6197-6201 (1992).
6. Heston, W.D.W. Prostatic polyamines and polyamine targeting as a new approach to therapy of prostatic cancer. Cancer Surv. 11, 217-238 (1991).
7. Mann, T. Biochemistry of Semen and of the Male Reproductive Tract 193-200 (Wiley, New York, 1964).
8. Heby, O. & Andersson, G. Simplified micro-method for the quantitative analysis of putrescine, spermidine and spermine in the urine. J. Chromatogr. 145, 73-80 (1978).
9. Webber, M.M. & Chaproniere-Rickenberg, D. Spermine oxidation products are selectively toxic to fibroblasts in cultures of normal human prostatic epithelium. Ceil Biol int. Rep. 4, 185-193 (1980).
10. Allen, R.D. & Roberts, T.K. Role of spermine in the cytotoxic effects of seminal plasma. Am. J. repro. Immunol 13, 4-8 (1987).
11. Coffino, P. & Poznanski A. Killer polyamine? J. cell. Biochem. 45, 54-58 (1991).
12. Brunton, V.G., Grant, M.H. & Wallace H.M. Mechanisms of spermine toxicity in baby-hamster kidney (BHK) cells. The role of amine oxidases and oxidative stress. Biochem. J. 280, 193-198 (1991).
13. Kameji, T. & Pegg, A.E. Inhibition of translation of mRNAs for ornithine decarboxylase and S-adenosyìmethionine decarboxylase by polyamines. J. biol Chem. 262, 2427-2430 (1987).
14. Gahl, W.A. & Pitot, H.C. Reversal by aminoguanidine of the inhibition of proliferation of human fibroblasts by spermidine and spermine. Chem. Biol Interact. 22, 91-98 (1978).
15. Isaacs, J.T., Isaacs, W.B., Feitz, W.F. & Scheres, J. Establishment and characterization of seven Dunning rat prostatic cancer celllines and their use in developing methods for predicting metastatic abilities of prostatic cancers. Prostate 9, 261-281 (1986).
16. Chackal-Roy, M., Niemeyer, C., Moore, M. & Zetter, B.R, Stimulation of human prostatic carcinoma cell growth by factors present in human bone marrow. J. clin. Invest. 84, 43-50 (1989).
17. Celano, P., Baylin, S.B. & Casero, R. Jr. Polyamines differentially modulate the transcription of growth-associated genes in human colon carcinoma cells. J. biol Chem. 264, 8922-8927 (1989).
18. Pegg, A.E. Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy. Cancer Res. 48, 759-774 (1988).
19. Hibshoosh, H., Johnson, M. & Weinstein, I.B. Effects of overexpression of ornithine decarboxylase (ODC) on growth control and oncogene-induced cell transformation. Oncogene 6, 739-743 (1991).
20. Moshier, J.A., Dosescu, J., Skunca, M. & Luk, G.D. Transformation of NIH/3T3 cells by ornithine decarboxylase overexpression. Cancer Res. 53, 2618-2622 (1993).
21. Auvinen, M., Paasinen, A., Andersson, L.C. & Holtta, E. Ornithine decarboxylase activity is critical for cell transformation. Nature 360, 355-358 (1992).
22. Zaneveld, LJ.D. & Tauber, P.F. The Prostatic Cell: Structure and Function, Part A, 265-277 (Liss, New York, 1981).
23. Bernacki, R.J., Bergeron, R.J. & Porter, C.W. Antitumor activity of N, N’- bis(ethyl)spermine homologues against human MALME-3 melanoma xenografts. Cancer Res. 52, 2424-2430 (1992).
24. n-bis(ethyl)norspermine against human melanoma xenografts and possible biochemical correlates of drug action. Cancer Res. 53, 581-586 (1993).
25. 12-bis(ethyl)spermine. Cancer Res. 53, 2071-2075 (1993).
26. Danzin, C., Jung, M.J., Grove, J. & Bey, P. Effect of alpha-difluoromethylor-nithine, an enzyme-activated inhibitor of ornithine decarboxylase, on polyamine levels in rat tissues. Life Sci. 24, 519-524 (1979).
27. Janne, J., Raina A. & Sjimes, M. Spermidine and spermine in rat tissues at different ages. Acta physiol Scand. 62, 352-358 (1964).
28. Kabra, P.M., Lee, H.K., Lubich, W.P. & Morton, LJ. Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversed-phase liquid chromatography: improved separation systems for polyamines in cerebrospinal fluid, urine and tissue. J. Chromatogr. 380, 19-32 (1986).
29. Carmichael, J., DeGraff, W.G., Gazdar, A.F., Minna, J.D. & Mitchell, J.B. Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of hemo-sensitivity testing. Cancer Res. 47, 936-942 (1987).