Assessing bone quality - Animal models in preclinical osteoporosis research

Bone

Volumn 17, Issue 4 SUPPL., 1995, Pages

  Mosekilde, Li ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

NEW DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; BIOMECHANICS; BONE MASS; BONE REMODELING; CONFERENCE PAPER; DRUG EFFICACY; FEMUR NECK; LONG BONE; MORPHOMETRICS; NONHUMAN; OSTEOPOROSIS; RAT; VERTEBRA;

ANIMAL; BIOMECHANICS; BONE REMODELING; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; EVALUATION STUDIES; HUMAN; OSTEOPOROSIS; RATS; RESEARCH DESIGN; UNITED STATES;

EID: 0028883653     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/8756-3282(95)00312-2     Document Type: Article

References (36)

1. Effect of age on bone formation around orthopaedic implants.
2. On the rat model of human osteoporoses
3. Increased trabecular bone mass in rats treated with human synthetic parathyroid hormone
4. Gray's Anatomy
5. Human parathyroid hormone-(1–34) increases bone mass in ovariectomized and orchidectomized rats
6. 2 enhances cortical bone mass and activates intracortical bone remodeling in intact and ovariectomized female rats
7. Foreword: The aged rat model for bone biology studies
8. Bone functional changes in intact, ovariectomized, and ovariectomized, hormone-supplemented adult cynomolgus monkeys (Maca fascicularis) evaluated by serum markers and dynamic histomorphometry
9. Modulation of ovariectomy-related bone loss by parathyroid hormone in rats
10. The ovariectomized rat model of postmenopausal bone loss
11. Quantitative histologic changes in the proximal tibial growth cartilage of aged female rats
12. The effect of recombinant human (1–84) or synthetic human (1–34) parathyroid hormone on the skeleton of adult osteopenic ovariectomized rats
13. Human parathyroid hormone - (1–34) prevents bone loss and augments bone formation in sexually mature ovariectomized rats
14. Efficacy of risedronate for prevention of bone loss in the ovariectomized ferret
15. Compressive strength, ash weight, and volume of vertebral trabecular bone in experimental fluorosis in pigs
16. The effect of aging and ovariectomy on the vertebral bone mass and biomechanical properties of mature rats
17. Calcium restricted ovariectomized Sinclair S-1 Minipigs: An animal model of osteopenia and trabecular plate perforation
18. Normal age-related changes in bone mass, structure and strength - consequences of the remodeling process
19. The effect of long-term exercise on vertebral and femoral bone mass, dimensions and strength - assessed in a rat model
20. The effect on vertebral bone mass and strength of long term treatment with antiresorptive agents (Estrogen and Calcitonin), human parathyroid hormone-(1–38), and combination therapy, assessed in aged ovariectomized rats
21. Effects of two treatment regimes with synthetic human parathyroid hormone fragment on bone formation and the tissue balance of trabecular bone in greyhounds
22. Bone mechanical properties after exercise training in young and old rats
23. Sex differences in age-related remodeling of the femur and tibia
24. Effects of combined and separate intermittent administration of low dose human parathyroid hormone fragment (1–34) and 17β-estradiol on bone histomorphometry in ovariectomized rats with established osteopenia
25. Loss of cancellous bone mass and connectivity in ovariectomized rats can be restored by combined treatment with parathyroid hormone and estradiol
26. Marked decrease in trabecular bone quality after five years of sodium fluoride therapy — Assessed by biomechanical testing of iliac crest bone biopsies in osteoporotic patients
27. Long-term exercise of young and adult female rats: Effect on femoral neck biomechanical competence and bone structure
28. The positive effect of parathyroid hormone on femoral neck bone strength in ovariectomized rats is more pronounced than that of estrogen or bisphosphonates
29. Effects of fluoride on rat vertebral body biomechanical competence and bone mass
30. Effect of intermittent administration of human parathyroid hormone (1–34) on experimental osteopenia in rats induced by ovariectomy
31. Effects of 4-amino-1-Hydroxybutylidine biphosphonate on bone biomechanics in rats
32. Basic biomechanical measurements of bone: A tutorial
33. Changes induced in growing rat bone by immobilization and remobilization
34. Long-term effects of ovariectomy and aging on the rat skeleton
35. The ovariectomized rat as a model for postmenopausal bone loss