Effects of BMY21190, an inhibitor of cAMP phosphodiesterase, on infarct size and myeloperoxidase activity in the ischemic myocardium of a canine occlusion-reperfusion model

Pharmacology

Volumn 50, Issue 1, 1995, Pages 24-33

  Minami, Masaru ^a   Driscoll, Edward M ^b   Simpson, Paul J ^b   Hoff, Paul T ^b   Lucchesi, Benedict R ^b  

^a HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

BMY21190; cAMP phosphodiesterase; Canine occlusion; Infarct size; Inhibitor; Myeloperoxidase activity; Reperfusion model

Indexed keywords

7 (3 CYCLOHEXYLAZOXYPROPOXY)IMIDAZO[4,5 B]QUINOLIN 2(1H) ONE; CYCLIC AMP PHOSPHODIESTERASE; MYELOPEROXIDASE; PHOSPHODIESTERASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; DOG; DRUG EFFECT; DRUG STRUCTURE; ENZYME ACTIVITY; HEART HEMODYNAMICS; HEART INFARCTION SIZE; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; INTRAVENOUS DRUG ADMINISTRATION; LEFT CORONARY ARTERY; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMAL; DOGS; HEMODYNAMICS; IMIDAZOLES; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION; NEUTROPHIL ACTIVATION; PEROXIDASE; QUINOLINES;

EID: 0028883290     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000139263     Document Type: Article

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