Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate

Journal of Neuroscience

Volumn 15, Issue 10, 1995, Pages 6377-6388

  Dugan, L L ^a   Sensi, S L ^a   Canzoniero, L M T ^a   Handran, S D ^a   Rothman, S M ^a   Lin, T S ^b   Goldberg, M P ^a   Choi, D W ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

dihydrorhodamine; electron transport; excitotoxicity; free radicals; glutamate; mitochondria; neurotoxicity; oxidation

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; ARACHIDONIC ACID; ARGININE; CALCIUM; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; CITRININ; DIHYDRORHODAMINE 123; DIZOCILPINE; DYE; EGTAZIC ACID; GLUTAMIC ACID; IONOMYCIN; KAINIC ACID; MECLOFENAMIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE SYNTHASE INHIBITOR; OXYGEN RADICAL; POTASSIUM CHLORIDE; REACTIVE OXYGEN METABOLITE; RHODAMINE 123; ROTENONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; BRAIN CELL; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ELECTRON TRANSPORT; FETUS; FLUORESCENCE; MICROSCOPY; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 0028882764     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.15-10-06377.1995     Document Type: Article

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