P22 Arc Repressor: Transition State Properties Inferred from Mutational Effects on the Rates of Protein Unfolding and Refolding

Biochemistry

Volumn 34, Issue 42, 1995, Pages 13914-13919

  Milla, Marcos E ^a   Brown, Bronwen M ^a   Waldburger, Carey D ^a   Sauer, Robert T ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; GLYCINE; HYDROGEN; PROTEIN; SODIUM CHLORIDE;

AMINO ACID SUBSTITUTION; ARTICLE; DIMERIZATION; HYDROGEN BOND; MUTATION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; REPRESSOR GENE;

BACTERIOPHAGE P22; COMPUTER GRAPHICS; DNA-BINDING PROTEINS; HYDROGEN BONDING; KINETICS; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; REPRESSOR PROTEINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; UREA; VIRAL PROTEINS;

RUMEX;

EID: 0028882589     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00042a024     Document Type: Article

References (30)

1. Bowie, J. U., & Sauer, R. T. (1989a) Biochemistry 28, 7139-7143.
2. Bowie, J. U., & Sauer, R. T. (1989b) Proc. Natl. Acad. Sci. U.S.A. 86, 2152-2156.
3. Breg, J. N., Opheusden, J. H. J., Burgering, M. J. M., Boelens, R., & Kaptein, R. (1990) Nature 346, 586-589.
4. Brenstein, R. J. (1989) Robelko Software, version O.9 8b5, Carbondale, IL.
5. Brown, B. M., Milla, M. E., Smith, T. L., & Sauer, R. T. (1994) Nature Struct. Biol. 1, 164-168.
6. Creighton, T. E. (1992) BioEssays 15, 195-199.
7. Evans, P. A., & Radford, S. E. (1994) Curr. Opin. Struct. Biol. 4, 100-106.
8. Fersht, A. R. (1995) Curr. Opin. Struct. Biol. 5, 79-84.
9. Fersht, A. R., & Serrano, L. (1993) Curr. Opin. Struct. Biol. 3, 75-83.
10. Fersht, A. R., Matoushek, A., & Serrano, L. (1992) J. Mol. Biol. 224, 771-782.
11. Fersht, A. R., Itzhaki, L. S., ElMasry, N. F., Matthews, J. M., & Otzen, D. E. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 10426-10429.
12. Goldenberg, D. P. (1988) Annu. Rev. Biophys. Biophys. Chem. 17, 481-507.
13. Johnson, M., & Frasier, S. (1985) Methods Enzymol. 117, 301-342.
14. Kim, P. S., & Baldwin, R. L. (1990) Annu. Rev. Biochem. 59, 631-660.
15. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950.
16. Matouschek, A., & Fersht, A. R. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 7814-7818.
17. Matthews, C. R. (1993) Annu. Rev. Biochem. 62, 653-683.
18. Milla, M. E., & Sauer, R. T. (1994) Biochemistry 33, 1125-1133.
19. Milla, M. E., & Sauer, R. T. (1995) Biochemistry 34, 3344-3351.
20. Milla, M. E., Brown, B. M. & Sauer, R. T. (1993) Protein Sci. 2, 2198-2205.
21. Milla, M. E., Brown, B. M., & Sauer, R. T. (1994) Nature Struct. Biol. 1, 518-523.
22. Raumann, B. E., Rould, M. A., Pabo, C. O., & Sauer, R. T. (1994) Nature 367, 754-757.
23. Sauer, R. T., Krovatin, W., DeAnda, J., Youderian, P., & Susskind, M. (1983) J. Mol. Biol. 168, 699-713.
24. Schildbach, J. F., Milla, M. E., Jeffrey, P. D., Raumann, B. E., & Sauer, R. T. (1995) Biochemistry 34, 1405-1412.
25. Shortle, D. (1993) Curr. Opin. Struct. Biol. 3, 66-74.
26. Susskind, M. M., & Youderian, P. (1983) in Lambda II (Hendrix, R. W., Roberts, J. W., Stahl, F. W., & Weisberg, R. A., Eds.) pp 347-364, Cold Spring Harbor Laboratory, NY.
27. Tanford, C. (1970) Adv. Protein Chem. 24, 1-95.
28. Vershon, A. K., Youderian, P., Susskind, M. M., & Sauer, R. T. (1985) J. Biol. Chem. 260, 12124-12129.
29. Vershon, A. K., Bowie, J. U., Karplus, T. M., & Sauer, R. T. (1986) Proteins 1, 302-311.
30. Waldburger, C. D., Schildbach, J. F., & Sauer, R. T. (1995) Nature Struct. Biol. 2, 122-128.