Post-translationally modified 14-3-3 isoforms and inhibition of protein kinase C

Molecular and Cellular Biochemistry

Volumn 149-150, Issue 1, 1995, Pages 41-49

  Aitken, Alastair ^a   Howell, Steve ^a   Jones, David ^a   Madrazo, Joel ^a   Martin, Harry ^a   Patel, Yasmina ^a   Robinson, Karen ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

14 3 3 proteins; electrospray mass spectrometry; isoforms; kinase C; phosphorylation; post translational modifications

Indexed keywords

PROTEIN KINASE C;

CONFERENCE PAPER; HUMAN; NONHUMAN; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION;

AMINO ACID SEQUENCE; ANIMAL; CHICKENS; ENZYME INHIBITORS; HUMAN; MOLECULAR SEQUENCE DATA; PEPTIDES; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; SHEEP; SPECTRUM ANALYSIS, MASS; STRUCTURE-ACTIVITY RELATIONSHIP;

AVES; MAMMALIA;

EID: 0028881219     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/BF01076562     Document Type: Article

References (51)

1. The molecular heterogeneity of protein kinase C and its implications for cellular regulation
2. Inositol trisphosphate and calcium signalling
3. A protein kinase C inhibitory activity is present in rat brain homogenate
4. Inhibition by calmodulin of calcium/phospholipid-dependent protein phosphorylation
5. Ca2+-binding proteis from bovine brain including a potent inhibitor of protein kinase C
6. Purification of PKC-I, an endogenous protein kinase C inhibitor, and types 11 and lil protein kinase C isoenzymes from human neutrophus
7. Inhibition of protein kinase C by annexin V
8. Protein kinase C inhibitor proteins. Purification from sheep brain and sequence similarity to lipocortins and 14-3-3 protein
9. Multiple isoforms of a protein kinase C inhibitor (KCIP-1/14-3-3) from sheep brain: amino acid sequence of phosphorylated forms
10. Molecular cloning of cDNA coding for brain-specific 14-3-3 protein, a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases
11. 14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteins
12. Antibodies against the major isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino terminus of a protein
13. Complementary DNA cloning of a novel epithelial cell marker protein, HME1, that may be down-regulated in neoplastic mammary cells
14. Molecular cloning and expression of the transformation sensitive epithelial marker stratifin. A member of a protein family that has been involved in the protein kinase C signalling pathway
15. A plant homologue to mammalian brain kinase C inhibitor
16. A pathogen induced gene of barley encodes a protein showing high similarity to a protein kinase C regulator
17. Evolutionary implications of the family of 14-3-3 brain protein homologs in Arabidopsis thaliana
18. Characterization of a Droophila melanogaster gene similar to the mammalian genes encoding the tyrosine/tryptophan hydroxylase activator and protein kinase C inhibitor proteins
19. Evolutionary conservation of the 14-3-3 protein
20. Characterization of a yeast BMH 1 gene encoding a putative protein homologous to mammalian protein kinase 11 activators and protein kinase C inhibitors
21. 14-3-3 protein homologs required for the DNA damage checkpoint in fission yeast
22. Isolation and sequence analysis of a Caenorhabditis elegans cDNA which encodes a 14-3-3 homolog
23. Brain 14-3-3 protein is an activator protein that activates tryptophan 5-monooxygenase and tyrosine 3-monooxygenase in the presence of Ca2+, calmodulin-dependent protein kinase 11
24. Phosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen activated protein (MAP) kinase and MAP-kinase-activated kinases 1 and 2
25. Exol and Exo2 proteins stimulate calcium-dependent exocytosis in permeabilized adrenal chromaffin cells
26. Interaction between protein kinase C and Exol (14-3-3 protein) and its relevance to exocytosis in permeabilized adrenal chromaffin cells
27. Cloning and characterisation of the e and 4 isoforms of the 14-3-3 proteins
28. The eukaryotic host factor that activates exoenzyme S of Pseudomonas aeruginosa is a member of the 14-3-3 protein family
29. Cloning and expression of a human 14-3-3 protein mediating phospholipolysis
30. Association of polyoma middle tumor antigen with 14-3-3 proteins
31. 14-3-3: modulators of signaling proteins?
32. Multisite phosphorylation of the 80 kDa (MARCKS) protein kinase C substrate in C3H/10T1/2 fibroblasts
33. Purification of 14-3-3 protein and analysis of isoforms in chicken brain
34. Expression and structural analysis of 14-3-3 proteins
35. Primary structure of a human protein kinase regulator protein
36. Use of an on-line liquid chromatography trapping column for the purification of protein samples prior to electrospray mass spectrometric analysis
37. Glycogen synthase from rabbit skeletal muscle state of phosphorylation of the 7 phosphoserine residues in vivo in the presence and absence of adrenaline
38. The effects of phorbol esters with different biological activities on protein kinase C
39. Purification to homogeneity of protein kinase C from bovine brain — identity with the phorbol ester receptor
40. Subcellular distribution of 14-3-3 isoforms in rat brain using specific antibodies
41. Composition and synthesis during G1 and S phase of a high mobility group-E/G component from chinese hamster ovary cells
42. Mechanism of inhibition of protein kinase C by 14-3-3 isoforms
43. Characterisation of 14-3-3 proteins in adrenal chromaffin cells and demonstration of isoform-specific phospholipid binding
44. Structural elements for protein-phospholipid interactions may be shared in protein kinase C and phospholipases A2
45. Activation of protein kinase C by the 14-3-3 proteins homologous with Exol protein that stimulates calcium-dependent exocytosis
46. Kinase and neurotransmitters
47. Intracellular receptors for activated protein kinase C
48. Protein kinase C isoenzymes: divergence in signal transduction?