Screening for mitochondrial DNA (mtDNA) point mutations using nonradioactive single strand conformation polymorphism (SSCP) analysis

Clinical Biochemistry

Volumn 28, Issue 5, 1995, Pages 503-509

  Jaksch, M ^a   Gerbitz, K D ^a   Kilger, C ^b  

^a INSTITUT FÜR DIABETESFORSCHUNG   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

direct sequencing; heteroplasmy; LHON; MELAS; mitochondrial cytopathies; mtDNA; PCR SSCP; point mutations; polymorphisms; screening

Indexed keywords

MITOCHONDRIAL DNA;

ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; GENETIC SCREENING; HEREDITARY OPTIC ATROPHY; HUMAN; MELAS SYNDROME; MITOCHONDRIAL MYOPATHY; POINT MUTATION; PRIORITY JOURNAL; RELIABILITY; SINGLE STRAND CONFORMATION POLYMORPHISM;

BASE SEQUENCE; CLONING, MOLECULAR; DNA PRIMERS; DNA, MITOCHONDRIAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENETIC SCREENING; HUMAN; MITOCHONDRIAL ENCEPHALOMYOPATHIES; MOLECULAR SEQUENCE DATA; POINT MUTATION; POLYMORPHISM (GENETICS); POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; SEQUENCE DELETION; SUPPORT, NON-U.S. GOV'T;

EID: 0028879575     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/0009-9120(95)00035-8     Document Type: Review

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