The etiology and prediction of breast cancer. Fourier transform‐infrared spectroscopy reveals progressive alterations in breast DNA leading to a cancer‐like phenotype in a high proportion of normal women

Cancer

Volumn 75, Issue 2, 1995, Pages 503-517

  Malins, Donald C ^a   Polissar, Nayak L ^a   Nishikida, Koichi ^b   Holmes, Eric H ^c   Gardner, Henry S ^d   Gunselman, Sandra J ^a  

^a PACIFIC NORTHWEST RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c PERKINELMER INC   (United States)

^d U S ARMY MEDICAL RESEARCH AND MATERIEL COMMAND   (United States)

Author keywords

breast cancer; cancer etiology; cancer predictors; DNA base damage; free radicals; gas chromatography mass spectrometry; hydroxyl radical; infrared spectroscopy; modified nucleotide bases; premalignant cancer markers

Indexed keywords

DNA; HYDROXYL RADICAL;

ARTICLE; BREAST CANCER; CANCER RISK; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA DETERMINATION; DNA STRUCTURE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INFRARED SPECTROSCOPY; INTRADUCTAL CARCINOMA; PHENOTYPE; PRECANCER; PREDICTION; PRIORITY JOURNAL; STATISTICAL MODEL;

BREAST; BREAST NEOPLASMS; CARCINOMA, INFILTRATING DUCT; COMPARATIVE STUDY; DNA, NEOPLASM; FACTOR ANALYSIS, STATISTICAL; FEMALE; HUMAN; MODELS, BIOLOGICAL; PRECANCEROUS CONDITIONS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SUPPORT, U.S. GOV'T, NON-P.H.S.;

EID: 0028878307     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/1097-0142(19950115)75:2<503::AID-CNCR2820750213>3.0.CO;2-0     Document Type: Article

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