Alterations in carbohydrate metabolism during stress: A review of the literature

The American Journal of Medicine

Volumn 98, Issue 1, 1995, Pages 75-84

  Mizock, Barry A ^a  

^a ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BURN; CARBOHYDRATE METABOLISM; DIET SUPPLEMENTATION; GLUCONEOGENESIS; GLUCOSE INTOLERANCE; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; GLYCOGEN SYNTHESIS; HUMAN; HYPERLACTATEMIA; HYPERMETABOLISM; INJURY; INSULIN RESISTANCE; METABOLIC REGULATION; PRIORITY JOURNAL; REVIEW; SEPSIS; STRESS;

ANIMAL; GLUCONEOGENESIS; GLUCOSE; HUMAN; INSULIN RESISTANCE; STRESS;

EID: 0028878281     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9343(99)80083-7     Document Type: Review

References (107)

1. Management of diabetes in the critically ill patient
2. Multiple organ failure syndrome
3. Hypermetabolism, organ failure, and metabolic support
4. Metabolism after trauma and in sepsis
5. The wound as an organ
6. Contribution of different organs to increased glucose consumption after endotoxin administration.
7. Gram-negative infection increases noninsulin-mediated glucose disposal
8. Mammalian facilitative glucose transporter family: structure and molecular regulation
9. The biology and biochemistry of the glucose transporter
10. Molecular biology of mammalian glucose transporters
11. Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell
12. Hormonal regulation of mammalian glucose transport
13. Regulation of insulin-stimulated glucose transport in the isolated rat adipocyte
14. Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans.
15. Noninvasive determination of local cerebral metabolic rate of glucose in man
16. Differential regulation of glucose transporter gene expression in adipose tissue of septic rats
17. Sepsis-induced increases in glucose uptake by macrophage-rich tissues persist during hypoglycemia
18. Insulin-like activity (ILA) of a macrophage mediator on adipose tissue glucose oxidation
19. Effect of endotoxin-induced monokines on glucose metabolism in the muscle cell line L6
20. Tumor necrosis factor enhances glucose uptake by peripheral tissues.
21. Tumor necrosis factor increases in vivo glucose utilization of macrophage-rich tissues
22. Cellular stress induces a redistribution of the glucose transporter
23. Regulation of glucose uptake by stressed cells
24. Interleukin-1 stimulates hexose transport in fibroblasts by increasing the expression of glucose transporters
25. Monokine regulation of glucose transporter mRNA in L6 myotubes
26. Altered glucose transporter mRNA abundance in a rat model of endotoxic shock
27. Glucose transporters (GLUT1, 2, −4) in fat muscle, and liver in a rat model of endotoxic shock
28. Supply dependency of oxygen uptake in ARDS: myth or reality
29. Defective oxidative metabolism of rat mitochondria in hemorrhagic and endotoxin shock
30. 18F]fluoromisonidazole
31. Sepsis alters skeletal muscle energetics and membrane function
32. 31P NMR in vivo. III. Alterations of muscle blood flow and metabolism during sepsis
33. Sepsis does not impair tricarboxylic acid cycle in the heart
34. 31P-NMR spectroscopy
35. Reevaluation of the role of cellular hypoxia and bioenergetic failure in sepsis
36. Isotopic evaluation of the metabolism of pyruvate and related substrates in normal adult volunteers and severely burned children: effect of dichloroacetate and glucose infusion
37. The syndrome of hypermetabolism and multiple system organ failure
38. Lactate production under fully aerobic conditions: the lactate shuttle during rest and exercise
39. Can lactate be used as a fuel by wounded tissue?
40. Why does brain make lactate?
41. Myocardial substrate utilization in dogs following endotoxin administration
42. Energy metabolism and proteolysis in traumatized and septic man
43. Glucose metabolism in severely burned patients
44. The effect of sepsis on the oxidation of carbohydrate and fat
45. Physiological and metabolic correlations in human sepsis
46. Correlations between metabolic and cardiopulmonary measurement in patients after trauma, general surgery and sepsis
47. Lactic acidosis
48. Metabolic effects of partial reversal of pyruvate dehydrogenase activity by dichloroacetate in sepsis
49. Glucose kinetics in rats infused with endotoxin-induced monokines or tumor necrosis factor
50. Effect of glucose infusion on glucose and lactate metabolism in normal and burned guinea pigs
51. Carbohydrate metabolism in man: effect of elective operations and major injury
52. Regulation of the pyruvate dehydrogenase multienzyme complex
53. Fuel selection in animals
54. Regulation of glucose metabolism by altered pyruvate dehydrogenase activity. I. Potential site of insulin resistance in sepsis
55. Increased pyruvate dehydrogenase kinase activity in response to sepsis
56. Pharmacological reversal of abnormal glucose regulation, BCAA utilization, and muscle catabolism in sepsis by dichloroacetate
57. Glucose kinetics and pyruvate dehydrogenase activity in septic rats treated with dichloroacetate
58. Lactate metabolism
59. The significance of altered gluconeogenesis in surgical catabolism
60. The glucose-alanine cycle
61. The origin of alanine produced in skeletal muscle
62. Alanine: key role in gluconeogenesis
63. Branched chain amino acids as a major source of alanine nitrogen in man
64. Glycerol turnover and oxidation in man
65. The effect of hemorrhagic stress on liver gluconeogenesis
66. Carbohydrate metabolism in the critically ill patient
67. Somatostatin infusion inhibits glucose production in burn patients
68. Glucose and lactate metabolism in experimental septic shock
69. Alterations in Lipid and Carbohydrate Metabolism in Sepsis
70. The glucose-alanine cycle: origin of control
71. Stimulatory effect of interleukin-1 upon hepatic metabolism
72. Glucose dyshomeostasis in endotoxicosis: direct versus monokine-mediated mechanisms of endotoxin action
73. Effect of injury and infection on visceral metabolism and circulation
74. Effects of adrenergic blockade on glucose kinetics in septic and burned guinea pigs
75. Hepatocyte-Kupffer cell interactions in the inhibition of hepatic gluconeogenesis by bacterial endotoxin
76. Sepsis-induced alterations in phosphoenolpyruvate carboxykinase expression: the role of insulin and glucagon
77. Altered transcriptional regulation of phospho-enolpyruvate carboxykinase in rats following endotoxin treatment
78. Hypoglycemia, hormones and cytokines in fatal meningococcal septicemia
79. Hypoglycemia as a manifestation of sepsis
80. Hypoglycemia: a common complication of septicemia in cirrhosis
81. Hypoglycemia and sepsis in two elderly diabetics
82. Studies on the mechanism by which exogenous glucose is converted into liver glycogen in the rat
83. Glucose load diverts hepatic gluconeogenic product from glucose to glycogen in vivo
84. The contribution of gluconeogenesis to glycogen repletion during glucose infusion in endotoxemia
85. Mechanisms of hepatic and peripheral insulin resistance during acute infections in humans
86. Glucose metabolism in man: response to intravenous glucose infusion
87. Dose-response characteristics for effects of insulin on production and utilization of glucose in man
88. Mechanisms of insulin resistance in human obesity
89. Insulin resistance and depressed gluconeogenic capability during early hyperdynamic sepsis
90. Spitzer JA: Insulin action and binding in adipocytes exposed to endotoxin in vitro and in vivo
91. Myocardial insulin resistance during acute endotoxin shock in dogs
92. Sepsis inhibits insulin-stimulated glucose transport in isolated rat adipocytes
93. Insulin-mediated glucose uptake by individual tissues during sepsis
94. Differentiation between septic and postburn insulin resistance
95. Evidence that glucose transport is rate-limiting for in vivo glucose uptake
96. Localization of Rate-Limiting Defect for Glucose Disposal in Skeletal Muscle of Insulin-Resistant Type I Diabetic Patients
97. In vitro insulin resistance of human adipocytes isolated from subjects with noninsulin-dependent diabetes mellitus
98. Rate-limiting steps for insulin-mediated glucose uptake into perfused rat hindlimb.
99. Reduced glucose oxidation and pyruvate-dehydrogenase activity (PDH) in type I diabetics (insulin-dependent) in poor control
100. Correlation between muscle glycogen synthase activity and in vivo insulin action in man
101. Influence of dietary carbohydrate on skeletal muscle glucose uptake
102. Muscle glucose metabolism following exercise in the rat
103. Intracellular glucose concentration in small and large rat adipose cells
104. Sepsis
105. Metabolic response to burn injury: nutritional implications
106. Insulin-stimulated translocation of glucose transport systems in the isolated rat adipose cell