The POU homeodomain transcription factor Oct-1 is essential for activity of the gonadotropin-releasing hormone neuron-specific enhancer

Molecular and Cellular Biology

Volumn 15, Issue 11, 1995, Pages 6169-6177

  Clark, Melody E ^a   Mellon, Pamela L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; GONADORELIN; HOMEODOMAIN PROTEIN; NUCLEAR PROTEIN; THYMINE; TRANSCRIPTION FACTOR; VIRUS T ANTIGEN;

ANIMAL CELL; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; ENHANCER REGION; MOUSE; MUTATION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; SIMIAN VIRUS 40; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS; SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0028877438     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.15.11.6169     Document Type: Article

References (68)

1. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. 1987. Current protocols in molecular biology. John Wiley & Sons, New York.
2. Bendall, A. J., R. A. Sturm, P. A. Danoy, and P. L. Molloy. 1993. Broad binding-site specificity and affinity properties of octamer 1 and brain octamer-binding proteins. Eur. J. Biochem. 217:799-811.
3. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
4. Dailey, L., H. Yuan, and C. Basilico. 1994. Interaction between a novel F9-specific factor and octamer-binding proteins is required for cell-type-restricted activity of the fibroblast growth factor 4 enhancer. Mol. Cell. Biol. 14:7758-7769.
5. Das, G., and W. Herr. 1993. Enhanced activation of the human histone H2B promoter by an Oct-1 variant generated by alternative splicing. J. Biol. Chem. 268:25026-25032.
6. de Wet, J. R., K. V. Wood, M. DeLuca, D. R. Helinski, and S. Subramani. 1987. Firefly luciferase gene: structure and expression in mammalian cells. Mol. Cell. Biol. 7:725-737.
7. Findell, P. R., K. H. Wong, J. K. Jackman, and D. V. Daniels. 1993. Beta 1-adrenergic and dopamine (D1)-receptors coupled to adenylyl cyclase activation in GT1 gonadotropin-releasing hormone neurosecretory cells. Endocrinology 132:682-688.
8. Gonzalez-Manchon, C., L. M. Bilezikjian, A. Z. Corrigan, P. L. Mellon, and W. Vale. 1991. Activin-A modulates GnRH secretion from a GnRH-secreting neuronal cell line. Neuroendocrinology 54:373-377.
9. Gorman, C. 1985. High efficiency gene transfer into mammalian cells, p. 143-190. In D. M. Glover (ed.). DNA cloning: a practical approach. IRL Press, Oxford.
10. Gstaiger, M., L. Knoepfel, O. Georgiev, W. Schaffner, and C. M. Hovens. 1995. A B-cell coactivator of octamer-binding transcription factors. Nature (London) 373:360-362.
11. Hales, T. G., H. Kim, B. Longoni, R. W. Olsen, and A. J. Tobin. 1992. Immortalized hypothalamic GT1-7 neurons express functional γ-aminobutyric acid type A receptors. Mol. Pharmacol. 42:197-202.
12. Hara, Y., A. Rovescalli, Y. Kim, and M. Nirenberg. 1992. Structure and evolution of four POU domain genes expressed in mouse brain. Proc. Natl. Acad. Sci. USA 89:3280-3284.
13. He, X., and M. G. Rosenfeld. 1991. Mechanisms of complex transcriptional regulation: implications for brain development. Neuron 7:183-196.
14. He, X., M. N. Treacy, D. M. Simmons, H. A. Ingraham, L. W. Swanson, and M. G. Rosenfeld. 1989. Expression of a large family of POU-domain regulatory genes in mammalian brain development. Nature (London) 340:35-42.
15. Herr, W. 1992. Oct-1 and Oct-2: differential transcriptional regulation by proteins that bind to the same DNA sequence, p. 1103-1135. In S. L. McKnight and K. Yamamoto (ed.), Transcriptional regulation. Cold Spring Harbor Laboratory Press. Cold Spring Harbor, N.Y.
16. Inouye, S., and M. Inouye. 1987. Oligonucleotide-directed site-specific mutagenesis using double-stranded plasmid DNA, p. 181-206. In S A Narang (ed.), Synthesis and applications of DNA and RNA. Academic Press, New York.
17. Jaffe, J., M. Hochberg, J. Riss, T. Hasin, L. Reich, and R. Laskov. 1995. Cloning, sequencing and expression of two isoforms of the murine oct-1 transcription factor. Biochim. Biophys. Acta 1261:201-209.
18. Johnson, D. G., L. Carayannopoulos, J, D. Capra, P. W. Tucker, and J. H. Hanke. 1990. The ubiquitous octamer-binding protein(s) is sufficient for transcription of immunoglobulin genes. Mol. Cell. Biol. 10:982-990.
19. Johnson, P., and S. McKnight. 1989. Eukaryotic transcriptional regulatory proteins. Annu. Rev. Biochem. 58:799-839.
20. Katsuki, M., M. Sato, M. Kimura, M. Yokoyama, K. Kobayashi, and T. Nomura. 1988. Conversion of normal behavior to shiverer by myelin basic protein antisense cDNA in transgenic mice. Science 241:593-595.
21. Kohler, P. O., and W. E. Bridson. 1971. Isolation of hormone-producing clonal lines of human choriocarcinoma. J. Clin. Endocrinol. 32:683-687.
22. Kutoh, E., P. Stromstedt, and L. Poellinger. 1992. Functional interference between the ubiquitous and constitutive octamer transcription factor 1 (OTF-1) and the glucocorticoid receptor by direct protein-protein interaction involving the homeo subdomain of OTF-1. Mol. Cell. Biol. 12:4960-4969.
23. Lee, K. A. W., A. Bindereif, and M. R. Green. 1988. A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA aplicing. Gene Anal. Tech. 5:22-31.
24. Liposits, Z., I. Merchenthaler, W. C. Wetsel, J. J. Reid, P. L. Mellon, R. I. Weiner, and A. Negro-Vilar. 1991. Morphological characterization of immortalized hypothalamic neurons synthesizing luteinizing hormone-releasing hormone. Endocrinology 129:1575-1583.
25. Martinez de la Escalera, G., A. L. H. Choi, and R. I. Weiner. 1992. Generation and synchronization of gonadotropin-releasing hormone (GnRH) pulses: intrinsic properties of the GT1-1 GnRH neuronal cell line. Proc. Natl. Acad. Sci. USA 89:1852-1855.
26. Martinez de la Escalera, G., F. Gallo, A. L, H. Choi, and R. I. Weiner. 1992. Dopaminergic regulation of the GT1 gonadotropin-releasing hormone (GnRH) neuronal cell lines: stimulation of GnRH release via D1-receptors positively coupled to adenylate cyclase. Endocrinology 131:2965-2971.
27. Mathis, J. M., D. M. Simmons, X. He, L. W. Swanson, and M. G. Rosenfeld. 1992. Brain 4: a novel mammalian POU domain transcription factor exhibiting restricted brain-specific expression. EMBO J. 11:2551-2561.
28. Maue, R. A., S. D. Kraner, R. H. Goodman, and G. Mandel. 1990. Neuron-specific expression of the rat brain type II sodium channel gene is directed by upstream regulatory elements. Neuron 4:223-231.
29. McDermott, J. C., M. C. Cardoso, Y.-T. Yu, V. Andres, D. Leifer, D. Krainc, S. A. Lipton, and B. Nadal-Ginard. 1993. hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors. Mol. Cell. Biol. 13:2564-2577.
30. McKay, R. D. G. 1989. The origins of cellular diversity in the mammalian central nervous system. Cell 38:815-821.
31. Mellon, P. L., S. A. Eraly, D. D. Belsham, M. A. Lawson, M. E. Clark, D. B. Whyte, and J. J. Windle. 1995. An immortal cell culture model of hypothalamic gonadotropin-releasing hormone neurons. Methods 7:303-310.
32. 1 globin gene using a new SV40 host-vector system. Cell 27:279-288.
33. Mellon, P. L., J. J. Windle, P. Goldsmith, C. Pedula, J. Roberts, and R. I. Weiner. 1990. Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis. Neuron 5:1-10.
34. Mitchell, P. J., and R. Tjian. 1989. Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 245:371-378.
35. Monuki, E. S., R. Kuhn, G. Weinmaster, B. D. Trapp, and G. Lemke. 1990. Expression and activity of the POU transcription factor SCIP. Science 249: 1300-1303.
36. Moretto, M., F. J. Lopez, and A. Negro-Vilar. 1993. Nitric oxide regulates luteinizing hormone-releasing hormone secretion. Endocrinology 133:2399-2402.
37. Oberdick, J., R. J. Smeyne, J. R. Mann, S. Zackson, and J. I. Morgan. 1990. A promoter that drives transgene expression in cerebellar Purkinje and retinal bipolar neurons. Science 248:223-226.
38. O'Connor, M., and H.-U. Bernard. 1995. Oct-1 activates the epithelial-specific enhancer of human papillomavirus type 16 via a synergistic interaction with NF1 at a conserved composite regulatory element. Virology 207: 77-88.
39. Robertson, L. M., T. K. Kerppola, M. Vendrell, D. Luk, R. J. Smeyne, C. Bocchiaro, J. I. Morgan, and T. Curran. 1995. Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements. Neuron 14:241-252.
40. Rosenfeld, M. G. 1991. POU-domain transcription factors: pou-er-ful developmental regulators. Genes Dev. 5:897-907.
41. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
42. Schäler, H. R. 1991. Octamania: the POU factors in murine development. Trends Genet. 7:323-329.
43. Schöler, H. R., A. K. Hatzopoulos, R. Balling, N. Suzuki, and P. Gruss. 1989. A family of octamer-specific proteins present during mouse embryogenesis: evidence for germlinc-specific expression of an Oct factor. EMBO J. 8:2543-2550.
44. Schreiber, E., R. E. Merchant, O. D. Wiestler, and A. Fontana. 1994. Primary brain tumors differ in their expression of octamer deoxyribonucleic acid-binding transcription factors from long-term cultured glioma cell lines. Neurosurgery 34:129-135.
45. Schwanzel-Fukuda, M., K. L. Jorgenson, H. T. Bergen, G. D. Weesner, and D. W. Pfaff. 1992. Biology of normal luteinizing hormone-releasing hormone neurons during and after their migration from olfactory placode. Endocr. Rev. 13:623-634.
46. Schwanzel-Fukuda, M., and D. W. Pfaff. 1989. Origin of luteinizing hormone-releasing hormone neurons. Nature (London) 338:161-164.
47. Seed, B., and J. Y. Sheen. 1988. A simple phase-extraction assay for chloramphenicol acyltransferase activity. Gene 67:271-277.
48. Staudt, L., and M. J. Lenardo. 1991. Immunoglobin gene transcription. Annu. Rev. Immunol. 9:373-398.
49. Staudt, L. M., H. Singh, R. Sen, T. Wirth, P. A. Sharp, and D. Baltimore. 1986. A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes. Nature (London) 323:640-643.
50. Stoykova, A. S., S. Sterrer, J. R. Erselius, A. K. Hatzopoulos, and P. Gruss. 1992. Mini-Oct and Oct-2c: two novel, functionally diverse murine Oct-2 gene products are differentially expressed in the CNS. Neuron 8:541-558.
51. Strubin, M., J. W. Newell, and P. Matthias. 1995. OBF-1. a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. Cell 80:497-506.
52. Sturm, R., T. Baumruker, B. R. Franza, and W. Herr. 1987. A 100-kD HcLa cell octamer binding protein (OBF100) interacts differently with two separate octamer-related sequences within the SV40 enhancer. Genes Dev. 1:1147-1160.
53. Suri, C., B. P. Fung, A. S. Tischler, and D. M. Chikaraishi. 1993. Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice. J. Neurosci. 13:1280-1291.
54. Sutcliffe, J. G. 1988. mRNA in the mammalian central nervous system. Annu. Rev. Neurosci. 11:157-198.
55. Suzuki, N., W. Peter, T. Ciesiolka, P. Gruss, and H. R. Schöler. 1993. Mouse Oct-1 contains a composite homeodomain of human Oct-1 and Oct-2. Nucleic Acids Res. 21:245-252.
56. Tamura, T.-A., A. Aoyama, T. Inque, M. Miura, H. Okano, and K. Mikoshiba. 1989. Tissue-specific in vitro transcription from the mouse myelin basic protein promoter. Mol. Cell. Biol. 9:3122-3126.
57. Todaro, G. J., and H. Green. 1963. Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J. Cell Biol. 17:299-313.
58. Tumilowicz, J. J., W. W. Nichols, J. J. Cholon, and A. E. Greene. 1970. Definition of a continuous human cell line derived from neuroblastoma. Cancer Res. 30:2110-2118.
59. Turner, E. E., K. J. Jenne, and M. G. Rosenfeld. 1994. Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid. Neuron 12:205-218.
60. Tverberg, L. A., and A. F. Russo. 1993. Regulation of the calcitonin/calcitonin gene-related peptide gene by cell-specific synergy between helix-loophelix and octamer-binding transcription factors. J. Biol. Chem. 268:15965-15973.
61. Verrijzer, C. P., A. J. Kal, and P. C. Van der Vliet. 1990. The DNA binding domain (POU domain) of transcription factor oct-1 suffices for stimulation of DNA replication. EMBO J. 9:1883-1888.
62. Voss, J. W., L. Wilson, and M. G. Rosenfeld. 1991. POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter. Genes Dev. 5:1309-1320.
63. Walker, S., S. Hayes, and P. O'Hare. 1994. Site-specific conformational alteration of the Oct-1 POU domain-DNA complex as the basis for differential recognition by Vmw65 (VP16). Cell 79:841-852.
64. Wetsel, W. C., M. M. Valença, I. Merchenthaler, Z. Liposits, F. J. López, R. I, Weiner, P. L. Mellon, and A. Negro-Vilar. 1992. Intrinsic pulsatile secretory activity of immortalized LHRH secreting neurons. Proc. Natl. Acad. Sci. USA 89:4149-4153.
65. Whyte, D. B., M. A. Lawson, D. D. Belsham, S. A. Eraly, C. T. Bond, J. P. Adelman, and P. L. Mellon. 1995. A neuron-specific enhancer targets expression of the gonadotropin-rcleasing hormone gene to hypothalamic neurosecretory neurons. Mol. Endocrinol. 9:467-477.
66. Windle, J. J., R. I. Weiner, and P. L. Mellon. 1990. Cell Lines of the pituitary gonadotrope lineage derived by targeted oncogenesis in transgenic mice. Mol. Endocrinol. 4:597-603.
67. Wuenschell, C. W., N. Mori, and D. J. Anderson. 1990. Analysis of SCG10 gene expression in transgenic mice reveals that neural specificity is achieved through selective derepression. Neuron 4:595-602.
68. Yu, Y.-T., R. E. Breilbart, L. B. Smoot, Y. Lee, V. Mahdavi, and B. Nadal-Ginard. 1992. Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factors. Genes Dev. 6:1783-1798.