Sodium pivalate reduces cardiac carnitine content and increases glucose oxidation without affecting cardiac functional capacity

Life Sciences

Volumn 57, Issue 24, 1995, Pages 2237-2244

  Morris, G S ^a   Zhou, Q ^a   Wolf, B A ^d   Christos, S C ^d   DiDomenico, D F ^d   Shug, A L ^b,c   Paulson, D J ^d  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b MIDWESTERN UNIVERSITY   (United States)

^c Metab Analysis Laboratories Inc   (United States)

^d NONE

Author keywords

cardiac metabolism; cardiac myosin; carnitine; glucose oxidation; sodium pivalate; working heart model

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; BICARBONATE; CARNITINE; CITRATE SYNTHASE; HEXOKINASE; ISOENZYME; MYOSIN; PIVALIC ACID;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE OXIDATION; HEART FUNCTION; HEART MUSCLE CONTRACTILITY; HEART MUSCLE METABOLISM; HEART PERFUSION; ISOLATED HEART; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; TISSUE LEVEL;

3-HYDROXYACYL COA DEHYDROGENASES; ANIMAL; CARNITINE; CITRATE (SI)-SYNTHASE; GLUCOSE; HEART; HEXOKINASE; ISOENZYMES; MALE; MYOCARDIUM; MYOSINS; OXIDATION-REDUCTION; PENTANOIC ACIDS; RATS; RATS, SPRAGUE-DAWLEY; SUPPORT, NON-U.S. GOV'T;

ANIMALIA;

EID: 0028877067     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/0024-3205(95)02216-6     Document Type: Article

References (29)

1. Mechanisms for altered carnitine content in hypertrophied rat hearts.
2. Effects of a rat-free diet on growing female rats with special reference to the endocrine system.
3. Fatty acid oxidation and mechanical performance of volume-overloaded rat hearts.