Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate: Implications for gene-specific therapy

Circulation

Volumn 92, Issue 12, 1995, Pages 3381-3386

  Schwartz, P J ^a   Priori, S G ^a   Locati, E H ^a   Napolitano, C ^a   Cantu, F ^a   Towbin, J A ^a   Keating, M T ^a   Hammoude, H ^a   Brown, A M ^a   Chen, L S K ^a   Colatsky, T J ^a  

^a UNIVERSITY OF PAVIA   (Italy)

Author keywords

death, sudden; genes; long QT syndrome; mexiletine

Indexed keywords

MEXILETINE; SODIUM CHANNEL;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG RESPONSE; EXERCISE; FEMALE; GENE MUTATION; HEART ARREST; HEART RATE; HUMAN; LONG QT SYNDROME; MALE; PRIORITY JOURNAL; SYNCOPE;

EID: 0028874658     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.92.12.3381     Document Type: Article

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