Synthesis and Biological Evaluation of N6-Cycloalkyl Derivatives of 1-Deazaadenine Nucleosides: A New Class of Anti-Human Immunodeficiency Virus Agents

Journal of Medicinal Chemistry

Volumn 38, Issue 20, 1995, Pages 4019-4025

  Cristalli, Gloria ^a   Vittori, Sauro ^a   Eleuteri, Alessandra ^a   Volpini, Rosaria ^a   Camaioni, Emidio ^a   Lupidi, Giulio ^a   Mahmood, Naheed ^b   Bevilacqua, Francesca ^c   Palù, Giorgio ^c  

^a UNIVERSITY OF CAMERINO   (Italy)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

^c UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 DEAZAADENOSINE DERIVATIVE; 2 CHLORO 6 N CYCLOHEPTYL 2' DEOXY 1 DEAZAADENOSINE; ADENINE NUCLEOTIDE DERIVATIVE; ADENOSINE DEAMINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; DOSE RESPONSE; DRUG POTENCY; DRUG SYNTHESIS; ENZYME SUBSTRATE; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; VERO CELL;

ADENOSINE; ADENOSINE DEAMINASE; ANIMAL; ANTIVIRAL AGENTS; CERCOPITHECUS AETHIOPS; HERPESVIRUS 1, HUMAN; HIV-1; HUMAN; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; VERO CELLS;

EID: 0028874506     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00020a017     Document Type: Article

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