메뉴 건너뛰기




Volumn 15, Issue 1, 1995, Pages 4S-10S

The evolution of the serotonin-dopamine antagonist concept

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; DOPAMINE 2 RECEPTOR; HALOPERIDOL; NEUROLEPTIC AGENT; RISPERIDONE; SEROTONIN RECEPTOR;

EID: 0028870605     PISSN: 02710749     EISSN: 1533712X     Source Type: Journal    
DOI: 10.1097/00004714-199502001-00002     Document Type: Article
Times cited : (62)

References (65)
  • 1
    • 0025757280 scopus 로고
    • Role of serotonin in therapy of depression, related disorders
    • 1
    • 1. Fuller RW. Role of serotonin in therapy of depression, related disorders. J Clin Psychiatry 1991;52:52–7.
    • (1991) J Clin Psychiatry , vol.52 , pp. 52-57
    • Fuller, R.W.1
  • 3
    • 84960994447 scopus 로고
    • Antagonism between lsd and 5-hydroxytryptarnine
    • 3
    • 3. Gaddum JH. Antagonism between LSD and 5-hydroxytryptarnine. J Physiol 1953;121:15P.
    • (1953) J Physiol , vol.121 , pp. 15P
    • Gaddum, J.H.1
  • 4
    • 84951655689 scopus 로고
    • On the relationship of serotonin to schizophrenia
    • 4
    • 4. Woolley DW, Shaw E. On the relationship of serotonin to schizophrenia. BMJ 1954;2:122.
    • (1954) BMJ , vol.2 , pp. 122
    • Woolley, D.W.1    Shaw, E.2
  • 5
    • 0000924038 scopus 로고
    • Un nouveau stabiliseur vegetatif, le 4560 rp
    • 5
    • 5. Laborit H, Hugenard P, Alluarne R. Un nouveau stabiliseur vegetatif, le 4560 RP. Presse Méd 1952;60:206–8.
    • (1952) Presse Méd , vol.60 , pp. 206-208
    • Laborit, H.1    Hugenard, P.2    Alluarne, R.3
  • 6
    • 0011154120 scopus 로고
    • Trente-huit cas de psychoses traitée par la cure prolongée et continue due 4560 rp
    • 6, Le Congrés des Al. et Neurol. de Langue Fr, Paris: Masson et Cie
    • 6. Delay J, Deniker P. Trente-huit cas de psychoses traitée par la cure prolongée et continue due 4560 RP. Le Congrés des Al. et Neurol. de Langue Fr. In: Compte rendu du Congrés. Paris: Masson et Cie, 1952.
    • (1952) Compte Rendu Du Congrés
    • Delay, J.1    Deniker, P.2
  • 7
    • 78651116398 scopus 로고
    • Effect of chlorpromazine or haloperidol on formation of 3-methoxytyramine and normetanephrine in mouse brain
    • 7
    • 7. Carlsson A, Lindqvist M. Effect of chlorpromazine or haloperidol on formation of 3-methoxytyramine and normetanephrine in mouse brain. Acta Pharmacol Toxicol 1963;20:140–4.
    • (1963) Acta Pharmacol Toxicol , vol.20 , pp. 140-144
    • Carlsson, A.1    Lindqvist, M.2
  • 8
    • 0013893886 scopus 로고
    • The significance of dopamine receptor blockade for the mechanism of action of neuroleptic drugs
    • 8
    • 8. van Rossum JM. The significance of dopamine receptor blockade for the mechanism of action of neuroleptic drugs. Arch Int Pharmacodyn Ther 1966;160:492–4.
    • (1966) Arch Int Pharmacodyn Ther , vol.160 , pp. 492-494
    • Van Rossum, J.M.1
  • 9
    • 0017068246 scopus 로고
    • Antipsychotic drug doses and neuroleptic/dopamine receptors
    • 9
    • 9. Seeman P, Lee T, Chau-Wong M, Wong K. Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature 1976; 261:717–9.
    • (1976) Nature , vol.261 , pp. 717-719
    • Seeman, P.1    Lee, T.2    Chau-Wong, M.3    Wong, K.4
  • 10
    • 0017255979 scopus 로고
    • Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
    • 10
    • 10. Creese I, Burt DR, Snyder SH. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science 1976;192:481–3.
    • (1976) Science , vol.192 , pp. 481-483
    • Creese, I.1    Burt, D.R.2    Snyder, S.H.3
  • 12
    • 0342515984 scopus 로고
    • Blood platelet 5-ht levels in psychiatric patients
    • 12
    • 12. Todrick A, Tait AC, Marshall EF. Blood platelet 5-HT levels in psychiatric patients. J Ment Sci 1960;106:884–90.
    • (1960) J Ment Sci , vol.106 , pp. 884-890
    • Todrick, A.1    Tait, A.C.2    Marshall, E.F.3
  • 13
    • 0014882268 scopus 로고
    • Livelli ematici di serotonina piatrinica in schizofrenici
    • 13
    • 13. Torre M, Vergani E, Gaira S. Livelli ematici di serotonina piatrinica in schizofrenici. Acta Neurol 1970;25:740–6.
    • (1970) Acta Neurol , vol.25 , pp. 740-746
    • Torre, M.1    Vergani, E.2    Gaira, S.3
  • 14
    • 0016670454 scopus 로고
    • Elevated blood serotonin concentrations in unmedicated chronic schizophrenic patients: A preliminary study
    • 14
    • 14. Garelis E, Gillin JC, Wyatt RI, Neff N. Elevated blood serotonin concentrations in unmedicated chronic schizophrenic patients: a preliminary study. Am J Psychiatry 1975;132:184–6.
    • (1975) Am J Psychiatry , vol.132 , pp. 184-186
    • Garelis, E.1    Gillin, J.C.2    Wyatt, R.I.3    Neff, N.4
  • 15
    • 70449257639 scopus 로고
    • Recherches sur le comportement de la serotonine dans le serum sanguine des schizophrenes
    • 15
    • 15. Jus A, Laskowska D, Zimny S. Recherches sur le comportement de la serotonine dans le serum sanguine des schizophrenes. Ann Med Psychol 1958;116:898–913.
    • (1958) Ann Med Psychol , vol.116 , pp. 898-913
    • Jus, A.1    Laskowska, D.2    Zimny, S.3
  • 16
    • 70449309978 scopus 로고
    • Blood and urinary serotonin and 5-hydroxyindole acetic acid levels in schizophrenic patients and normal subjects
    • 16
    • 16. Feldstein A, Hoagland H, Freeman H. Blood and urinary serotonin and 5-hydroxyindole acetic acid levels in schizophrenic patients and normal subjects. J Nerv Ment Dis 1959;129:62–8.
    • (1959) J Nerv Ment Dis , vol.129 , pp. 62-68
    • Feldstein, A.1    Hoagland, H.2    Freeman, H.3
  • 17
    • 0342958699 scopus 로고
    • A relationship between blood serotonin concentration and behaviour in psychiatric patients
    • 17
    • 17. Halevy A, Moos RH, Solomon EF. A relationship between blood serotonin concentration and behaviour in psychiatric patients. J Psychiatr Res 1965;3:1–10.
    • (1965) J Psychiatr Res , vol.3 , pp. 1-10
    • Halevy, A.1    Moos, R.H.2    Solomon, E.F.3
  • 18
    • 0019510058 scopus 로고
    • Increased whole blood serotonin concentrations in chronic schizophrenic patients
    • 18
    • 18. DeLisi LE, Neckers LM, Weinberger DR, Wyatt RJ. Increased whole blood serotonin concentrations in chronic schizophrenic patients. Arch Gen Psychiatry 1981;38:647–50.
    • (1981) Arch Gen Psychiatry , vol.38 , pp. 647-650
    • Delisi, L.E.1    Neckers, L.M.2    Weinberger, D.R.3    Wyatt, R.J.4
  • 19
    • 0020696725 scopus 로고
    • 5-hydroxyindoleacetic acid in schizophrenic patients with enlarged cerebral ventricles
    • 19
    • 19. Potkin SG, Weinberger DR, Linnoila M, Wyatt RJ. Low CSF 5-hydroxyindoleacetic acid in schizophrenic patients with enlarged cerebral ventricles. Am J Psychiatry 1983;140:21–5.
    • (1983) Am J Psychiatry , vol.140 , pp. 21-25
    • Potkin, S.G.1    Weinberger, D.R.2    Linnoila, M.3    Wyatt, R.J.4    Low, C.S.F.5
  • 20
    • 0021110216 scopus 로고
    • Csf 5-hiaa and suicide in non-depressed schizophrenics
    • 20
    • 20. vanPraag HM. CSF 5-HIAA and suicide in non-depressed schizophrenics. Lancet 1983;2:977–8.
    • (1983) Lancet , vol.2 , pp. 977-978
    • Vanpraag, H.M.1
  • 23
    • 0026800944 scopus 로고
    • 5-hydroxyindoleacetic acid in cerebrospinal fluid and prediction of suicidal liehaviour in schizophrenia
    • 23
    • 23. Cooper SJ, Kelly CB, King DJ. 5-hydroxyindoleacetic acid in cerebrospinal fluid and prediction of suicidal liehaviour in schizophrenia. Lancet 1992;340:940–1.
    • (1992) Lancet , vol.340 , pp. 940-941
    • Cooper, S.J.1    Kelly, C.B.2    King, D.J.3
  • 24
    • 84939313085 scopus 로고
    • Neurophysiological properties of psychotomimetics
    • 24, eds, Vol, Part, Berlin: Springer-Verlag
    • 24. Aghajanian GK. Neurophysiological properties of psychotomimetics. In: Hoffineister R, Stille G, eds. Handbook of experimental pharmacology. Vol. 55. Part 2. Berlin: Springer-Verlag 1981:89–110.
    • (1981) Handbook of Experimental Pharmacology , vol.55 , Issue.2 , pp. 89-110
    • Aghajanian, G.K.1    Hoffineister, R.2    Stille, G.3
  • 25
    • 0000358118 scopus 로고
    • A biochemical and pharmacological suggestion about certain mental disorders
    • 25
    • 25. Woolley DW, Shaw E. A biochemical and pharmacological suggestion about certain mental disorders. Proc Natl Acad Sci USA 1984;40:228–31.
    • (1984) Proc Natl Acad Sci USA , vol.40 , pp. 228-231
    • Woolley, D.W.1    Shaw, E.2
  • 27
    • 0022655642 scopus 로고
    • Intravenous lisuride corrects oscillations in motor performance in parkinson’s disease
    • 27
    • 27. Obeso JA, Luquin MR, Martinez-Lage JM. Intravenous lisuride corrects oscillations in motor performance in Parkinson’s disease. Ann Neurol 1986;19:31–5.
    • (1986) Ann Neurol , vol.19 , pp. 31-35
    • Obeso, J.A.1    Luquin, M.R.2    Martinez-Lage, J.M.3
  • 28
    • 0017658058 scopus 로고
    • Agranulocytosis in patients treated with clozapine
    • 28, A study of the Finnish epidemic
    • 28. Amsler HA, Teehovi L, Barth E, Harjula K, Vinopio P. Agranulocytosis in patients treated with clozapine. A study of the Finnish epidemic. Acta Psychiatr Scand 1977;56:241–8.
    • (1977) Acta Psychiatr Scand , vol.56 , pp. 241-248
    • Amsler, H.A.1    Teehovi, L.2    Barth, E.3    Harjula, K.4    Vinopio, P.5
  • 29
    • 0023812652 scopus 로고
    • The clozaril collaborative study group. Clozapine for the treatment of resistant schizophrenia: A double blind comparison with chlorpromazine
    • 29
    • 29. Kane JM, Honigfeld G, Singer J, Meltzer HY, the Clozaril Collaborative Study Group. Clozapine for the treatment of resistant schizophrenia: a double blind comparison with chlorpromazine. Arch Gèn Psychiatry 1988;45:789–96.
    • (1988) Arch Gèn Psychiatry , vol.45 , pp. 789-796
    • Kane, J.M.1    Honigfeld, G.2    Singer, J.3    Meltzer, H.Y.4
  • 30
    • 0024468426 scopus 로고
    • Development of the clozaril patient monitoring system
    • 30
    • 30. Bastani B, Alphs LD, Meltzer HY. Development of the Clozaril Patient Monitoring System. Psychopharmacology 1989;99:S122–5.
    • (1989) Psychopharmacology , vol.99 , pp. S122
    • Bastani, B.1    Alphs, L.D.2    Meltzer, H.Y.3
  • 31
    • 0028237637 scopus 로고
    • Risperidone: A novel antispychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacological proflle
    • 31, suppl
    • 31. Leysen JE, Janssen PMF, Megens AAHP, Schotte A. Risperidone: a novel antispychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacological proflle. J Clin Psychiatry 1994;55(suppl 5):5–12.
    • (1994) J Clin Psychiatry , vol.55 , Issue.5 , pp. 5-12
    • Leysen, J.E.1    Janssen, P.M.F.2    Megens, A.A.H.P.3    Schotte, A.4
  • 32
    • 0016774530 scopus 로고
    • The serotonergic system in the brain and its possible functional connections with other aminergic systems
    • 32
    • 32. Samanin R, Garattini S. The serotonergic system in the brain and its possible functional connections with other aminergic systems. Life Sci 1979;17:1201–10.
    • (1979) Life Sci , vol.17 , pp. 1201-1210
    • Samanin, R.1    Garattini, S.2
  • 33
    • 0017196483 scopus 로고
    • Serotoninergic modulation of dopamine response from the nucleus accumbens
    • 33
    • 33. Costall B, Naylor RJ, Marsden CB, Pycock CJ. Serotoninergic modulation of dopamine response from the nucleus accumbens. J Pharm Pharmacol 1976;28:523–6.
    • (1976) J Pharm Pharmacol , vol.28 , pp. 523-526
    • Costall, B.1    Naylor, R.J.2    Marsden, C.B.3    Pycock, C.J.4
  • 34
    • 0019364554 scopus 로고
    • Iqjections of doparninergic, cholinergic, serotoninergic and gabaergic drugs into the nucleus accumbens: Effects on locomotor activity in the rat
    • 34
    • 34. Jones DL, Morgenson GJ, Wu M. Iqjections of doparninergic, cholinergic, serotoninergic and GABAergic drugs into the nucleus accumbens: effects on locomotor activity in the rat. Neuropharmacology 1981;20:29–37.
    • (1981) Neuropharmacology , vol.20 , pp. 29-37
    • Jones, D.L.1    Morgenson, G.J.2    Wu, M.3
  • 35
    • 0020375803 scopus 로고
    • Basal ganglia disease
    • 35
    • 35. Marsden CD. Basal ganglia disease. Lancet 1982;2:1141–6.
    • (1982) Lancet , vol.2 , pp. 1141-1146
    • Marsden, C.D.1
  • 36
    • 0021249563 scopus 로고
    • Asymmetric dopamine and serotonin in nigrostriatal and limbic structures of the trained circling rat
    • 36
    • 36. Yamamoto BK, Freed CR. Asymmetric dopamine and serotonin in nigrostriatal and limbic structures of the trained circling rat. Brain Res 1984;297:115–9.
    • (1984) Brain Res , vol.297 , pp. 115-119
    • Yamamoto, B.K.1    Freed, C.R.2
  • 37
    • 0021257650 scopus 로고
    • The inhibitory gabaergic influence on striatal serotonergic neurons depends on the habenulo-raphe pathways
    • 37
    • 37. Nishikawa T, Scatton B. The inhibitory GABAergic influence on striatal serotonergic neurons depends on the habenulo-raphe pathways. Brain Res 1984;304:157–61.
    • (1984) Brain Res , vol.304 , pp. 157-161
    • Nishikawa, T.1    Scatton, B.2
  • 38
    • 0026091799 scopus 로고
    • The mechanism of action of novel antipsychotic drugs
    • 38
    • 38. Meltzer HY. The mechanism of action of novel antipsychotic drugs. Schizophr Bull 1991;17:263–87.
    • (1991) Schizophr Bull , vol.17 , pp. 263-287
    • Meltzer, H.Y.1
  • 41
    • 0027268149 scopus 로고
    • Serotonin function and treatment responses to clozapine in schizophrenic patients
    • 41
    • 41. Kahn RS, Davidson M, Siever L, Gabriel S, Apter S, Davis KL. Serotonin function and treatment responses to clozapine in schizophrenic patients. Am J Psychiatry 1993;150:1337–42.
    • (1993) Am J Psychiatry , vol.150 , pp. 1337-1342
    • Kahn, R.S.1    Davidson, M.2    Siever, L.3    Gabriel, S.4    Apter, S.5    Davis, K.L.6
  • 44
    • 0023147574 scopus 로고
    • Effect of ritanserin, a selective serotonin-s2 antagonist, on parkinsonian rest tremor
    • 44
    • 2 antagonist, on parkinsonian rest tremor. Curr Ther Res 1987;41:298–300.
    • (1987) Curr Ther Res , vol.41 , pp. 298-300
    • Hildebrand, J.1    Delecluse, F.2
  • 46
    • 0001074568 scopus 로고
    • Serotonin-s2 receptor blockers in the treatment of chronic schizophrenia
    • 46, suppl
    • 46. Gelders Y, Vanden Bussche G, Reyntjens A, Janssen P. Serotonin-S2 receptor blockers in the treatment of chronic schizophrenia. Clin Neuropharmacol 1986;9(suppl 4):325–7.
    • (1986) Clin Neuropharmacol , vol.9 , Issue.4 , pp. 325-327
    • Gelders, Y.1    Vanden Bussche, G.2    Reyntjens, A.3    Janssen, P.4
  • 49
    • 0028358082 scopus 로고
    • An open clinical and biochemical study of ritanserin in acute patients with schizophrenia
    • 49
    • 49. Wiesel F-A, Nordstrûm A-L, Farde L, Eriksson B. An open clinical and biochemical study of ritanserin in acute patients with schizophrenia. Psychopharmacology 1994;114:31–8.
    • (1994) Psychopharmacology , vol.114 , pp. 31-38
    • Wiesel, F.-A.1    Nordstrûm, A.-L.2    Farde, L.3    Eriksson, B.4
  • 55
    • 0028342655 scopus 로고
    • Risperidone in the treatment of schizophrenia
    • 55
    • 55. Marder SR, Meibach RC. Risperidone in the treatment of schizophrenia. Am J Psychiatry 1994;151:825–35.
    • (1994) Am J Psychiatry , vol.151 , pp. 825-835
    • Marder, S.R.1    Meibach, R.C.2
  • 56
    • 0026444131 scopus 로고
    • The international risperidone research group. Risperidone in the treatment of chronic schizophrenic patients
    • 56, an international double-blind parallel-group study versus haloperidol, suppl
    • 56. Müller-Spahn F, the International Risperidone Research Group. Risperidone in the treatment of chronic schizophrenic patients. an international double-blind parallel-group study versus haloperidol. Clin Neuropharmacol 1992;15(suppl 1):90A–1A.
    • (1992) Clin Neuropharmacol , vol.15 , Issue.1 , pp. 90A-91A
  • 57
    • 0028206243 scopus 로고
    • Extrapyramidal side effects and tolerability of risneridone: A review
    • 57, suppl
    • 57. Owens DGC. Extrapyramidal side effects and tolerability of risneridone: a review. J Clin Psychiatr.y 1994;55(suppl 5):29–35.
    • (1994) J Clin Psychiatr.Y , vol.55 , Issue.5 , pp. 29-35
    • Owens, D.G.C.1
  • 59
    • 0019945902 scopus 로고
    • Negative symptoms in schizophrenia: Definition and reliability
    • 59
    • 59. Andreasen NC. Negative symptoms in schizophrenia: definition and reliability. Arch Gen Psychiatry 1982;39:784–8.
    • (1982) Arch Gen Psychiatry , vol.39 , pp. 784-788
    • Andreasen, N.C.1
  • 60
    • 33846011025 scopus 로고
    • The brief psychiatric rating scale
    • 60
    • 60. Overall JE, Gorham DR. The brief psychiatric rating scale. Psychol Rep 1962;10:799–812.
    • (1962) Psychol Rep , vol.10 , pp. 799-812
    • Overall, J.E.1    Gorham, D.R.2
  • 62
    • 0026718710 scopus 로고
    • Positron emission tomographic analysis of central dl and d2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine: Relation to extrapyramidal side effects
    • 62
    • l and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine: relation to extrapyramidal side effects. Arch Gen Psychiatry 1992;49:589–99.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 589-599
    • Farde, L.1    Nordstrom, D.L.2    Wiesel, F.3    Pauli, S.4    Halldin, G.5    Sedvall, G.6
  • 63
    • 0026643193 scopus 로고
    • Clozapine, single photon emission tomography and the d2 dopamine receptor blockade hypothesis of schizophrenia
    • 63
    • 63. Pilowsky LS, Costa DC, Ell PJ, Murray RM, Verhoeff NPLG, Kerwin RW. Clozapine, single photon emission tomography and the D2 dopamine receptor blockade hypothesis of schizophrenia. Lancet 1992;340:199–202.
    • (1992) Lancet , vol.340 , pp. 199-202
    • Pilowsky, L.S.1    Costa, D.C.2    Ell, P.J.3    Murray, R.M.4    Verhoeff, N.P.L.G.5    Kerwin, R.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.