A suboptimal src 3' splice site is necessary for efficient replication of Rous sarcoma virus

Virology

Volumn 206, Issue 2, 1995, Pages 1099-1107

  Zhang, Lei ^a   Stoltzfus, C Martin ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0028870109     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1995.1033     Document Type: Article

References (33)

1. Amendl, B. A., Hesslein, D., Chang, L.-J., and Stoltzfus, C. M. (1994). Presence of negative and positive c/s-acting RNA splicing elements within and flanking the first tat coding exon of the human immunodeficiency virus type 1. Mot. Celt. Biot. 14, 3960-3970.
2. Arrigo, S., and Beemon, K. (1988). Regulation of Rous sarcoma virus RNA splicing and stability. Mol. Cell. Biol. 8, 4858-4867.
3. Baivay, L., Pret, A., Libri, D., Helfman, D. M., and Fiszman, M. Y. (1994). Splicing of the alternative exons of the chicken, rat, and Xenopus fi tropomysin transcripts requires class-specific elements. J. Biol. Chem. 269, 19675-19678.
4. Berberich, S. L., Macias, M., Zhang, L., Turek, L. P., and Stoltzfus, C. M. (1990), Comparison of Rous sarcoma virus RNA processing in chicken and mouse fibroblasts.-Evidence for double-spliced RNA in nonpermissive mouse cells. J. Virol. 64, 4313-4320.
5. Berberich, S. L, and Stoltzfus, C. M. (1991a). Analysis of spliced and unspliced Rous sarcoma virus RNAs early and late after infection of chicken embryo fibroblasts: Effect of cell culture conditions. Virology 182, 135-144.
6. Berberich, S. L., and Stoltzfus, C. M. (1991b). Mutations in the regions of the Rous sarcoma virus 3' splice sites: Implications for regulation of alternative splicing. J. Virol 65, 2640-2646.
7. Cullen, B. R., (1991). Regulation of human immunodeficiency virus replication. Anna. Rev. Microbiol. 45, 219-250.
8. Fu, X.-D., Katz, R. A., Skaika, A. M., and Maniatis, T. (1991). The role of branchpoint and 3'-exon sequences in the control of balanced splicing of avian retrovirus RNA. Genes Dev. 5, 211-220.
9. Goodwin, R. G., Rottman, F. M., Callaghan, T., Kung, H.-J., Maroney, P. A., and Nilsen, T. W. (1986). c-erbB activation in avian leukosis virus-induced erythroblastosis: Multiple epidermal growth factor receptor mRNAs are generated by alternative RNA processing. Moi. Cell. Biol. 6, 3128-3133.
10. Green, M. R. (1991). Biochemical mechanisms of constitutive and regulated pre-mRNA splicing. Annu. Rev. Cell Biol. 7, 559-599.
11. Horowitz, D. S., and Krainer, A. R. (1994), Mechanisms for selecting 5' splice sites in mammalian pre-mRNA splicing. Trends Genet. 10, 100-106.
12. Katz, R. A., Kotler, M., and Skaika, A. M. (1988). C/s-Acting intron mutations that affect the efficiency of avian retroviral RNA splicing: Implication for mechanisms of control. J. Virol. 62, 2686-2695.
13. Katz, R. A., and Skaika, A. M. (1990). Control of retroviral splicing through maintenance of suboptimal splicing signals. Mol. Cell. Biol. 10, 696-704.
14. Knight, J. B., Stinski, M. F., and Stoltzfus, C. M. (1993). Avian sarcoma virus RNA synthesis, RNA splicing and virus production in human fibroblasts: Effect of coinfection with human cytomegalovirus. J Gen. Virol. 74, 2629-2636.
15. Linial, M., and Blair, D. (1982). Genetics of retroviruses. In 'The Molecular Biology of Tumor Viruses" (R. Weiss, N. Teich, H. Varmus, and J. Coffin, Eds.), pp, 649-784. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
16. McNally, M. T., and Beemon, K. (1992). Intronic sequences and 3' splice sites control Rous sarcoma virus RNA splicing. J. Virol. 66, 6-11.
17. Nilsen, T. W., Maroney, P. A., Goodwin, R. G., Rottman, F. M., Crittenden, L. B., Raines, M. A., and Kung, H.-J. (1985). C-erbB activation in ALV-induced erythroblastosis: Novel RNA processing and promoter insertion result in expression of an amino-truncated EGF-receptor. Cell 41, 719-726.
18. Omer, C. A., Pogue-Geile, K., Guntaka, R., Staskus, K. A., and Faras, A. J. (1983). Involvement of direct repeated sequences in the generation of deletions of the avian sarcoma virus src gene. J. Virol. 47, 380-382.
19. Pel ley, R. J., Moscovici, C., Hughes, S.P and Kung, H.-J. (1988). Proviral-activated c-erbB is leukemogenic but not sarcomagenic; Characterization of a replication-competent retrovirus containing the activated c-erbB. I Virol, 62, 1840-1844.
20. Raines, M. A., Maihle, N. J., Moscovici, C., Crittenden, L., and Kung, H.-J. (1988), Mechanism of c-erbB transduction Newly released transducing viruses retain poly (A) tracts of erbB transcripts and encode C-terminally intact erbB proteins. J. Virol. 62, 2437-2443.
21. Rodcigno, R. F., Weiner, M., and Garcia-Bianco, M. A. (1993). A mutational analysis of the polypyrimidine tracts of introns: Effects of sequence differences in pyrimidine tracts on splicing. J. Biot. Chem, 268, 11222-11229.
22. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989). "Molecular Cloning: A Laboratory Manual'’ 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
23. Sanger, F., Niklen, S., and Coulson, A. R. (1977). DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad Sci. USA 74, 5463-5467.
24. Sarkar, G., and Somer, S. S. (1990). The "megaprimer" method of site-directed mutagenesis. BioTechniques 8, 404-407.
25. Staffa, A., and Cochrane, A, (1994). The tat/rev intron of human immunodeficiency virus type 1 is inefficiently spliced because of suboptimal signals in the 3' splice site. J. Virol. 68, 3071-3079.
26. Stoltzfus, C. M. (1988). Synthesis and processing of avian sarcoma retrovirus RNA. Adv. Virus Res. 35, 1-37.
27. Stoltzfus, C. M., and Dane, R. W. (1983). Particles of reduced infectivity and deficient in envelope glycoproteins are produced in cycloleu-cine-treated B77 avian sarcoma virus-infected chicken embryo fibroblasts. J. Virol. 45, 1207-1210.
28. Stoltzfus, C. M., and Fogarty, S. J. (1989). Multiple regions in the Rous sarcoma virus src gene intron act in cis to affect accumulation of unspliced RNA. J. Virol. 63, 1669-1676.
29. Strohman, R., Moss, P., Micou-Eastwood, J., Spector, D., Przybyla, A., and Peterson, B, (1977). Messenger RNA for myosin polypeptides: Isolation from single myogenic cell cultures. Cell 10, 265-273.
30. Varmus, H., and Swanstrom, R. (1982). Replication of retroviruses. In "RNA Tumor Viruses" (R. Weiss, N, Teich, H. Varmus, and J. Coffin, Eds.), pp, 369-512. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
31. Voynow, S. L, and Coffin, J. M. (1985). Evolutionary variants of Rous sarcoma virus: Large deletion mutants do not result from homologous recombination. J. Viroi. 55, 67-78.
32. Wigler, M., Pellicer, A., Silverstein, S., and Axel, R. (1978). Biochemical transfer of single-copy eukaryotic genes using total cellular DNA as donor. Cell 14, 725-734.
33. Yamamoto, T., Tyagi, J. S., Fagon, J. B., Jay, G., deCrombrugghe, B., and Pastan, I. (1980). Molecular mechanism for the capture and excision of the transformating gene of avian sarcoma virus as suggested by analysis of recombinant clones. J. Virol. 35, 436-443.