Recombinant adenovirus vector expressing wildtype p53 is a potent inhibitor of prostate cancer cell proliferation

Urology

Volumn 46, Issue 6, 1995, Pages 843-848

  Srivastava, Shiv ^a,b,c   Katayose, Dai ^a,b,c   Tong, Yue Ao ^a,b,c   Craig, Caroline R ^a,b,c   McLeod, David G ^a,b,c   Moul, Judd W ^a,b,c   Cowan, Kenneth H ^a,b,c   Seth, Prem ^a,b,c  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b WALTER REED ARMY MEDICAL CENTER   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; PROTEIN P53; VIRUS VECTOR;

ADENOVIRUS; ARTICLE; CANCER CELL; CANCER INHIBITION; CONTROLLED STUDY; CYTOSTASIS; CYTOTOXICITY; GENE INDUCTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; TUMOR SUPPRESSOR GENE; VIRUS RECOMBINANT;

ADENOVIRUSES, HUMAN; BLOTTING, WESTERN; CELL DIVISION; DNA DAMAGE; DNA, NEOPLASM; GENETIC VECTORS; HUMAN; MALE; PRECIPITIN TESTS; PROSTATIC NEOPLASMS; PROTEIN P53; RECOMBINATION, GENETIC; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED;

EID: 0028869090     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/S0090-4295(99)80355-0     Document Type: Article

References (32)

1. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis
2. p53 and the Li-Fraumeni syndrome
3. Molecular biology of prostate cancer.
4. Molecular biology of prostate cancer: oncogenes and tumor suppressor genes
5. p53 is mutated in a subset of advanced-stage human prostate cancers
6. p53 protein accumulation and gene mutation in the progression of human prostate carcinoma
7. Immunohistochemical determination of p53 protein nuclear accumulation in prostatic adenocarcinoma
8. Hormone resistant prostatic adenocarcinoma. An evaluation of prognostic factors in pre- and post-treatment specimens
9. Alteration of the tumor suppressor gene p53 in a high fraction of hormone refractory prostate cancer
10. Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles
11. p53 function and dysfunction
12. Cell cycle control and cancer
13. Gene therapy: adenovirus vectors
14. Pathway of adenovirus entry into cells
15. Gene transfer to freshly isolated human respiratory epithelial cells in vitro using a replication deficient adenovirus containing the human cystic fibrosis transmembrane conductance regulator cDNA
16. Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of wild-type p53 gene
17. In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma
18. Cytotoxic effects of adenovirus mediated wild type p53 protein expression in normal and tumor mammary epithelial cells
19. Spontaneous metastasis of cells of the human prostate carcinoma cell line PC-3 in athymic nude mice
20. Establishment and characterization of a new human prostatic carcinoma cell line (DuPro-1)
21. Inhibition of retinoblastoma protein phosphorylation by the combined effect of interferon-γ and tumor necrosis factor-∝
22. Detection of both mutant and wild-type p53 protein in normal skin fibroblasts and demonstration of a shared “second-hit” on p53 in diverse tumors from a cancer-prone family with Li-Fraumeni syndrome
23. Electrophoretic transfer of proteins from polyacrylamide gels into nitrocellulose sheets: procedure and some applications
24. Suppression of human colorectal carcinoma cell growth by wild-type p53
25. p53: the ultimate tumor suppressor gene?
26. WAF1, a potential mediator of p53 tumor suppression
27. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis
28. Demonstration of a rational strategy for human prostate cancer gene therapy
29. Immunotherapy of prostate cancer in Dunning rat model: use of cytokine gene modified tumor vaccine
30. Growth suppression mediated by transfection of p53 in Hut292DM human lung cancer cells expressing endogenous wild type p53 protein
31. Gene therapy for treatment of androgen independent and PSA producing human prostate cancer
32. Adenovirusmediated p53 gene transfer in experimental prostate cancer