Synthesis and Characterization of a Highly Potent and Effective Antagonist of Retinoic Acid Receptors

Journal of Medicinal Chemistry

Volumn 38, Issue 24, 1995, Pages 4764-4767

  Johnson, Alan T ^a   Klein, Elliott S ^a   Gillett, Samuel J ^a   Wang, Liming ^a   Song, Tae K ^a   Pino, Mary E ^a   Chandraratna, Roshantha A S ^a  

^a ALLERGAN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [2 [5,6 DIHYDRO 5,5 DIMETHYL 8 (4 METHYLPHENYL) 2 NAPHTHYL]ETHYNYL]BENZOIC ACID; ALITRETINOIN; MIFEPRISTONE; RECEPTOR BLOCKING AGENT; RECEPTOR SUBTYPE; RETINOIC ACID; RETINOIC ACID DERIVATIVE; RETINOIC ACID RECEPTOR; RETINOIC ACID RECEPTOR ANTAGONIST; TAMOXIFEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CELL STRAIN HL 60; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; RECEPTOR BLOCKING; REPORTER GENE; TRANSACTIVATION;

ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; NAPHTHALENES; RECEPTORS, RETINOIC ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0028868608     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00024a003     Document Type: Article

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