Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-Å resolution: Implications for catalytic proton transfer and inhibitor design

Proceedings of the National Academy of Sciences of the United States of America

Volumn 92, Issue 24, 1995, Pages 10949-10953

  Boriack Sjodin, P A ^a   Heck, R W ^a   Laipis, P J ^a   Silverman, D N ^a   Christianson, D W ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

carbon dioxide hydration; enzymology; protein crystallography; zinc enzyme

Indexed keywords

ACETAZOLAMIDE; CARBON DIOXIDE; CARBONATE DEHYDRATASE; GLUCOSE; MITOCHONDRIAL ENZYME;

ARTICLE; CRYSTALLOGRAPHY; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYMOLOGY; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTON TRANSPORT;

ACETAZOLAMIDE; AMINO ACID SEQUENCE; ANIMAL; BINDING SITES; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; FOURIER ANALYSIS; HUMAN; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MITOCHONDRIA, LIVER; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; PROTONS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, U.S. GOV'T, P.H.S.; ZINC;

MURINAE;

EID: 0028867081     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.92.24.10949     Document Type: Article

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