Inhibition of CYP1A2 and CYP3A4 by Oltipraz Results in Reduction of Aflatoxin Bt Metabolism in Human Hepatocytes in Primary Culture

Cancer Research

Volumn 55, Issue 23, 1995, Pages 5574-5579

  Langouët, Sophie ^a   Coles, Brian ^b,e   Morel, Fabrice ^a   Becquemont, Laurent ^c   Beaune, Philippe ^c   Guengerich, F Peter ^d   Ketterer, Brian ^b   Guillouzo, André ^a  

^a RENNES UNIVERSITY HOSPITAL   (France)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d VANDERBILT UNIVERSITY   (United States)

^e National Center for Toxicological Research   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLCHOLANTHRENE; AFLATOXIN B1; GLUTATHIONE TRANSFERASE; OLTIPRAZ; RIFAMPICIN;

ARTICLE; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME ANALYSIS; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL; TOXIN ANALYSIS;

AFLATOXIN B1; AGED; ANTICARCINOGENIC AGENTS; CELLS, CULTURED; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; GLUTATHIONE TRANSFERASE; HUMAN; INFANT; LIVER; MALE; METHYLCHOLANTHRENE; MIDDLE AGE; MIXED FUNCTION OXYGENASES; OXIDOREDUCTASES; PYRAZINES; RIFAMPIN; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0028865229     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

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