Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease

Journal of Neuroscience

Volumn 15, Issue 11, 1995, Pages 7727-7733

  Sagot, Y ^a   Dubois Dauphin, M ^a   Tan, S A ^b   De Bilbao, F ^a   Aebischer, P ^b   Martinou, J C ^c   Kato, A C ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c GLAXO INST FOR MOLECULAR BIOLOGY   (Switzerland)

Author keywords

animal model of motor neuron disease; axonal degeneration; Bcl 2; pmn pmn mice; progressive motor neuronopathy; treatment of neurodegenerative disease

Indexed keywords

ONCOPROTEIN;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL LOSS; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; FACIAL NERVE; GENE EXPRESSION; MOTONEURON; MOTOR NEUROPATHY; MOUSE; NERVE DEGENERATION; NONHUMAN; PERIKARYON; PHRENIC NERVE; PRIORITY JOURNAL; PROTO ONCOGENE; TRANSGENIC MOUSE;

EID: 0028865136     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.15-11-07727.1995     Document Type: Article

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