Characterization of the taxol binding site on the microtubule: 2-(m-azidobenzoyl)taxol photolabels a peptide (amino acids 217-231) of β-tubulin

Journal of Biological Chemistry

Volumn 270, Issue 35, 1995, Pages 20235-20238

  Rao, Srinivasa ^a   Orr, George A ^a   Chaudhary, Ashok G ^b   Kingston, David G I ^b   Horwitz, Susan Band ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3 AZIDOBENZOYL)TAXOL; 3' (4 AZIDOBENZAMIDO)TAXOL; BETA TUBULIN; CYANOGEN BROMIDE; MICROTUBULE PROTEIN; PACLITAXEL; PACLITAXEL DERIVATIVE; TERPENOID; TRYPSIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG STRUCTURE; MICROTUBULE; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN CROSS LINKING; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET IRRADIATION;

AFFINITY LABELS; AMINO ACID SEQUENCE; ANIMAL; AZIDES; BINDING SITES; BRAIN; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYANOGEN BROMIDE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MICROTUBULE PROTEINS; MOLECULAR SEQUENCE DATA; PACLITAXEL; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; SUPPORT, U.S. GOV'T, P.H.S.; TRITIUM; TRYPSIN; TUBULIN;

EID: 0028861177     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.270.35.20235     Document Type: Article

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