Protein kinase C involvement in maintenance and modulation of noradrenaline release in the mouse brain cortex

British Journal of Pharmacology

Volumn 116, Issue 6, 1995, Pages 2757-2763

  Schroeder, G E ^a   Kotsonis, P ^a   Musgrave, I F ^a   Majewski, H ^a  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

mouse cortex; noradrenaline release; phorbol ester; polymyxin B; prejunctional modulation; Protein kinase C

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; IDAZOXAN; NORADRENALIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL DIBUTYRATE; POLYMYXIN B; POTASSIUM CHANNEL; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; TETRYLAMMONIUM;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; MALE; MOUSE; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RECEPTOR BLOCKING;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMAL; CEREBRAL CORTEX; COMPARATIVE STUDY; DIOXANES; DOWN-REGULATION; ELECTRIC STIMULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; IDAZOXAN; IMIDAZOLES; MALE; MICE; NOREPINEPHRINE; PHORBOL 12,13-DIBUTYRATE; POLYMYXIN B; POTASSIUM CHANNELS; PROTEIN KINASE C; SUPPORT, NON-U.S. GOV'T; TETRAETHYLAMMONIUM; TETRAETHYLAMMONIUM COMPOUNDS; TIME FACTORS; TRITIUM;

EID: 0028860857     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1995.tb17238.x     Document Type: Article

References (38)

1. Differences in phorbolester‐induced down regulation of protein kinase C between cell Unes
2. Polymyxin B, a selective inhibitor of protein kinase C, diminishes the release of noradrenaUne and the enhancement of release caused by phorbol 12,13‐dibutyrate
3. 2‐autoreceptor modulated release of noradrenaUne
4. A detailed study on the effect of protein kinase C activation on alpha2‐adrenoceptor coupled modulation of norephinephrine release
5. Enhancement of noradrenaUne release by 12‐O‐tetra‐decanoyl phorbol‐13‐acetate, an activator of protein kinase C
6. Anomalous rectification in squid giant axon injected with tetraethy 1 ammonium chloride
7. Assessment of guanine nucleotide effects on catecholamine secretion from permeabilized adrenal chromaffin cells
8. Influence of phorbol esters on stimulation‐induced noradrenaline release and contractile force of isolated guinea‐pig atria
9. Protein kinase C and alpha2‐adrenoceptor‐mediated inhibition of noradrenaline release from the rat tail artery
10. Second messengers involved in the mechanism of action of bradykinin in sensory neurons in culture
11. Staurosporine counteracts the phorbolester induced enhancement of neurotransmitter release in hippocampus
12. Phosphorylation of B‐50 (GAP‐43) is correlated with neurotransmitter release in rat hippocampal sUces
13. Long term treatment with phorbol esters suggests a permissive role for protein kinase C in the enhancement of noradrenaUne release
14. Role of calcium channels and protein kinase C for release of norepinephrine and neuropeptide Y
15. Phorbol ester‐mediated enhancement of hippocampal noradrenaline release: which ion channels are involved?
16. 3H]‐noradrenaline
17. Phosphorylation of annexin II tetramer by protein kinase C inhibits aggregation of Upid vesicles by the protein
18. 2+ ‐dependent protein kinase
19. Down regulation of protein kinase C in neuronal cells: effects on neurotransmitter release
20. 2+‐dependent protein kinase
21. Effect of phorbol esters and polymyxin B on modulation of noradrenaUne release in mouse atria
22. Phorbol ester enhancement of neurotransmitter release from rat brain synaptosomes
23. Intracellular signalling by hydrolysis of phosphoUpids and activation of protein kinase C
24. Synaptosomal protein kinase C subspecies: B. Down‐regulation promoted by phorbol ester and its effect on evoked norepinephrine release
25. Staurosporine, K‐252 and UCN‐01: potent but non‐specific inhibitors of protein kinases
26. Inhibition of protein kinase C (PKC) and three other protein kinases by several reference PKC inhibitors
27. Modulation of ion channel activity: a key function of the protein kinase C enzyme family
28. Activation of protein kinase C potentiates norepinephrine release from sinus node
29. Inhibition by cycUc AMP of phorbol ester‐potentiated noradrenaUne release from guinea‐pig synaptosomes
30. Factorial experiments
31. Protein kinase C
32. Modulation of neurotransmitter release by presynaptic autoreceptors
33. Presynaptic sites of isolated canine saphenous veins are more sensitive to protein kinase C than postsynaptic ones
34. Phorbol 12,13‐dibutyrate enhances electrically stimulated neuromessenger release from rat dorsal hippocampal sUces in vitro
35. 3H] dopamine from amygdala slices in vitro: effects of 4β‐phorbol 12,13‐dibutyrate, 4α‐phorbol 12,13‐dideconate and polymyxin B
36. Phorbol ester, an activator of protein kinase C enhances calcium‐dependent release of sympathetic neurotransmitter
37. Depolarizing stimuli and neurotransmitters utilize separate pathways to activate protein kinase C
38. Regulation of the chromaffin granule aggregation activity of annexin I by phosphorylation