Enantiodivergent Synthesis of the Key Intermediate for Aphanorphine by Chemoenzymatic Process

Tetrahedron

Volumn 51, Issue 45, 1995, Pages 12211-12216

  O Hallinan, Keith ^a   Honda, Toshio ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; APHANORPHINE;

ARTICLE; DRUG SYNTHESIS; ENANTIOMER; ENZYME ACTIVITY; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0028858096     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4020(95)00784-6     Document Type: Article

References (12)

1. Enantiocontrolled synthesis of (+)-aphanorphine from (R)-O-benzylglycidol: assignment of absolute configuration
2. The enantioselective total synthesis of natural (?)-aphanorphine
3. Synthesis of (�)-aphanorphine via an aminylium ion intermediate
4. Chemistry of Sodium Borohydride and Diborane. IV. Reduction of Carboxylic Acids to Alcohols with Sodium Borohydride through Mixed Carbonic-Carboxylic Acid Anhydrides