Mechanism of soluble epoxide hydrolase: Formation of an α-hydroxy ester-enzyme intermediate through Asp-333

Journal of Biological Chemistry

Volumn 270, Issue 45, 1995, Pages 26923-26930

  Borhan, Babak ^a   Jones, A Daniel ^a   Pinot, Franck ^a   Grant, David F ^a   Kurth, Mark J ^a   Hammock, Bruce D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CHALCONE; EPOXIDE HYDROLASE; OXYGEN 18; STEARIC ACID DERIVATIVE;

ARTICLE; CATALYSIS; ENZYME MECHANISM; ENZYME SUBSTRATE; HYDROLYSIS; MASS SPECTROMETRY; MOLECULAR WEIGHT; PRIORITY JOURNAL;

ANIMAL; ASPARTIC ACID; BINDING SITES; CATALYSIS; EPOXIDE HYDROLASES; EPOXY COMPOUNDS; IN VITRO; MICE; MODELS, CHEMICAL; RECOMBINANT PROTEINS; SOLUBILITY; STEARIC ACIDS; STEREOISOMERISM; SUBSTRATE SPECIFICITY; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028856676     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.270.45.26923     Document Type: Article

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