Adjuvant activity of non-toxic Quillaja saponaria Molina components for use in ISCOM matrix

Vaccine

Volumn 13, Issue 14, 1995, Pages 1375-1382

  Rönnberg, Bengt ^a   Fekadu, Makonnen ^a   Morein, Bror ^a  

^a NONE

Author keywords

components; ISCOM; Quillaja saponaria Molina

Indexed keywords

IMMUNOLOGICAL ADJUVANT; IMMUNOMODULATING AGENT; SAPONIN;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN PRESENTATION; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; INFLUENZA VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; TOXICITY;

ADJUVANTS, IMMUNOLOGIC; ANIMAL; CHICK EMBRYO; COMPARATIVE STUDY; FEMALE; HEMOLYSIS; INTRACELLULAR FLUID; ISCOMS; MICE; MICE, INBRED ICR; OXIDOREDUCTASES; PLANT EXTRACTS; PROTEINS; RNA; SAPONINS; SUPPORT, NON-U.S. GOV'T; TREES;

EID: 0028856624     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0264-410X(95)00105-A     Document Type: Article

References (18)

1. Iscoms and immunostimulation with viral antigens
2. The requirement of lipids for the formation of immunostimulating complexes (iscoms)
3. Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex
4. On the structure of immune-stimulating saponin-lipid complexes (iscoms)
5. Advances in adjuvant technology and application
6. Thin layer chromatographic fingerprinting of commercially available saponins
7. Saponin adjuvants. III. Isolation of a substance from Quillaja saponaria Molina with adjuvant activity in foot- and-mouth disease vaccines
8. The iscom—an approach to subunit vaccines
9. A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes
10. Antigenic presentation of small molecules and synthetic peptides conjugated to a preformed iscom as carrier
11. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of proteindye binding
12. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
13. + cytotoxic T cells by immunization with purified HIV-1 envelope protein in iscoms
14. Effect of iscoms and their adjuvant moiety (matrix) on the initial proliferation and IL-2 responses: comparison of spleen cells from mice inoculated with iscoms and/or matrix
15. Involvement of interleukin-2 and interferongamma in the immune response induced by influenza virus iscoms
16. Systemic cytokine profiles in BALB/C mice immunized with trivalent influenza vaccine containing MF59 oil emulsion and other advanced adjuvants
17. Saponin and other haemolysins (vitamin A, aliphatic amines, polyene antibiotics) as adjuvants for SRBC in the mouse. Evidence for a role for cholesterol-binding in saponin adjuvanticity
18. Effect of the aqueous extract and saponin fraction from the flowers of Verbascum thapsiforme on protein biosynthesis in a rat liver ribosomal system