Interaction between external Na+ and mexiletine on Na+ channel in guinea-pig ventricular myocytes

Pflügers Archiv European Journal of Physiology

Volumn 431, Issue 1, 1995, Pages 101-109

  Ono, Masahiro ^a   Sunami, Akihiko ^a   Hiraoka, Masayasu ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Ion conducting pathways; Local anaesthetics; Mexiletine; Open channel block; Patch clamp technique; Single channel recording; Use dependent block of the Na+ current; Ventricular myocyte

Indexed keywords

LOCAL ANESTHETIC AGENT; MEXILETINE; SODIUM CHANNEL;

ANIMAL CELL; ARTICLE; BINDING SITE; GUINEA PIG; HEART VENTRICLE WALL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; SODIUM CONDUCTANCE; SODIUM CURRENT;

ALGORITHMS; ANIMAL; ANTI-ARRHYTHMIA AGENTS; GUINEA PIGS; HEART; HEART VENTRICLE; IN VITRO; MEXILETINE; MYOCARDIUM; PATCH-CLAMP TECHNIQUES; SODIUM; SODIUM CHANNELS; SUPPORT, NON-U.S. GOV'T;

EID: 0028856328     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/BF00374382     Document Type: Article

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