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Volumn 697, Issue 1-2, 1995, Pages 35-43

Immunoreactivity for Bcl-2 protein within neurons in the Alzheimer's disease brain increases with disease severity

Author keywords

Alzheimer's disease; Apoptosis; AT8; Bcl 2; Cell death; Human brain; Immunohistochemistry; Neurofibrillary tangle; Oncogene; PHF 1

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENTORHINAL CORTEX; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NEUROFIBRILLARY TANGLE; ONCOGENE BCL2; PAIRED HELICAL FILAMENT; PRIORITY JOURNAL;

EID: 0028853727     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(95)00748-F     Document Type: Article
Times cited : (112)

References (35)
  • 1
    • 0027243086 scopus 로고
    • The proto-oncogenebcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
    • (1993) Cell , vol.73 , pp. 295-307
    • Allsopp1    Wyatt2    Paterson3    Davies4
  • 5
    • 0028362458 scopus 로고
    • A sequence of cytoskeletal changes related to the formation of neurofibrillary tangles and neuropil threads
    • (1994) Acta Neuropathol. , vol.87 , pp. 554-567
    • Braak1    Braak2    Mandelkow3
  • 6
    • 0024501122 scopus 로고
    • Thebcl-2 candidate proto-occogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 701-710
    • Chen1    Nourse2    Cleary3
  • 9
    • 0026640706 scopus 로고
    • Isolation and characterization of the chickenbcl-2 gene: expression in a variety of tissues including lymphoid and neuronal organs in adult and embryo
    • (1992) Nucl. Acids Res. , vol.20 , pp. 4187-4192
    • Eguchi1    Ewert2    Tsujimoto3
  • 12
    • 0025292866 scopus 로고
    • A preparation of Alzheimer paired helical filaments that display distinct τ proteins by polyacrylamide gel electrophoresis
    • 8th Edn.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5827-5831
    • Greenberg1    Davies2
  • 13
    • 0026582702 scopus 로고
    • Caenorhabditis elegans geneced-9 protects cells from programmed cell death
    • (1992) Nature , vol.356 , pp. 494-499
    • Hengartner1    Ellis2    Horvitz3
  • 14
    • 0028288277 scopus 로고
    • C. elegans cell survival geneced-9 encodes a functional homolog of the mammalian proto-encogene bcl-2
    • (1994) Cell , vol.76 , pp. 665-676
    • Hengartner1    Horvitz2
  • 18
    • 0027362667 scopus 로고
    • Investigation of the subcellular distribution of thebcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum and outer mitochondrial membranes
    • (1993) Cancer Res. , vol.53 , pp. 4701-4714
    • Krajewski1    Tanaka2    Takayama3    Schibler4    Fenton5    Read6
  • 20
    • 0028178385 scopus 로고
    • Bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS
    • (1994) Development , vol.120 , pp. 301-311
    • Merry1    Veis2    Hickey3    Korsmeyer4
  • 21
    • 84921161482 scopus 로고    scopus 로고
    • Miller, R.J., Bindokas, V.P., Marcuccilli, C.J., Krajewski, S., Reed, J.C. and Miller, R.J., Regulation of neuronal bcl-2 protein expression and calcium homeostasis by TGF-β confers wide-ranging protection on rat hippocampal neurons,Proc. Natl. Acad. Sci. USA, in press.
  • 23
    • 0027449187 scopus 로고
    • Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the c. elegans cell death geneced-3
    • (1993) Cell , vol.75 , pp. 653-660
    • Miura1    Zhu2    Rotello3    Hartwieg4    Yuan5
  • 25
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltval1    Milliman2    Korsmeyer3
  • 27
    • 0029016635 scopus 로고
    • Early association of reactive astrocytes with senile plaques in Alzheimer's disease
    • (1995) Exp. Neurol. , vol.132 , pp. 172-179
    • Pike1    Cummings2    Cotman3
  • 28
    • 0028335948 scopus 로고
    • Anchorage dependence, integrins and apoptosis
    • (1994) Cell , vol.77 , pp. 477-478
    • Ruoslahti1    Reed2
  • 29
    • 0027939401 scopus 로고
    • Early phosphorylation of tau in Alzheimer's disease occurs at Ser-202 and is preferentially located within neurites
    • (1994) Neuroreport , vol.5 , pp. 2358-2362
    • Su1    Cummings2    Cotman3
  • 31
    • 0028353008 scopus 로고
    • Alzheimer's disease: stereology in search of specific markers
    • (1994) Neurobiol. Aging , vol.15 , pp. 373-375
    • Vogels1
  • 32
    • 0021827944 scopus 로고
    • Simultaneous demonstration of multiple antigens by indirect immunofluorescence or immunogold staining
    • (1985) Histochemistry , vol.83 , pp. 47-56
    • Wang1    Larson2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.