Expression of tissue inhibitors of metalloproteinases: negative regulators of human glioblastoma invasion in vivo

Clinical & Experimental Metastasis

Volumn 13, Issue 1, 1995, Pages 57-62

  Mohanam, Sanjeeva ^a   Wu Wang, Shang ^a   Rayford, Alan ^a   Yamamoto, Masaaki ^a   Sawaya, Raymond ^a   Nakajima, Motowo ^b   Liotta, Lance A ^c   Nicolson, Garth L ^a   Stetler Stevenson, William G ^c   Rao, Jasti S ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

glioblastoma multiforme; invasion; matrix; metalloproteinases; metastasis; tissue inhibitors of metalloproteinases

Indexed keywords

METALLOPROTEINASE; METALLOPROTEINASE INHIBITOR;

ARTICLE; CANCER INVASION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; METASTASIS POTENTIAL; NORTHERN BLOTTING;

BLOTTING, NORTHERN; BRAIN NEOPLASMS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; GLYCOPROTEINS; HUMAN; METALLOENDOPEPTIDASES; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; PROTEINS; RNA, NEOPLASM; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TISSUE INHIBITOR OF METALLOPROTEINASES; TISSUE INHIBITOR-OF METALLOPROTEINASE-2;

EID: 0028852956     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/BF00144019     Document Type: Article

References (34)

1. The matrix-degrading metalloproteinases
2. Matrix metalloproteinases and their inhibitors in connective tissue remodelling
3. Tissue inhibitor of metalloproteinase (TIMP-2): A new member of the metalloproteinase inhibitor family
4. Human 72-kDa type IV collagenase forms a complex with tissue inhibitor of metalloproteinase designated TIMP-2
5. Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinase prevents dimerization, complex formation with interstitial collagenase and activation of the proenzyme with stromelysin
6. Regulation of autoactivation of human 72-kDa progelatinase by tissue inhibitor of metalloproteinase-2
7. Differential regulation of the expression of proteinase/antiproteinases in fibroblasts
8. Developmental expression of tissue inhibitor of metalloproteinase (TIMP) RNA
9. Expression of genes encoding type IV collagen degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells
10. Distribution of extracellular matrix proteins in primary human brain tumors: an immunohistochemical analysis
11. Metalloproteinase capable of destroying cultured brain tissue isolated from rat glioma cells
12. Expression of matrilysin and stromelysin in human glioma cells
13. Elevated levels of M, 92 000 type IV collagenase in human brain tumors
14. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding
15. Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues
16. Modulation of in vitro invasion of human glioblastoma cells by urokinase type plasminogen activator receptor antibody
17. Transforming growth factor-β suppresses the invasiveness of human fibrosarcoma cells in vitro by increasing expression of tissue inhibitor of metalloprotease
18. Effect of phorbol ester and cytokines on matrix metalloproteinase and tissue inhibitor of metalloproteinase expression in tumor and normal cell lines
19. Patterns of expression of metalloproteinases and their inhibitors in human malignant lymphomas
20. Expression of metalloproteinases and metalloproteinase inhibitors by fetal astrocytes and glioma cells
21. Evaluation of basement membrane components and the 72-kDa type IV collagenase in serous tumors of the ovary
22. Immunohistochemical distribution of type IV collagenase in normal, benign and malignant breast tissues
23. Type IV collagenase (Mr 72000) expression in human prostate: benign and malignant tissue
24. Induction and stimulation of 92-kDa gelatinase/type IV collagenase production in osteosarcoma and fibrosarcoma cell lines by tumor necrosis factor alpha
25. Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor β-1 in human fibroblasts
26. Purification and characterization of two related but distinct metalloproteinase inhibitors secreted by bovine aortic endothelial cells
27. Transgenic mice with hepatic TIMP-1 alteration: a model to study the role of TIMP-1 in liver carcinogenesis
28. Expression of human recombinant 72-kDa gelatinase and tissue inhibitor of metalloproteinase-2 (TIMP-2): characterization of complex and free enzyme
29. Plasma membrane dependent activation of the 72 kDa type IV collagenase is prevented by complex formation with TIMP-2
30. Suppression of invasion by inducible expression of tissue inhibitor of metalloproteinase-1 (TIMP-1) in B16-F10 melanoma cells
31. Loss of the metastatic phenotype by a human epidermoid carcinoma cell line HEp-3 is accompanied by increased expression of tissue inhibitor of metalloproteinase 2
32. Inhibition of collagenolytic activity and metastasis of tumor cells by a recombinant human tissue inhibitor of metalloproteinase
33. Tissue inhibitor of metalloproteinase 1 is a negative regulator of the metastatic ability of a human gastric cancer cell line KKLS in the chick embryo
34. Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases