Peroxisome assembly factor–2, a putative ATPase cloned by functional complementation on a peroxisome–deficient mammalian cell mutant

Nature Genetics

Volumn 11, Issue 4, 1995, Pages 395-401

  Tsukamoto, Toshiro ^a   Miura, Satoshi ^b   Nakai, Toshiki ^b   Yokota, Sadaki ^c   Shimozawa, Nobuyuki ^d   Suzuki, Yasuyuki ^d   Orii, Tadao ^d   Fujiki, Yukio ^e   Sakai, Fumie ^a   Bogaki, Akemi ^a   Yasumo, Hiroaki ^a   Osumi, Takashi ^a  

^a UNIVERSITY OF HYOGO   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c UNIVERSITY OF YAMANASHI   (Japan)

^d GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE;

ANIMAL CELL; ARTICLE; BINDING SITE; BIOGENESIS; CELL MUTANT; CELL ORGANELLE; FIBROBLAST; GENE ISOLATION; GENETIC COMPLEMENTATION; MAMMAL CELL; MOLECULAR CLONING; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; PROTEIN ASSEMBLY;

ACYLTRANSFERASES; ADENOSINETRIPHOSPHATASE; AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; BINDING SITES; CATALASE; CHO CELLS; CLONING, MOLECULAR; CYTOSOL; DNA, COMPLEMENTARY; FIBROBLASTS; GENETIC COMPLEMENTATION TEST; HAMSTERS; HUMAN; LIVER; MICROBODIES; MOLECULAR SEQUENCE DATA; MUTATION; OXIDOREDUCTASES; PEROXISOMAL DISORDERS; RATS; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SUPPORT, NON-U.S. GOV'T;

EID: 0028845671     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng1295-395     Document Type: Article

References (48)

1. van den Bosch, H., Schutgens, R. B. H., Wanders, R. JA. & Tager, J. M, Biochemistry of peroxisomes. A Rev. Biochem. 61, 157-197 (1992).
2. Kunau, W.-H. et al. Two complementary approaches to study peroxisome biogenesis in Saccharomyces cerevisiae: forward and reversed genetics. Biochimie 75, 209-224 (1993).
3. Subramani, S. Protein import into peroxisomes and biogenesis of the organelle. A Rev. Cell Biol. 9, 445-478 (1993).
4. Schutgens, R. B. H., Heymans, H. S. A., Wanders, RJA, van den Bosch, H. & Tager, J. M. Peroxisomal disorders: a newiy recognized group of genetic diseases. Eur. J. Pediatr. 144, 430-440 (1986).
5. Shimozawa, N. et al. Standardization of complementation grouping of peroxisome-deficient disorders and the second Zellweger patient with peroxisomal assembly factor-1 (PAF-1) defect. Am. J. hum. Genet. 52, 843-844(1993).
6. Tsukamoto, T., Yokota, S. & Fujiki, Y. Isolation and characterization of Chinese hamster ovary cell mutants defective in assembly of peroxisomes. J. Cell Biol. 110, 651-660 (1990).
7. Shimozawa, N., Tsukamoto, T., Suzuki, Y., Orii, T. & Fujiki, Y. Animal cell mutants represent two complementation groups of peroxisome-defective Zellweger syndrome. J. din. Invesl 90, 1864-1870 (1992).
8. Tsukamoto, T., Miura, S. & Fujiki, Y. Restoration by a 35K membrane protein of peroxisome assembly in a peroxisome-deficient mammalian ceil mutant. Nature 350, 77-81 (1991).
9. Shimozawa, N. et al. A human gene responsible for Zellweger syndrome that affects peroxisome assembly. Science 255, 1132-1134 (1992).
10. Tsukamoto, T., Shimozawa, N. & Fujiki, Y. Peroxisome assembly factor 1: Nonsense mutation in a peroxisome-deficient Chinese hamster ovary cell mutant and deletion analysis. Molec. cell. Biol. 14, 5458-5465 (1994).
11. Confalonieri, F. & Duguet, M. A 200-amino acid ATPase module in search of a basic function. BioEssays 17, 639-650 (1995).
12. Koller, K. J. & Brownstein, M. J. Use of a CDNA clone to identify a supposed precursor protein containing valosin. Nature 325, 542-545 (1987).
13. Peters, J.-M., Walsh, M. J. & Franke, W. W. An abundant and ubiquitous homo-oligomeric ring-shaped ATPase particle related to the putative vesicle fusion proteins Sec18p and NSF. EMBO J. 9, 1757-1767 (1990).
14. Frðlich, K.-U. et al. Yeast ceil cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression. J. Cell Bid. 114, 443-453 (1991).
15. Wilson, D. W. et al. A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast. Nature 339, 355-359 (1989).
16. Nelbock, P., Dillon, P. J., Perkins, A. & Rosen, CA A cDNA for a protein that interacts with the human immunodeficiency vims Tat transactivator. Science 248, 1650-1653(1990).
17. Thorsness, PE., White, K. H. & Fox, T. D. Inactivation of YME1, a member of the ftsH-SEC18-PAS1-CDC48 family of putative ATPase-encodíng genes, causes Increased escape of DNA from mitochondria in Saccharomyces cerevisiae. Molec. cell. Bid. 13, 5418-5426 (1993).
18. Nakai, T., Yasuhara, T., Fujiki, Y. & Ohashi, A. Multiple genes, including a member of the AAA family, are essential for degradation of unassembled subunit 2 of cytochrome c oxidase in yeast mitochondria. Molec. cell. Biol. 15, 4441-4452 (1995).
19. Dubiel, W., Ferrell, K., Pratt, G. & Rechsteiner, M. Subunit 4 of the 26 S protease is a member of a novel eukaryotic ATPase family. J. bid. Chem. 267, 22699-22702(1992).
20. Tomoyasu, T. et al. The Escherichia coli FtsH protein is a prokaryotic member of a protein family of putative ATPases involved in membrane functions, cell cycle control, and gene expression. J. Bacterid. 175, 1344-1351 (1993).
21. Spong, A. P. & Subramani, S. Cloning and characterization of PAS5: a gene required for peroxisome biogenesis in the methylotrophic yeast Pîchia pastoris. J. Cell Biol. 123, 535-548 (1993).
22. Voom-Brouwer, T., van der Leij, I., Hemrika, W., Distel, B. & Tabak, H. F Sequence of the PAS8 gene, the product of which is essential for biogenesis of peroxisomes in Saccharomyces cerevisiae. Biochim. biophys. Acta 1216, 325-328(1993).
23. Nuttiey, W. M. et al. PAY4, a gene required for peroxisome assembly in the yeast Yanowia lipolytlca, encodes a novel member of a family of putative ATPases. J. bid. Chem. 269, 556-566 (1994).
24. Erdmann, R. et al. PAS1, a yeast gene required for peroxisome biogenesis, encodes a member of a novel family of putative ATPase. Cell 04, 499-510 (1991).
25. Heyman, J A., Monosov, E. & Subramani, S. Role of the PAS1 gene of Pichia pastoris in peroxisome biogenesis. J. Cell Bid. 127, 1259-1273 (1994).
26. Walker, J. E., Saraste, M., Runswick, M. J. & Gay, N. J. Dìstanlty related sequences in the α-and β-subunŕts of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO. J. 1, 945-981 (1982).
27. Chin, D. T, Goff, S A, Webster, T., Smith, T. & Goldberg, A. L Sequence of the Ion gene in Escherichia coli. J. bioi. Chem. 263, 11718-11728 (1988).
28. Ogawa, H., Konishi, K., Takata, Y, Nakashima, H. & Fujioka, M. Rat glycine methyttransferase. Complete amino acid sequence deduced from a cDNA clone and characterization of the genomic DNA. Eur. J. Biochem. 168, 141-151 (1987).
29. Miyazawa, S. et al. Complete nucleotide sequence of cDNA and predicted amino acid sequence of rat acyl-CoA oxidase. J. bioi. Chem. 262, 8131-8137 (1987).
30. Osumi, T. et al. Amino-terminal presequence of the precursor of peroxisomal 3-ketoacyl-CoA thiolase is a cleavable signal peptide for peroxisomal targeting. Biochem. biophys. Res. Commun. 181, 947-954 (1991).
31. Hijikata, M., Ishii, N., Kagamiyama, H., Osumi, T. & Hashimoto, T. Structural analysis of cDNA for rat peroxisomal 3-ketoacyl-CoA thiolase. J. bioi Chem. 262, 8151-8158(1987).
32. Zoeller, R A, Morand, O. H. & Raetz, C. R. H. A possible role for plasmalogens in protecting animal cells against photosensitized killing, J. bioi. Chem. 263, 11590-11596(1988).
33. Morand, O. H., Allen, L-A. H., Zoeller, R A & Raetz, C. R. H. A rapid selection for animal cell mutants with defective peroxisomes. Biochim. biophys. Acta 1034, 132-141(1990).
34. Saraste, M., Sibbald, PR. & Wittinghofer, A The P-loop-a common motif in ATP-and GTP-bindìng proteins. Trends. Biochem. Sci. 15, 430-434(1990).
35. Bordo, D. & Argos, R Suggestions for "safe" residue substitutions in site-directed mutagenesis. J. molec. Bid. 217, 721-729 (1991).
36. Gordon, C., McGurk, G., Dillon, P., Rosen, C. & Hastie, N. D. Defective mitosis due to a mutation in the gene for a fisson yeast 26S protease subunit. Nature 366, 355-357 (1993).
37. Ghislain, M., Udvardy, A & Mann, C. S. cerevisiae 26S protease mutants arrest celt division in G2/metaphase. Nature 366, 358-362 (1993).
38. Dodt, G. et al. Mutations in the PTS1 receptor gene, PXR1, define complementation group 2 of the peroxisome biogenesis disorders. Nature Genet. 9, 115-125 (1995).
39. Wendland, M. & Subramani, S. Presence of cytoplasmic factors functional in peroxisomal protein import implicates organelle-associated defects in several human peroxisomal disorders. J. din. Invest. 92, 2462-2468 (1993).
40. Krause, T., Kunau, W.-H, & Erdmann, R. Effect of site-directed mutagenesis of conserved lysine residues upon Pas1 protein function in peroxisome biogenesis. Yeast 10, 1613-1620(1994).
41. imanaka, T., Small, G. M. & lazarow, P. B. Translocation of acyí-CoA oxidase into peroxisomes requires ATP hydrolysis but not a membrane potential. J. Cell Bid. 105, 2915-2922 (1987).
42. Wendland, M. & Subramani, S. Cytosol-dependent peroxisomal protein import in a permeabilized cell system. J. Cell Bid. 120, 675-685 (1993).
43. Chen, C. & Okayama, H. High-efficiency transformation of mammalian cells by plasmid DNA Molec. cell. Biol. 7, 2745-2752 (1987).
44. Takebe, Y. et al. SRα promoter an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat. Molec. cell. Bid. 8, 466-472 (1988).
45. Okayama, H. & Berg, P. A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells. Molec. cell. Biol. 3, 280-289 (1983).
46. Miura, S. et al. Carboxyl-terminal consensus Ser-Lys-Leu-related tripeptide of peroxisomal proteins functions in vitro as a minimal peroxisome-targeting signal. J. bid. Chem. 267, 14405-14411 (1992).
47. Miyazawa, S. et al. Peroxisome targeting signal of rat liver acyl-Coenzyme A oxidase resides at the carboxy terminus. Molec. cell. Bid. 9, 83-91 (1989).
48. Shimozawa, N., Suzuki, Y., Orii, T., Yokota, S. & Hashimoto, T. Biochemical and morphologic aspects of peroxisomes in the human rectal mucosa: diagnosis of Zellweger syndrome simplified by rectal biopsy. Pediatr. Res. 24, 723-727(1988).