-
1
-
-
0028121279
-
A cell cycle regulator potentially involved in genesis of many tumor types
-
Kamb, A., Gruis, N. A., Weaver-Feldhaus, J., Liu, Q., Harshman, K., Tavtigian, S. V., Stockert, E., Day, R. S., Johnson, B. E., and Skolnick, M. H. A cell cycle regulator potentially involved in genesis of many tumor types. Science (Washington DC), 264:436–440, 1994.
-
(1994)
Science (Washington DC)
, vol.264
, pp. 436-440
-
-
Kamb, A.1
Gruis, N.A.2
Weaver-Feldhaus, J.3
Liu, Q.4
Harshman, K.5
Tavtigian, S.V.6
Stockert, E.7
Day, R.S.8
Johnson, B.E.9
Skolnick, M.H.10
-
2
-
-
0028275733
-
Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
-
Nobori, T., Miura, K., Wu, D. J., Lois, A., Takabayashi, K., and Carson, D. A. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature (Lond.), 368:753–756, 1994.
-
(1994)
Nature (Lond.)
, vol.368
, pp. 753-756
-
-
Nobori, T.1
Miura, K.2
Wu, D.J.3
Lois, A.4
Takabayashi, K.5
Carson, D.A.6
-
3
-
-
0028033422
-
Rates of pl6 (MTS1) mutations in primary tumors with 9p loss
-
Cairns, P., Mao, L., Merlo, A., Lee, D. J., Schwab, D., Eby, Y., Tokino, K., van der Riet, P., Blaugrund, J. E., and Sidransky, D. Rates of pl6 (MTS1) mutations in primary tumors with 9p loss. Science (Washington DC), 265:415–417, 1994.
-
(1994)
Science (Washington DC)
, vol.265
, pp. 415-417
-
-
Cairns, P.1
Mao, L.2
Merlo, A.3
Lee, D.J.4
Schwab, D.5
Eby, Y.6
Tokino, K.7
van der Riet, P.8
Blaugrund, J.E.9
Sidransky, D.10
-
4
-
-
0028033270
-
Mutations and altered expression of pl6INK4 in human cancer
-
Okamoto, A., Demetrick, D. J., Spillare, E. A., Hagiwara, K., Hussain, S. P., Bennett, W. P., Forrester, K., Gerwin, B., Serrano, M., Beach, D. H., and Harris, C. C. Mutations and altered expression of pl6INK4 in human cancer. Proc. Natl. Acad. Sci. USA, 91:11045–11049, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11045-11049
-
-
Okamoto, A.1
Demetrick, D.J.2
Spillare, E.A.3
Hagiwara, K.4
Hussain, S.P.5
Bennett, W.P.6
Forrester, K.7
Gerwin, B.8
Serrano, M.9
Beach, D.H.10
Harris, C.C.11
-
5
-
-
0027960580
-
pi6 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma
-
Cheng, J. Q., Jhanwar, S. C., Klein, W. M., Bell, D. W., Lee, W. C., Altomare, D. A., Nobori, T., Olopade, O. I., Buckler, A. J., and Testa, J. R. pi6 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma. Cancer Res., 54:5547–5551, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 5547-5551
-
-
Cheng, J.Q.1
Jhanwar, S.C.2
Klein, W.M.3
Bell, D.W.4
Lee, W.C.5
Altomare, D.A.6
Nobori, T.7
Olopade, O.I.8
Buckler, A.J.9
Testa, J.R.10
-
6
-
-
0027946010
-
Rarity of somatic and germline mutations of the cyclin-dependent kinase 4 inhibitor gene, CDK4I, in melanoma
-
Ohta, M., Nagai, H., Shimizu, M., Rasio, D., Berd, D., Mastrangelo, M., Singh, A. D., Shields, J. A., Shields, C. L., Croce, C. M., and Huebner, K. Rarity of somatic and germline mutations of the cyclin-dependent kinase 4 inhibitor gene, CDK4I, in melanoma. Cancer Res., 54:5269–5272, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 5269-5272
-
-
Ohta, M.1
Nagai, H.2
Shimizu, M.3
Rasio, D.4
Berd, D.5
Mastrangelo, M.6
Singh, A.D.7
Shields, J.A.8
Shields, C.L.9
Croce, C.M.10
Huebner, K.11
-
7
-
-
0028070985
-
pl6 gene in uncultured tumours
-
Spruck, C. H., Gonzalez-Zulueta, M., Shibata, A., Simoneau, A. R., Lin, M. F., Gonzales, F., Tsai, Y. C., and Jones, P. A. pl6 gene in uncultured tumours. Nature (Lond.), 370:183–184, 1994.
-
(1994)
Nature (Lond.)
, vol.370
, pp. 183-184
-
-
Spruck, C.H.1
Gonzalez-Zulueta, M.2
Shibata, A.3
Simoneau, A.R.4
Lin, M.F.5
Gonzales, F.6
Tsai, Y.C.7
Jones, P.A.8
-
8
-
-
0028113410
-
Mutational analysis of CDKN2 (MTSl/pl6ink4) in human breast carcinomas
-
Xu, L., Sgroi, D., Sterner, C. J., Beauchamp, R. L., Pinney, D. M., Keel, S., Ueki, K., Rutter, J. L., Buckler, A. J., Louis, D. N., Louis, D. D., Gusella, J. F., and Ramesh, V. Mutational analysis of CDKN2 (MTSl/pl6ink4) in human breast carcinomas. Cancer Res., 54:5262–5264, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 5262-5264
-
-
Xu, L.1
Sgroi, D.2
Sterner, C.J.3
Beauchamp, R.L.4
Pinney, D.M.5
Keel, S.6
Ueki, K.7
Rutter, J.L.8
Buckler, A.J.9
Louis, D.N.10
Louis, D.D.11
Gusella, J.F.12
Ramesh, V.13
-
9
-
-
0027535235
-
Effects of DNA methylation on DNA-binding proteins and gene expression
-
Tate, P. H., and Bird, A. P. Effects of DNA methylation on DNA-binding proteins and gene expression. Curr. Opin. Genet. Dev., 3:226–231, 1993.
-
(1993)
Curr. Opin. Genet. Dev.
, vol.3
, pp. 226-231
-
-
Tate, P.H.1
Bird, A.P.2
-
10
-
-
0028072991
-
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
-
Herman, J. G., Latif, F., Weng, Y., Lerman, M. I., Zbar, B., Liu, S., Samid, D., Duan, D. S., Gnarra, J. R., Linehan, W. M., and Baylin, S. B. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc. Natl. Acad. Sci. USA, 91:9700–9704, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9700-9704
-
-
Herman, J.G.1
Latif, F.2
Weng, Y.3
Lerman, M.I.4
Zbar, B.5
Liu, S.6
Samid, D.7
Duan, D.S.8
Gnarra, J.R.9
Linehan, W.M.10
Baylin, S.B.11
-
11
-
-
0029011539
-
5’ CpG island methylation is associated with transcriptional silencing of the tumor suppressor pl6/CDKN2/MTSl in human cancers
-
Merlo, A., Herman, J. G., Mao, L., Lee, D. J., Gabrielson, E., Burger, P. C., Baylin, S. B., and Sidransky, D. 5’ CpG island methylation is associated with transcriptional silencing of the tumor suppressor pl6/CDKN2/MTSl in human cancers. Nat. Med., 1:686–692, 1995.
-
(1995)
Nat. Med.
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
Baylin, S.B.7
Sidransky, D.8
-
12
-
-
0028001087
-
Methylation of the oestrogen receptor CpG island links aging and neoplasia in human colon
-
Issa, J. P., Ottaviano, Y. L., Celano, P., Hamilton, S. R., Davidson, N. E., and Baylin, S. B. Methylation of the oestrogen receptor CpG island links aging and neoplasia in human colon. Nat. Genet., 7:536–540, 1994.
-
(1994)
Nat. Genet.
, vol.7
, pp. 536-540
-
-
Issa, J.P.1
Ottaviano, Y.L.2
Celano, P.3
Hamilton, S.R.4
Davidson, N.E.5
Baylin, S.B.6
-
13
-
-
0028158767
-
Frequent loss of chromosome 9 in human primary non-small cell lung cancer
-
Merlo, A., Gabrielson, E., Askin, F., and Sidransky, D. Frequent loss of chromosome 9 in human primary non-small cell lung cancer. Cancer Res., 54:640–642, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 640-642
-
-
Merlo, A.1
Gabrielson, E.2
Askin, F.3
Sidransky, D.4
-
14
-
-
0026552140
-
Chromosome 3p deletions in head and neck carcinomas:statistical ascertainment of allelic loss
-
Latif, F., Fivash, M., Glenn, G., Tory, K., Orcutt, M. L., Hampsch, K., Delisio, J., Lerman, M., Cowan, J., Beckett, M., and Weichselbaum, R. Chromosome 3p deletions in head and neck carcinomas:statistical ascertainment of allelic loss. Cancer Res., 52:1451–1456, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 1451-1456
-
-
Latif, F.1
Fivash, M.2
Glenn, G.3
Tory, K.4
Orcutt, M.L.5
Hampsch, K.6
Delisio, J.7
Lerman, M.8
Cowan, J.9
Beckett, M.10
Weichselbaum, R.11
-
15
-
-
0022540321
-
CpG-rich islands and the function of DNA methylation
-
Bird, A. P. CpG-rich islands and the function of DNA methylation. Nature (Lond.), 321:209–213, 1986.
-
(1986)
Nature (Lond.)
, vol.321
, pp. 209-213
-
-
Bird, A.P.1
-
16
-
-
84970068204
-
High frequency of homozygous deletion at pl6/CDKN2 in primary human tumors
-
in press
-
Cairns, P., Polascik, T. J., Eby, Y., Tokino, K., Califano, J., Merlo, A., Mao, L., Herath, J., Jenkins, R., Westra, W., Rutter, J. L., Buckler, A., Gavielson, E., Tockman, M., Cho, K. R., Hedrick, L., Bova, G. S., Issacs, W., Schwab, D., and Sidransky, D. High frequency of homozygous deletion at pl6/CDKN2 in primary human tumors. Nat. Genet., in press, 1995.
-
(1995)
Nat. Genet.
-
-
Cairns, P.1
Polascik, T.J.2
Eby, Y.3
Tokino, K.4
Califano, J.5
Merlo, A.6
Mao, L.7
Herath, J.8
Jenkins, R.9
Westra, W.10
Rutter, J.L.11
Buckler, A.12
Gavielson, E.13
Tockman, M.14
Cho, K.R.15
Hedrick, L.16
Bova, G.S.17
Issacs, W.18
Schwab, D.19
Sidransky, D.20
more..
-
17
-
-
0028961521
-
Reciprocal Rb inactivation and pl6INK4 expression in primary lung cancers and cell lines
-
Shapiro, G. I., Edwards, C. D., Kobzik, L., Godleski, J., Richards, W., Sugarbaker, D. J., and Rollins, B. J. Reciprocal Rb inactivation and pl6INK4 expression in primary lung cancers and cell lines. Cancer Res., 55:505–509, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 505-509
-
-
Shapiro, G.I.1
Edwards, C.D.2
Kobzik, L.3
Godleski, J.4
Richards, W.5
Sugarbaker, D.J.6
Rollins, B.J.7
-
18
-
-
0024286232
-
Structural rearrangement of the retinoblastoma gene in human breast carcinoma
-
T'Ang, A., Varley, J. M., Chakraborty, S., Murphree, A. L., and Fung, Y. K. Structural rearrangement of the retinoblastoma gene in human breast carcinoma. Science (Washington DC), 242:263–266, 1988.
-
(1988)
Science (Washington DC)
, vol.242
, pp. 263-266
-
-
T'Ang, A.1
Varley, J.M.2
Chakraborty, S.3
Murphree, A.L.4
Fung, Y.K.5
-
19
-
-
0026697034
-
Abundance and state of phosphorylation of the retinoblastoma susceptibility gene product in human colon cancer
-
Gope, R., and Gope, M. L. Abundance and state of phosphorylation of the retinoblastoma susceptibility gene product in human colon cancer. Mol. Cell. Biochem., 110:123–133, 1992.
-
(1992)
Mol. Cell. Biochem.
, vol.110
, pp. 123-133
-
-
Gope, R.1
Gope, M.L.2
-
20
-
-
0025068887
-
Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene
-
Bookstein, R., Shew, J. Y., Chen, P. L., Scully, P., and Lee, W. H. Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene. Science (Washington DC), 247:712–715, 1990.
-
(1990)
Science (Washington DC)
, vol.247
, pp. 712-715
-
-
Bookstein, R.1
Shew, J.Y.2
Chen, P.L.3
Scully, P.4
Lee, W.H.5
-
21
-
-
0026076091
-
Establishment and characterization of a new human prostatic carcinoma cell line (DuPro-1)
-
Gingrich, J. R., Tucker, J. A., Walther, P. J., Day, J. W., Poulton, S. H. M., and Webb, K. S. Establishment and characterization of a new human prostatic carcinoma cell line (DuPro-1). J. Urol., 246:915–919, 1991.
-
(1991)
J. Urol.
, vol.246
, pp. 915-919
-
-
Gingrich, J.R.1
Tucker, J.A.2
Walther, P.J.3
Day, J.W.4
Poulton, S.H.M.5
Webb, K.S.6
-
22
-
-
0018779369
-
Establishment and characterization of a human prostatic carcinoma cell line (PC-3)
-
Kaighn, M. E., Narayan, K. S., Ohnuki, Y., Lechner, J. F., and Jones, L. W. Establishment and characterization of a human prostatic carcinoma cell line (PC-3). Investigative Urology, 17:16–23, 1979.
-
(1979)
Investigative Urology
, vol.17
, pp. 16-23
-
-
Kaighn, M.E.1
Narayan, K.S.2
Ohnuki, Y.3
Lechner, J.F.4
Jones, L.W.5
-
23
-
-
0023217275
-
Establishment of a new prostatic carcinoma cell line (TSU-PR1)
-
Iizumi, T., Yazaki, T., Kanoh, S., Rondo, I., and Koiso, K. Establishment of a new prostatic carcinoma cell line (TSU-PR1). J. Urol., 137:1304–1306, 1987.
-
(1987)
J. Urol.
, vol.137
, pp. 1304-1306
-
-
Iizumi, T.1
Yazaki, T.2
Kanoh, S.3
Rondo, I.4
Koiso, K.5
-
24
-
-
0018090233
-
Isolation of a human prostate carcinoma cell line (DU 145)
-
Stone, K. R., Mickey, D. D., Wunderli, H., Mickey, G. H., and Paulson, D. F. Isolation of a human prostate carcinoma cell line (DU 145). Int. J. Cancer, 21:274–281, 1978.
-
(1978)
Int. J. Cancer
, vol.21
, pp. 274-281
-
-
Stone, K.R.1
Mickey, D.D.2
Wunderli, H.3
Mickey, G.H.4
Paulson, D.F.5
-
25
-
-
0020638814
-
LNCaP model of human prostatic carcinoma
-
Horoszewicz, J. S., Leong, S. S., Kawinski, E., Karr, J. P., Rosenthal, H., Chu, T. M., Mirand, E. A., and Murphy, G. P. LNCaP model of human prostatic carcinoma. Cancer Res., 43:1809–1818, 1983.
-
(1983)
Cancer Res.
, vol.43
, pp. 1809-1818
-
-
Horoszewicz, J.S.1
Leong, S.S.2
Kawinski, E.3
Karr, J.P.4
Rosenthal, H.5
Chu, T.M.6
Mirand, E.A.7
Murphy, G.P.8
-
26
-
-
0026508613
-
High frequency of somatically acquired p53 mutations in small-cell lung cancer cell lines and tumors
-
D'Amico, D., Carbone, D., Mitsudomi, T., Nau, T., Fedorko, J., Russell, E., Johnson, B., Buchhagen, D., Bodner, S., Phelps, R., Gazdar, A. F., and Minna, J. D. High frequency of somatically acquired p53 mutations in small-cell lung cancer cell lines and tumors. Oncogene, 7:339–346, 1992.
-
(1992)
Oncogene
, vol.7
, pp. 339-346
-
-
D'Amico, D.1
Carbone, D.2
Mitsudomi, T.3
Nau, T.4
Fedorko, J.5
Russell, E.6
Johnson, B.7
Buchhagen, D.8
Bodner, S.9
Phelps, R.10
Gazdar, A.F.11
Minna, J.D.12
-
27
-
-
0028897307
-
Homozygous deletions of the multiple tumor suppressor gene 1 in the progression of human astrocytomas
-
Walker, D. G., Duan, W., Popovic, E. A., Kaye, A. H., Tomlinson, F. H., and Lavin, M. Homozygous deletions of the multiple tumor suppressor gene 1 in the progression of human astrocytomas. Cancer Res., 55:20–23, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 20-23
-
-
Walker, D.G.1
Duan, W.2
Popovic, E.A.3
Kaye, A.H.4
Tomlinson, F.H.5
Lavin, M.6
-
28
-
-
0028987265
-
Mutations in the pl6MK4/MTSl/CDKN2y p!5MK4B/MTS2, and pl8 genes in primary and metastatic lung cancer
-
Okamoto, A., Hussain, S. P., Hagiwara, K., Spillare, E. A., Rusin, M. R., Demetrick, D. J., Serrano, M., Hannon, G. J., Shiseki, M., Zariwala, M., Xiong, Y., Beach, D. H., Yokota, J., and Harris, C. C. Mutations in the pl6MK4/MTSl/CDKN2y p!5MK4B/MTS2, and pl8 genes in primary and metastatic lung cancer. Cancer Res., 55:1448–1451, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 1448-1451
-
-
Okamoto, A.1
Hussain, S.P.2
Hagiwara, K.3
Spillare, E.A.4
Rusin, M.R.5
Demetrick, D.J.6
Serrano, M.7
Hannon, G.J.8
Shiseki, M.9
Zariwala, M.10
Xiong, Y.11
Beach, D.H.12
Yokota, J.13
Harris, C.C.14
-
29
-
-
0028059330
-
Frequent somatic mutations and homozygous deletions of the pl6 (MTS1) gene in pancreatic adenocarcinoma
-
Caldas, C., Hahn, S. A., da Costa, L. T., Redston, M. S., Schutte, M., Seymour, A. B., Weinstein, C. L., Hruban, R. H., Yeo, C. J., and Kern, S. E. Frequent somatic mutations and homozygous deletions of the pl6 (MTS1) gene in pancreatic adenocarcinoma. Nat. Genet., 8:27–32, 1994.
-
(1994)
Nat. Genet.
, vol.8
, pp. 27-32
-
-
Caldas, C.1
Hahn, S.A.2
da Costa, L.T.3
Redston, M.S.4
Schutte, M.5
Seymour, A.B.6
Weinstein, C.L.7
Hruban, R.H.8
Yeo, C.J.9
Kern, S.E.10
-
30
-
-
0028100903
-
Germline pl6 mutations in familial melanoma
-
Hussussian, C. J., Struewing, J. P., Goldstein, A. M., Higgins, P. A., Ally, D. S., Sheahan, M. D., Clark, W. H., Jr., Tucker, M. A., and Dracopoli, N. C. Germline pl6 mutations in familial melanoma. Nat. Genet., 8:15–21, 1994.
-
(1994)
Nat. Genet.
, vol.8
, pp. 15-21
-
-
Hussussian, C.J.1
Struewing, J.P.2
Goldstein, A.M.3
Higgins, P.A.4
Ally, D.S.5
Sheahan, M.D.6
Clark, W.H.7
Tucker, M.A.8
Dracopoli, N.C.9
-
31
-
-
0028875205
-
Methylation fo the 5’ CpG island of the pl6/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
-
Gonzalez-Zulueta, M., Bender, C. M., Yang, A. S., Nguyen, T., Beart, R. W., Van Tornout, J. M., and Jones, P. A., Methylation fo the 5’ CpG island of the pl6/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res., 55:4531–4535, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 4531-4535
-
-
Gonzalez-Zulueta, M.1
Bender, C.M.2
Yang, A.S.3
Nguyen, T.4
Beart, R.W.5
Van Tornout, J.M.6
Jones, P.A.7
|