Does solute stereochemistry influence percutaneous penetration?

Chirality

Volumn 7, Issue 4, 1995, Pages 305-309

  Heard, Charles M ^a   Brain, Keith R ^a,b  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b NONE   (United Kingdom)

Author keywords

ceramide; interaction; keratin; modelling; monolayer; percutaneous penetration; protein binding; skin; stereoselectivity

Indexed keywords

CERAMIDE; EPHEDRINE; INDAPAMIDE; KERATIN; PROPRANOLOL; VERAPAMIL;

ADULT; AGED; ANIMAL CELL; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; DRUG DIFFUSION; DRUG PENETRATION; DRUG STRUCTURE; EPIDERMIS; HUMAN; HUMAN CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SKIN PENETRATION; STEREOCHEMISTRY; STEREOISOMERISM; STRATUM CORNEUM;

CERAMIDES; EPHEDRINE; HUMAN; KERATIN; PROTEIN BINDING; SKIN; SKIN ABSORPTION; STEREOISOMERISM; THERMODYNAMICS;

EID: 0028843878     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.530070419     Document Type: Article

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