OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins

Cell

Volumn 80, Issue 3, 1995, Pages 497-506

  Strubin, Michel ^a   Newell, John W ^b   Matthias, Patrick ^b  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR;

ARTICLE; B LYMPHOCYTE ACTIVATION; CELL SPECIFICITY; CONTROLLED STUDY; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION REGULATION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; LYMPHOBLASTOID CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING;

EID: 0028842156     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(95)90500-6     Document Type: Article

References (58)

1. Oct2 transactivation from a remote enhancer position requires a B-cell-restricted activity
2. Saturation mutagenesis of a yeast his3 “TATA element”: genetic evidence for a specific TATA-binding protein
3. The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains
4. Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival
5. Functional differences between yeast and human TFIID are localized to the highly conserved region
6. The conserved decanucleotide from the immunoglobulin heavy chain promoter induces a very high transcriptional activity in B cells when introduced into a heterologous promoter
7. Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements
8. Targeted disruption of the Oct-2 locus in a B cell provides genetic evidence for two distinct cell type-specific pathways of octamer element-mediated gene activation
9. A novel genetic system to detect protein-protein interactions
10. A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins
11. Cell type-specific elements of the immunoglobulin heavy chain gene enhancer
12. Functional distinctions between yeast TATA elements
13. The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2 and Caenorhabditis elegans unc-86 gene products
14. The p250 subunit of native TATA boxbinding factor TFIID is the cell-cycle regulatory protein CCG1
15. Complex pattern of immunoglobulin μ gene expression in normal and transgenic mice: nonoverlapping regulatory sequences govern distinct tissue specificities
16. The ubiquitous octamer-binding protein(s) is sufficient for transcription of immunoglobulin genes
17. Extinction of an immunoglobulin x promoter in cell hybrids is mediated by the octamer motif and correlates with suppression of Oct-2 expression
18. Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation
19. The octamerbinding proteins form multi-protein: DNA complexes with the HSV α-TIF regulatory protein
20. Cell-cycle regulation of a human histone H2B gene is mediated by the H2B subtype-specific consensus element
21. A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain
22. Octamer-binding proteins from B or HeLa cells stimulate transcription of the immunoglobulin heavy chain promoter in vitro.
23. A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors
24. Transcription cell-type specificity is controlled by an immunoglobulin VH promoter that includes a functional consensus sequence
25. Expression vectors for the analysis of mutant proteins
26. The prolinerich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain
27. Cell-type-specific transcription of an immunoglobulin κ light chain promoter gene in vitro.
28. Expression and activity of the POU transcription factor SCI P
29. A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells
30. Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells
31. Purified octamer binding transcription factors stimulate RNA polymerase III-mediated transcription of the 7SK RNA gene
32. Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation
33. A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells
34. Octamer factors exert a dual effect on the IL-2 and IL-4 promoters
35. Differential transactivation potential of Oct-1 and Oct-2 is determined by additional B cell-specific activities
36. Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cellspecific component for optimal transcription of immunoglobulin promoters
37. Recognition of the surface of a homeo domain protein
38. A simple and highly efficient procedure for rescuing autonomous plasmids from yeast
39. Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation
40. Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro
41. High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier
42. Octamania: the POU factors in murine development
43. Oct-4: a germline-specific transcription factor mapping to the mouse t-complex
44. A nexus between Oct-4 and EIA: implications for gene regulation in embryonic stem cells
45. The human CCG1 gene, essential for progression of the G1 phase, encodes a 210-kilodalton nuclear DNA-binding protein
46. A wide variety of DNA sequences can functionally replace a yeast TATA element for transcriptional activation
47. Immunoglobulin gene transcription
48. A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes
49. The ubiquitous octamerbinding protein Oct-1 contains a POU domain with a homeo box subdomain
50. Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain
51. Coactivators and TAFs: a new class of eukaryotic transcription factors that connect activators to the basal machinery
52. 40
53. POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter
54. Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements
55. The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein
56. An octameroligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity
57. Multiple Oct2 isoforms are generated by alternative splicing