Characterization of the Excitotoxic Potential of the Reversible Succinate Dehydrogenase Inhibitor Malonate

Journal of Neurochemistry

Volumn 64, Issue 1, 1995, Pages 430-436

  Greene, James G ^a   Greenamyre, J Timothy ^a,b,c  

^a Departments of Neurobiology and Anatomy ^*

^b Neurology ^*

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Excitotoxicity; Malonate; Mitochondrion; Neurodegenerative disease; Succinate dehydrogenase

Indexed keywords

6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; 7 CHLOROKYNURENIC ACID; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; DECAHYDRO 6 PHOSPHONOMETHYL 3 ISOQUINOLINECARBOXYLIC ACID; DIZOCILPINE; ENZYME INHIBITOR; KAINIC ACID RECEPTOR; MALONIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SUCCINATE DEHYDROGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; ENZYME INHIBITION; HISTOCHEMISTRY; HYPOTHERMIA; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; STEREOTAXIC SURGERY;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMAL; BODY TEMPERATURE; BRAIN DISEASES; CELL DEATH; CORPUS STRIATUM; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTAMIC ACID; GLYCINE; ISOQUINOLINES; MALE; MALONATES; NEURONS; QUINOXALINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, KAINIC ACID; RECEPTORS, N-METHYL-D-ASPARTATE; SUCCINATE DEHYDROGENASE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

ANIMALIA;

EID: 0028836272     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1995.64010430.x     Document Type: Article

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