Toward a molecular understanding of skeletal development

Cell

Volumn 80, Issue 3, 1995, Pages 371-378

  Erlebacher, Adrian ^a   Filvaroff, Ellen H ^a   Gitelman, Stephen E ^a   Derynck, Rik ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; FIBROBLAST GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA;

BONE DEVELOPMENT; BONE REMODELING; BONE STRUCTURE; CELL DIFFERENTIATION; COLLAGEN SYNTHESIS; ENCHONDRAL OSSIFICATION; HOMEOBOX; HUMAN; MESENCHYME; MOLECULAR BIOLOGY; NONHUMAN; OSTEOCLAST; PRIORITY JOURNAL; REVIEW;

EID: 0028836022     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(95)90487-5     Document Type: Review

References (68)

1. Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation
2. Role of insulin-like growth factors in embryonic and postnatal growth
3. Osteogenesis imperfecta
4. Growth factors and cytokines in bone cell metabolism
5. Transforming growth factor-β gene family members and bone
6. Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs
7. Mice lacking α1(IX) collagen develop noninflammatory degenerative joint disease
8. Life without estrogen
9. Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRYrelated gene
10. Mutation in the COL2A1 gene in a patient with hypochondrogenesis
11. Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest
12. Complexity of FGF receptors: genetic basis for structural diversity and functional specificity
13. c-fos: a key regulator of osteoblast-macrophage lineage determination and bone remodeling
14. The diastrophic dysplasia gene encodes a novel sulfate transporter positional cloning by fine-structure linkage disequilibrium mapping
15. Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein
16. A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis
17. JacksonWeiss and Crouzon syndromes are allelic with mutations in fibroblast growth factor receptor 2
18. Of mice and men: heritable skeletal disorders
19. Transforming growth factor-β and the initiation of chondrogenesis and osteogenesis in rat femur
20. Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene
21. Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage
22. Id gene expression and its suppression by 1,25-dihydroxyvitamin D3 in rat osteoblastic osteosarcoma cells
23. What do BMPs do in mammals? clues from the mouse short-ear mutation
24. The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGFP superfamily
25. Hox genes in vertebrate development
26. Mutations in collagen genes: causes of rare and common diseases in humans
27. Sonic Hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud
28. Osteoporosis induced in mice byoverproduction of interleukin-4
29. A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis
30. Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts
31. Patterns of expression of murine Vgr-1 and BMP-2α suggest that transforming growth factor-β-like genes coordinately regulate aspects of embryonic development
32. The role of homeobox genes in limb development
33. Prediction of bone density from vitamin D receptor alleles
34. A common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer syndrome
35. Expression of helix-loop-helix regulatory genes during differentiation of mouse osteoblastic cells
36. Transient and localized expression of bone morphogenetic protein 4 messenger RNA during fracture healing
37. Osteoarthritis associated with mild chondrodysplasia in transgenic mice expressing al (IX) collagen chains with a central deletion
38. Expression of Id, a negative regulator of helix-loop-helix DNA binding proteins, is down-regulated at confluence and enhanced by dexamethasone in a mouse osteoblastic cell line, MC3T3E1
39. bHLH factors in muscle development: dead lines and commitments, what to leave in and what to leave out
40. Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis
41. Mutations in the fibroblast growth factor receptor 2 gene cause Crouzon syndrome
42. Sonic hedgehog mediates the polarizing activity of the ZPA
43. A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene
44. Gene expression in osteoblastic cells
45. Responsiveness of clonal limb bud cell lines to bone morphogenetic protein 2 reveals a sequential relationship between cartilage and bone cell phenotypes
46. Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia
47. MyoD or Myf-5 is required for the formation of skeletal muscle
48. Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development
49. Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia
50. Molecular to pharmacologic control of osteoblast proliferation and differentiation
51. Estrogen resistance caused by a mutation in the estrogen-receptor gene in man
52. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
53. Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype
54. Limb alterations in brachypodism mice due to mutations in a new member of the TGFβ-superfamily
55. Molecular basis of hereditary disorders of connective tissue
56. Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development
57. Collagen family of proteins
58. Type 11 collagen mutations in rare and common cartilage diseases
59. Autosomal dominant and recessive osteochondrodysplasias associated with the Col11A2 locus
60. Stimulation of the expression of osteogenic and chondrogenic phenotypes in vitro by osteogenin
61. Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9
62. Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse
63. Molecular heterogeneity in osteogenesis Imperfecta type 1
64. The bone morphogenetic protein family and osteogenesis
65. Novel regulators of bone formation: molecular clones and activities
66. Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro
67. Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor
68. The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene