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Volumn 36, Issue 8, 1995, Pages 1267-1270

Selective deprotection of allyl amines using palladium

Author keywords

Allylamines; desallylation; sequential deprotection; allyl palladium methodology

Indexed keywords

AMINE; STYRENE DERIVATIVE;

EID: 0028835937     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(95)00003-U     Document Type: Article
Times cited : (92)

References (12)
  • 10
    • 84914008649 scopus 로고    scopus 로고
    • Genêt, J.P.; Blart, E.; Savignac, M.; Lemaire-Audoire, S. and Bernard, J.M. French patent RP 93039 (june 1993).
  • 11
    • 84914008648 scopus 로고    scopus 로고
    • The proposed mechanism for such efficient desallylation procedure involves a first step of protonation of the allylamine with 2-mercaptobenzoïc acid, followed by rapid equilibrium giving the thiolate which traps the π-allyl palladium intermediate generated in the catalytic cycle.
  • 12
    • 84914008647 scopus 로고    scopus 로고
    • 4 and concentrated in vacuo, affording clean crude products. If necessary, further purification was performed by flash chromatography.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.