-
1
-
-
0027352115
-
Production of 6-APA, 7-ACA and 7-ADCA by immobilized penicillin and cephalosporin amidascs
-
Tanaka, A., Tosa, T. and Kobayashi, T. (Eds.). Marcel Dekker, Inc., NY
-
Matsumoto, K. 1993. Production of 6-APA, 7-ACA and 7-ADCA by immobilized penicillin and cephalosporin amidascs, p. 67-88. In: Industrial Application of Immobilized Biocatalvsts. Tanaka, A., Tosa, T. and Kobayashi, T. (Eds.). Marcel Dekker, Inc., NY.
-
(1993)
Industrial Application of Immobilized Biocatalvsts
, pp. 67-88
-
-
Matsumoto, K.1
-
2
-
-
0025231937
-
Cloning and expression of a hybrid Streptomyces clavuligerus cefEgene in Penicillium chrysogenum
-
Cantwell, C. A., Beckmann, R. J., Dotzlaf, J. E., Fisher, D. L., Skatrud, P. L., Yeh, W-K. and Queener, S. W. 1990. Cloning and expression of a hybrid Streptomyces clavuligerus cefEgene in Penicillium chrysogenum. Curr. Genet. 17:213-221.
-
(1990)
Curr. Genet
, vol.17
, pp. 213-221
-
-
Cantwell, C.1
Beckmann, R.J.2
Dotzlaf, J.E.3
Fisher, D.L.4
Skatrud, P.L.5
Yeh, W.-K.6
Queener, S.W.7
-
3
-
-
0023388057
-
Purification and initial characterization of an enzyme with deacetoxycephalosporin
-
Baldwin, J. E., Adlington, R. M., Coates, J. B., Crabbe, M. J., Crouch, N. P., Keeping, J. W., Knight, G. C, Schofield, C. J., Ting, H-H., Vallejo, C. A., Thorniley, M. and Abraham, E. P. 1987. Purification and initial characterization of an enzyme with deacetoxycephalosporin C synthetase and hydroxylase activities. Biochem. J. 245:831-841.
-
(1987)
C Synthetase and Hydroxylase Activities. Biochem. J
, vol.245
, pp. 831-841
-
-
Baldwin, J.E.1
Adlington, R.M.2
Coates, J.B.3
Crabbe, M.J.4
Crouch, N.P.5
Keeping, J.W.6
Knight, G.C.7
Schofield, C.J.8
Ting, H.-H.9
Vallejo, C.10
Thorniley, M.11
Abraham, E.P.12
-
4
-
-
0024380165
-
Purification and properties of deacetoxy cephalosporin C synthase from recombinant Escherichia coli and its comparison with the native enzyme purified from Streptomyces clavuligerus
-
Dotzlaf, J. E. and Yeh, W-K. 1989. Purification and properties of deacetoxy cephalosporin C synthase from recombinant Escherichia coli and its comparison with the native enzyme purified from Streptomyces clavuligerus. J. Biol. Chem. 264:10219-10227.
-
(1989)
J. Biol. Chem
, vol.264
, pp. 10219-10227
-
-
Dotzlaf, J.E.1
Yeh, W.-K.2
-
5
-
-
0026710635
-
Isolation of deacetoxycephalosporin C from fermentation broths of Penicillium chrysogenum transformants: Construction of a new fungal biosyn-thetic pathway
-
Cantwell, C. A., Beckmann, R., Whiteman, P., Queener, S. W. and Abraham, E. P. 1992. Isolation of deacetoxycephalosporin C from fermentation broths of Penicillium chrysogenum transformants: construction of a new fungal biosyn-thetic pathway. Proc. Royal Soc. London B 238:283-289.
-
(1992)
Proc. Royal Soc. London B
, vol.238
, pp. 283-289
-
-
Cantwell, C.A.1
Beckmann, R.2
Whiteman, P.3
Queener, S.W.4
Abraham, E.P.5
-
6
-
-
0026507004
-
Comparative characterization of new glutaryl 7-ACA and cephalosporin C acylases
-
Aramori, I., Fukagawa, M., Tsumura, M., Iwami, M., Ono, H., Ishitani, Y, Kojo, H., Kohsaka, M., Ueda, Y. and Imanaka, H. 1992. Comparative characterization of new glutaryl 7-ACA and cephalosporin C acylases. J. Ferment. Bioeng. 73:185-192.
-
(1992)
J. Ferment. Bioeng
, vol.73
, pp. 185-192
-
-
Aramori, I.1
Fukagawa, M.2
Tsumura, M.3
Iwami, M.4
Ono, H.5
Ishitani, Y.6
Kojo, H.7
Kohsaka, M.8
Ueda, Y.9
Imanaka, H.10
-
7
-
-
0008413951
-
Incorporation of α,ω-dicarboxylic acids as side-chains into the penicillin molecule
-
Ballio, A., Chain, E. B., di Accadia, F. D., Mastropietro-Cancellieri, M. F., Morpurgo, G., Serlupi-Crescenzi, G. and Sermonti, G. 1960. Incorporation of α,ω-dicarboxylic acids as side-chains into the penicillin molecule. Nature 185:97-99.
-
(1960)
Nature
, vol.185
, pp. 97-99
-
-
Ballio, A.1
Chain, E.B.2
Di Accadia, F.D.3
Mastropietro-Cancellieri, M.F.4
Morpurgo, G.5
Serlupi-Crescenzi, G.6
Sermonti, G.7
-
8
-
-
0000049167
-
The enzymatic ring expansion of penicillins to cephalosporins: Side chain specificity
-
Baldwin, J. E., Adlington, R. M., Crabbe, M. J., Knight, G., Nomoto, T., Schofield, C. J. and Ting, H-H. 1987. The enzymatic ring expansion of penicillins to cephalosporins: side chain specificity. Tetrahedron 43:3009-3014.
-
(1987)
Tetrahedron
, vol.43
, pp. 3009-3014
-
-
Baldwin, J.E.1
Adlington, R.M.2
Crabbe, M.J.3
Knight, G.4
Nomoto, T.5
Schofield, C.J.6
Ting, H.-H.7
-
9
-
-
0020529887
-
Partial purification and properties of the α-ketoglutarate-linked ring-expansion enzyme of /3-lactam biosynthesis of Cephalosporium acremonium
-
Kupka, J., Shen, Y-Q., Wolfe, S. and Demain, A. L. 1983. Partial purification and properties of the α-ketoglutarate-linked ring-expansion enzyme of /3-lactam biosynthesis of Cephalosporium acremonium. FEMS Microbiol. Lett. 16:1-6.
-
(1983)
FEMS Microbiol. Lett
, vol.16
, pp. 1-6
-
-
Kupka, J.1
Shen, Y.-Q.2
Wolfe, S.3
Demain, A.L.4
-
10
-
-
0345690018
-
Biochemical characterization and evolutionary implication of /3-lactam expandase/hydroxylase, expandase and hydroxylase
-
Kleikauf, H. and von Dohren, H. (Eds.). Public, Prague
-
Yeh, W-K., Dotzlaf, J. E. and Huffman, G. W. 1994. Biochemical characterization and evolutionary implication of /3-lactam expandase/hydroxylase, expandase and hydroxylase, p. 208-223. In: 50 Years of Penicillin Application; History and Trends. Kleikauf, H. and von Dohren, H. (Eds.). Public, Prague.
-
(1994)
50 Years of Penicillin Application; History and Trends
, pp. 208-223
-
-
Yeh, W.-K.1
Dotzlaf, J.E.2
Huffman, G.W.3
-
11
-
-
84966141919
-
The substrate specificity of deacetoxycephalosporin C synthase (“expandase”) of Streptomyces clavuligerus is extremely narrow
-
Maeda, K., Luengo, J. M., Ferrero, O., Wolfe, S., Lebedev, M. Y, Fang, A. and Demain, A. L. 1994. The substrate specificity of deacetoxycephalosporin C synthase (“expandase”) of Streptomyces clavuligerus is extremely narrow. Enz. Microb. Technol. In press.
-
(1994)
Enz. Microb. Technol
-
-
Maeda, K.1
Luengo, J.M.2
Ferrero, O.3
Wolfe, S.4
Lebedev, M.Y.5
Fang, A.6
Demain, A.L.7
-
12
-
-
0025103023
-
Cloning of Saccharomyces cerevisiae promoters using a probe vector based on phleomycin resistance
-
Gatignol, A., Dassain, M. and Tiraby, G. 1990. Cloning of Saccharomyces cerevisiae promoters using a probe vector based on phleomycin resistance. Gene 91:35-41.
-
(1990)
Gene
, vol.91
, pp. 35-41
-
-
Gatignol, A.1
Dassain, M.2
Tiraby, G.3
-
13
-
-
0010392177
-
The Panlabs penicillin strain improvement program, p. 105-139
-
Vanek, Z. and Hostalek, Z. (Eds.). Butterworths, Boston
-
Lein, I. 1983. The Panlabs penicillin strain improvement program, p. 105-139. In: Overproduction of Microbial Metabolites. Vanek, Z. and Hostalek, Z. (Eds.). Butterworths, Boston.
-
(1983)
Overproduction of Microbial Metabolites
-
-
Lein, I.1
-
14
-
-
0023585070
-
Cloning and characterization of the genes for two distinct cephalosporin acylases from a Pseudomonas strain
-
Matsuda, A., Matsuyama, K., Yamamoto, K., Ichikawa, S. and Komatsu, K-I. 1987. Cloning and characterization of the genes for two distinct cephalosporin acylases from a Pseudomonas strain. J. Bact. 169:5815-5820.
-
(1987)
J. Bact
, vol.169
, pp. 5815-5820
-
-
Matsuda, A.1
Matsuyama, K.2
Yamamoto, K.3
Ichikawa, S.4
Komatsu, K.-I.5
-
15
-
-
0001235624
-
Isolation and properties of 7/3-(4-carboxybutanamido)cephalosporanic acid acylase-producing bacteria
-
Shibuya, Y., Matsumoto, K. and Fujii, T. 1981. Isolation and properties of 7/3-(4-carboxybutanamido)cephalosporanic acid acylase-producing bacteria. Agrie. Biol. Chem. 45:1561-1567.
-
(1981)
Agrie. Biol. Chem
, vol.45
, pp. 1561-1567
-
-
Shibuya, Y.1
Matsumoto, K.2
Fujii, T.3
-
16
-
-
0023729116
-
Enzymatic synthesis of penicillins
-
Alonso, M. J., Bermejo, F., Reglero, A., Fernandez-Canon, J. M., Gonzalez de Buitrago, G. and Luengo, J. M. 1988. Enzymatic synthesis of penicillins. J. Antibiot. 41:1074-1084.
-
(1988)
J. Antibiot
, vol.41
, pp. 1074-1084
-
-
Alonso, M.J.1
Bermejo, F.2
Reglero, A.3
Fernandez-Canon, J.M.4
Gonzalez De Buitrago, G.5
Luengo, J.M.6
-
17
-
-
0020576474
-
Studies on the ring-cyclization and ring-expansion enzymes of /3-lactam biosynthesis in Cephalosporium acremonium
-
Kupka, J., Shen, Y-Q., Wolfe, S. and Demain, A. L. 1983. Studies on the ring-cyclization and ring-expansion enzymes of /3-lactam biosynthesis in Cephalosporium acremonium. Can. I. Microbiol. 29:488-496.
-
(1983)
Can. I. Microbiol
, vol.29
, pp. 488-496
-
-
Kupka, J.1
Shen, Y.-Q.2
Wolfe, S.3
Demain, A.L.4
-
18
-
-
0026559943
-
Biochemical studies on the activity of δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine synthetase from Streptomyces clavuligerus
-
Zhang, J., Wolfe, S. and Demain, A. L. 1992. Biochemical studies on the activity of δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine synthetase from Streptomyces clavuligerus. Biochem. I. 283:691-698.
-
(1992)
Biochem
, vol.1
, Issue.283
, pp. 691-698
-
-
Zhang, J.1
Wolfe, S.2
Demain, A.L.3
-
19
-
-
0027434537
-
Cloning, characterization, and use in strain improvement of the Cephalosporium acremonium gene cefG encoding acetyl transferase
-
Mathison, L., Soliday, C, Stepan, T., Aldrich, T. and Rambosek, J. 1993. Cloning, characterization, and use in strain improvement of the Cephalosporium acremonium gene cefG encoding acetyl transferase. Curr. Genet. 23:33-41.
-
(1993)
Curr. Genet
, vol.23
, pp. 33-41
-
-
Mathison, L.1
Soliday, C.2
Stepan, T.3
Aldrich, T.4
Rambosek, J.5
-
20
-
-
0026030134
-
Expression of the penDE gene of Pénicillium chrysogenum encoding isopenicillin N acyltransferase in Cephalosporium acremonium: Production of ben-zylpenicillin by the transformants
-
Gutierrez, S., Diez, B., Alvarez, E., Barredo, J. L. and Martin, J. F. 1991. Expression of the penDE gene of Pénicillium chrysogenum encoding isopenicillin N acyltransferase in Cephalosporium acremonium: production of ben-zylpenicillin by the transformants. Mol. Gen. Genet. 225:56-64.
-
(1991)
Mol. Gen. Genet
, vol.225
, pp. 56-64
-
-
Gutierrez, S.1
Diez, B.2
Alvarez, E.3
Barredo, J.L.4
Martin, J.F.5
-
21
-
-
0024565442
-
Amplification of the isopenicillin N synthetase gene in a strain of Pénicillium chrysogenum producing high levels of penicillin
-
Smith, D. J., Bull, J. H., Edwards, J. and Turner, G. 1989. Amplification of the isopenicillin N synthetase gene in a strain of Pénicillium chrysogenum producing high levels of penicillin. Mol. Gen. Genet. 216:492-497.
-
(1989)
Mol. Gen. Genet
, vol.216
, pp. 492-497
-
-
Smith, D.J.1
Bull, J.H.2
Edwards, J.3
Turner, G.4
-
22
-
-
0024811804
-
Large amplification of a 35-kb DNA fragment carrying two penicillin biosynthetic genes in high penicillin producing strains of Penicillium chrysogenum
-
Barredo I.L., Diez, B., Alvarez, E. and Martin, J.F. 1989. Large amplification of a 35-kb DNA fragment carrying two penicillin biosynthetic genes in high penicillin producing strains of Penicillium chrysogenum. Curr. Genet. 16:453459.
-
(1989)
Curr. Genet
, vol.16
, pp. 453-459
-
-
Barredo, I.L.1
Diez, B.2
Alvarez, E.3
Martin, J.F.4
-
23
-
-
0022870031
-
Cloning and expression of the isopenicillin N synthetase gene from Penicillium chrysogenum
-
Carr, L. G.; Skatrud, P. L., Scheetz, M. E., Queener, S. W. and Ingolla, T. D. 1986. Cloning and expression of the isopenicillin N synthetase gene from Penicillium chrysogenum. Gene 48:257-266.
-
(1986)
Gene
, vol.48
, pp. 257-266
-
-
Carr, L.G.1
Skatrud, P.L.2
Scheetz, M.E.3
Queener, S.W.4
Ingolla, T.D.5
-
24
-
-
0024535307
-
Cloning, characterization and expression in Escherichia coli of the Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetase
-
Kovacevik, S., Weigel, B. J., Tobin, M. B., Ingolla, T. D. and Miller, J. R. 1989. Cloning, characterization and expression in Escherichia coli of the Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetase. J. Bact. 171:754-760.
-
(1989)
J. Bact
, vol.171
, pp. 754-760
-
-
Kovacevik, S.1
Weigel, B.J.2
Tobin, M.B.3
Ingolla, T.D.4
Miller, J.R.5
-
25
-
-
0023610319
-
Cloning and expression of the fungal expandase/hydroxylase gene involved in cephalosporin biosynthesis
-
Samson, S. M., Dotzlaf, J. E., Slisz, M. L., Becker, G. W., VanFrank, R. M., Veal, L. E., Yeh, W-K., Miller, I. R., Queener, S. W. and Ingolla, T. D. 1987. Cloning and expression of the fungal expandase/hydroxylase gene involved in cephalosporin biosynthesis. Bio/Technology 5:1207-1214.
-
(1987)
Bio/Technology
, vol.5
, pp. 1207-1214
-
-
Samson, S.M.1
Dotzlaf, J.E.2
Slisz, M.L.3
Becker, G.W.4
Vanfrank, R.M.5
Veal, L.E.6
Yeh, W.-K.7
Miller, I.R.8
Queener, S.W.9
Ingolla, T.D.10
-
26
-
-
0020985635
-
A yeast mitochondrial chelator-sensitive protease that processes cytoplasmically synthesized protein precursors: Isolation from yeast and assay
-
McAda, P. C. and Douglas, M. G. 1983. A yeast mitochondrial chelator-sensitive protease that processes cytoplasmically synthesized protein precursors: isolation from yeast and assay. Methods Enzymol. 97:337-343.
-
(1983)
Methods Enzymol
, vol.97
, pp. 337-343
-
-
McAda, P.C.1
Douglas, M.G.2
-
28
-
-
0026045410
-
Cephalosporin biosynthesis: A branched pathway sensitive to an isotope effect
-
Baldwin, J. E., Adlington, R. M., Crouch, N. P., Schofield, C. J., Turner, N. I. and Aplin, R. T. 1991. Cephalosporin biosynthesis: a branched pathway sensitive to an isotope effect. Tetrahedron 47:9881-9900.
-
(1991)
Tetrahedron
, vol.47
, pp. 9881-9900
-
-
Baldwin, J.E.1
Adlington, R.M.2
Crouch, N.P.3
Schofield, C.J.4
Turner, N.I.5
Aplin, R.T.6
|