Bioactivation of Aromatic Amines by Recombinant Human Cytochrome P4501A2 Expressed in Ames Tester Strain Bacteria: A Substitute for Activation by Mammalian Tissue Preparations

Cancer Research

Volumn 55, Issue 4, 1995, Pages 799-802

  Josephy, P David ^a   DeBruin, Lillian S ^a   Lord, Heather L ^a   Oak, James N ^a   Evans, David H ^a   Guo, Zuyu ^b   Dong, Mi Sook ^b   Guengerich, F Peter ^b  

^a UNIVERSITY OF GUELPH   (Canada)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 3,4 DIMETHYLIMIDAZO[4,5 F]QUINOLINE; 2 AMINOANTHRACENE; 2 FLUORENYLAMINE; ACYLTRANSFERASE; ALPHA NAPHTHOFLAVONE; AROCLOR 1254; AROMATIC AMINE; CYTOCHROME P450 ISOENZYME; RECOMBINANT PROTEIN;

AMES TEST; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; SUPERNATANT;

ACETYLTRANSFERASES; AMINES; BACTERIAL PROTEINS; BIOTRANSFORMATION; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION; GENES, BACTERIAL; HUMAN; MUTAGENICITY TESTS; OXIDOREDUCTASES; RECOMBINANT PROTEINS; SALMONELLA TYPHIMURIUM; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028834113     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

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