The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells

Mutation Research-DNA Repair

Volumn 336, Issue 1, 1995, Pages 69-77

  Collins, Andrew R ^a   Ai guo, Ma ^a   Duthie, Susan J ^a  

^a ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

Comet assay; Deoxyribonucleotide pool; Human cells; Oxidised bases; Strand breaks

Indexed keywords

DEOXYRIBONUCLEOTIDE; HYDROGEN PEROXIDE;

ARTICLE; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; GEL ELECTROPHORESIS; HELA CELL; HUMAN; KINETICS; LYMPHOCYTE; OXIDATION; PRIORITY JOURNAL;

DEOXYRIBONUCLEOSIDES; DNA; DNA DAMAGE; DNA REPAIR; HELA CELLS; HUMAN; HYDROGEN PEROXIDE; LYMPHOCYTES; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; ULTRAVIOLET RAYS;

EID: 0028833163     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/0921-8777(94)00043-6     Document Type: Article

References (19)

1. Chemical carcinogenesis: too many rodent carcinogens
2. The data support a role for antioxidants in reducing cancer risk
3. Quiescent human peripheral blood lymphocytes do not contain a sizable amount of preexistent DNA single-strand breaks
4. Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA
5. Review of repair kinetics for DNA damage induced in eukaryotic cells in vitro by ionizing radiation
6. Single-cell gel electrophoresis applied to the analysis of UV-C damage and its repair in human cells
7. The effect of deoxynucleosides on repair of DNA breaks in UVC-irradiated human lymphocytes
8. DNA damage and oxygen radical toxicity
9. Role of DNA breaks and DAP-ribosyl transferase activity in eukaryotic differentiation demonstrated in human lymphocytes
10. Quiescent human lymphocytes do not contain DNA strand breaks detectable by alkaline elution
11. Repair of DNA damage induced by oxygen radicals in human non-proliferating and proliferating lymphocytes
12. Instability and decay of the primary structure of DNA
13. The deoxyribonucleoside 5′-triphosphate (dATP and dTTP) pool in phytohemagglutinin-stimulated and non-stimulated human lymphocytes
14. Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the ‘comet’ assay
15. Animal cell DNA polymerases in DNA repair
16. Oxidant-induced DNA damage of target cells
17. A simple technique for quantitation of low levels of DNA damage in individual cells
18. Induction and repair of DNA single-strand breaks and DNA base damage at different stages of spermatogenesis of the hamster upon in vitro exposure to ionizing radiation