Protein kinases in the locus coeruleus and periaqueductal gray matter are involved in the expression of opiate withdrawal

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 352, Issue 5, 1995, Pages 565-575

  Maldonado, Rafael ^a   Valverde, Olga ^a   Garbay, Christiane ^a   Roques, Bernard P ^a  

^a Laboratoire de Pharmacochimie   (France)

Author keywords

Locus coeruleus; Morphine withdrawal; Naloxone; Periaqueductal gray matter; Protein kinases; Serine threonine kinase inhibitor; Tyrosine kinase inhibitor

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 5 [(2,5 DIHYDROXYBENZYL)AMINO] 2 HYDROXYBENZOIC ACID 3 PHENYLPROPYL ESTER; ISOENZYME; KB 23; MORPHINE; NALOXONE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PROTEIN SERINE KINASE; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DRUG ANTAGONISM; HISTOLOGY; HYPERACTIVITY; INTRACEREBRAL DRUG ADMINISTRATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; JUMPING; LOCUS CERULEUS; MALE; MORPHINE ADDICTION; MOTOR ACTIVITY; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; RAT; WITHDRAWAL SYNDROME;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; AMINOSALICYLIC ACIDS; ANIMAL; ENZYME INHIBITORS; ISOQUINOLINES; LOCUS COERULEUS; MALE; MORPHINE; NALOXONE; PIPERAZINES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASE; RATS; RATS, WISTAR; SUBSTANCE WITHDRAWAL SYNDROME; SUPPORT, NON-U.S. GOV'T;

EID: 0028829387     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/BF00169392     Document Type: Article

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