Negative feedback regulation and desensitization of insulin-and epidermal growth factor-stimulated p21ras activation

Journal of Biological Chemistry

Volumn 270, Issue 43, 1995, Pages 25320-25323

  Langlois, W John ^a,b   Sasaoka, Toshiyasu ^c   Saltiel, Alan R ^d   Olefsky, Jerrold M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^c UNIVERSITY OF TOYAMA   (Japan)

^d PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; EPIDERMAL GROWTH FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; INSULIN; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PROTEIN P21; RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DESENSITIZATION; DISSOCIATION; ENZYME INHIBITION; FEEDBACK SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

ANIMAL; BLOTTING, WESTERN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; DOWN-REGULATION; EPIDERMAL GROWTH FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTORS; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HUMAN; INSULIN; PRECIPITIN TESTS; PROTEINS; PROTO-ONCOGENE PROTEIN P21(RAS); RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS; RATS; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028829346     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.270.43.25320     Document Type: Article

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