Transfer of a mutated gene encoding active transforming growth factor-β1 suppresses mitogenesis and IL-1 response in the glomerulus

Kidney International

Volumn 48, Issue 6, 1995, Pages 1747-1757

  Kitamura, Masanori ^a   Burton, Stephen ^b   English, Jennifer ^b   Kawachi, Hiroshi ^b   Fine, Leon G ^b  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 1BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; GENE TRANSFER; GLOMERULUS; IN VITRO STUDY; MESANGIUM CELL; MITOGENESIS; MITOSIS INHIBITION; NEPHRITIS; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0028827488     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1995.473     Document Type: Article

References (61)

1. BORDER WA, RUOSLAHTI E: Transfroming growth factor-β in disease: The dark side of tissue repair. J Clin Invest 90:1-7, 1992
2. DE MARTIN R, HAENDLER B, HOFER-WARBINEK R, GAUGITSH H, WRANN M, SCHLUSENER H, SEIFERT JM, BODMER S, FONTANA A, HOFER E: Complementary DNA for human gliohlastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-β gene family. EMBO J 6:3673-3677, 1987
3. WAHL SM, HUNT DA, WAKEFIELD LM, MCCARTNEY-FRANCIS N, WAHL LM, ROBERTS AB, SPORN MB: Transforming growth factor type β induces monocyte chemotaxis and growth factor production. Proc Natl Acad Sci USA 84:5788-5792, 1987
4. TSUNAWAKI S, SPORN MB, DING A, NATHAN C: Deactivation of macrophages by transforming growth factor-β. Nature 334:260-262, 1988
5. MAIN IW, NIKOLIC-PATERSON DJ, ATKINS RC: T cells and macrophages and their role in renal injury. Semin Nephrol 12:395-407, 1992
6. LEFER AM: Mechanisms of the protective effects of transforming growth factor-β in reperfusion injury. Biochem Pharmacol 42:1323-1327, 1991
7. REDINI F, MAUVIEL A, PRONOST S, LOYAU G, PUJOL J-P: Transforming growth factor-β exerts opposite effects from interleukin-1β on cultured rabbit articular chondrocytes through reduction of interleukin-1 receptor expression. Arthr Rheum 36:44-50, 1993
8. VAN BEUNINGEN HM, VAN DER KRAAN PM, ARNTZ OJ, VAN DEN BERG WB: Protection from interleukin-1 induced destruction of articular cartilage by transforming growth factor-β: Studies in anatomically intact cartilage in vitro and in vivo. Ann Rheum Dis 52:185-191, 1993
9. PFEILSCHIFTER J, VOSBECK K: Transforming growth factor β2 inhibits interleukin 1β- and tumour necrosis factor α-induction of nitric oxide synthase in rat renal mesangial cells. Biochem Biophys Res Commun 175:372-379, 1991
10. MASSAGUE J: The transforming growth factor-β family. Annu Rev Cell Biol 6:597-641, 1990
11. STRIKER LJ, PETEN EP, ELLIOT SJ, DOI T, STRIKER GE: Mesangial cell turnover: Effect of heparin and peptide growth factors. Lab Invest 64:446-456, 1991
12. - antiport activity. Proc Natl Acad Sci USA 82:6163-6166, 1985
13. BORDER WA, OKUDA S, LANGUINO LR, SPORN MB, RUOSLAHTI E: Suppression of experimental glomerulonephritis by anti-serum against transforming growth factor β1. Nature 346:371-374, 1990
14. OKUDA S, LANGUINO LR, RUOSLAHTI E, BORDER WA: Elevated expression of transforming growth factor-β and proteoglycan production in experimental glomerulonephritis. J Clin Invest 86:453-462, 1990
15. BORDER WA, NOBLE NA, YAMAMOTO T, HARPER JR, YAMAGUCHI Y, PIERSCHBACHER MD, RUOSLAHTI E: Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease. Nature 360:361-364, 1992
16. ISAKA Y, FUJIWARA Y, UEDA N, KANEDA Y, KAMADA T, IMAI E: Glomerulosclerosis induced by in vivo transfection of transforming growth factor-β or platelet-derived growth factor gene into the rat kidney. J Clin Invest 92:2597-2601, 1993
17. KITAMURA M, TAYLOR S, UNWIN R, BURTON S, SHIMIZU F, FINE LG: Gene transfer into the rat renal glomerulus via a mesangial cell vector: Site-specific delivery, in situ amplification, and sustained expression of an exogenous gene in vivo. J Clin Invest 94:497-505, 1994
18. SAMUEL SK, HURTA RAR, KONDAIAH P, KHALIL N, TURLEY EA, WRIGHT JA, GREENBERG AH: Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-β1 (Ser223, 225). EMBO J 11:1599-1605, 1992
19. GUNNING P, LEAVITT J, MUSCAT G, NG S-Y, KEDES L: A human β-actin expression vector system directs high-level accumulation of anti-sense transcripts. Proc Natl Acad Sci USA 84:4831-4835, 1987
20. KITAMURA M, MITARAI T, MARUYAMA N, NAGASAWA R, YOSHIDA H, SAKAI O: Mesangial cell behavior in a three-dimensional extracellular matrix. Kidney Int 40:653-661, 1991
21. CHEN C, OKAYAMA H: High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 7:2745-2752, 1987
22. KITAMURA M, SHIRASAWA T, MARUYAMA N: Gene transfer of metalloproteinase transin induces aberrant behavior of cultured mesangial cells. Kidney Int 45:1580-1586, 1994
23. KITAMURA M, SHIRASAWA T, MITARAI T, MURAMATSU T, MARUYAMA N: A retinoid responsive cytokine gene, MK, is preferentially expressed in the proximal tubules of the kidney and human tumor cell lines. Am J Pathol 142:425-431, 1993
24. TANAKA H, HOJO K, YOSHIDA H, YOSHIOKA T, SUGITA K: Molecular cloning and expression of the mouse 105-kDa gelatinase cDNA. Biochem Biophys Res Commun 190:732-740, 1993
25. KITAMURA M, MARUYAMA N, SHIRASAWA T, NAGASAWA R, WATANABE K, TATENO M, YOSHIKI T: Expression of an endogenous retroviral gene product in human placenta. Int J Cancer 58:836-840, 1994
26. CONE JL, BROWN DR, DELARCO JE: Improved method of purification of transforming growth factor, type β from platelets. Anal Biochem 168:71-74, 1988
27. YOKOO T, KITAMURA M: Dual regulation of IL-1β-mediated matrix metalloproteinase-9 expression in mesangial cells by NF-κB and AP-1. Am J Physiol (in press)
28. BROWN PD, LEVY IT, MARGULIES IMK, LIOTTA LA, STETLER-STEVENSON WG: Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines. Cancer Res 50:6184-6191, 1990
29. KAWACHI H, ORISAKA M, MATSUI K, IWANAGA T, TOYABE S, OITE T, SHIMIZU F: Epitope-specific induction of mesangial lesions with proteinuria by a MoAb against mesangial cell surface antigen. Clin Exp Immunol 88:399-404, 1992
30. KANAME S, UCHIDA S, OGATA E, KUROKAWA K: Autocrine secretion of transforming growth factor-β in cultured rat mesangial cells. Kidney Int 42:1319-1327, 1992
31. LYONS RM, KESKI-OJA J, MOSES HL: Proteolytic activation of latent transforming growth factor-β from fibroblast-conditioned medium. J Cell Biol 106:1659-1655, 1988
32. DUBOIS CM, RUSCETTI FW, PALASZYNSKI EW, FALK LA, OPPENHEIM JJ, KELLER JR: Transforming growth factor β is a potent inhibitor of IL-1 receptor expression: Proposed mechanism of inhibition on IL-1 action. J Exp Med 172:737-744, 1990
33. SEDOR JR, NAKAZATO Y, KONIECZKOWSKI M: Interleukin-1 and the mesangial cell. Kidney Int 41:595-599, 1992
34. MACKAY K, STRIKER LJ, STAUFFER JW, DOI T, AGODOA LY, STRIKER GE: Transforming growth factor-β: Murine glomerular receptors and responses of isolated glomerular cells. J Clin Invest 83:1160-1167, 1989
35. JAFFER F, SAUNDERS C, SCHULTZ P, THROCKMORTON D, WEINSHELL E, ABBOUD HE: Regulation of mesangial cell growth by polypeptide mitogens. Inhibitory role of transforming growth factor beta. Am J Pathol 135:261-269, 1989
36. NAKAMURA T, MILLER D, RUOSLAHTI E, BORDER WA: Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-β1. Kidney Int 41:1213-1221, 1992
37. CHOI ME, BALLERMANN BJ: A transdominant negative mutant TGF-β type II receptor inhibits capillary morphogenesis and associated apoptosis. (abstract) J Am Soc Nephrol 5:690, 1994
38. DERYNCK R: TGF-β-receptor-mediated signaling. Tred Biochem Sci 19:548-553, 1994
39. ROBERTS AB, ANZANO MA, WAKEFIELD LM, ROCHE NS, STERN DF, SPORN MB: Type β transforming growth factor: A bifunctional regulator of cellular growth. Proc Natl Acad Sci USA 82:119-123, 1985
40. YAMAMOTO T, WILSON CB: Quantitative and qualitative studies of antibody-induced mesangial cell damage in the rat. Kidney Int 32:514-525, 1987
41. VAN DIEMEN-STEENVOORDE R, LAMBERS A, VAN DER WAL A, VAN ROOYEN N, DIJKSTRS C, HOEDEMAEKER PJ, DE HEER E: Macrophages are responsible for mesangial cell injury and extracellulat matrix expansion in anti-Thy-1 nephritis in rats, (abstract) J Am Soc Nephrol 2:585, 1991
42. DING A, NATHAN CF, GRAYCAR J, DERYNCK R, STUEHR DJ, SRIMAL S: Macrophage deactivating factor and transforming growth factors-β1, -β2, and -β3 inhibit induction of macrophage nitrogen oxide synthesis by IFN-γ. J Immunol 145:940-944, 1990
43. ESPEVIK T, FIGARI IS, SHALABY MR, LACKIDES GA, LEWIS GA, SHEPARD HM, PALLADINO MA: Inhibition of cytokine production by cyclosporin A and transforming growth factor β. J Exp Med 166:571-576, 1987
44. MENE P, SIMONSON MS, DUNN MJ: Physiology of the mesangial cell. Physiol Rev 69:1347-1424, 1989
45. DINARELLO CA: Inflammatory cytokines: Interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases. Curr Opin Immunol 3:941-948, 1991
46. SEDOR JR: Cytokines and growth factors in renal injury. Semin Nephrol 12:428-440, 1992
47. TANG WW, FENG L, VANNICE JL, WILSON CB: Interleukin-1 receptor antagonist ameliorates experimental anti-glomerular basement membrane antibody-associated glomerulonephritis. J Clin Invest 93:273-279, 1994
48. LAN HY, NIKOLIC-PATERSON DJ, ZARAMA M, VANNICE JL, ATKINS RC: Suppression of experimental crescentic glomerulonephritis by the interleukin-1 receptor antagonist. Kidney Int 43:479-485, 1993
49. PFEILSCHIFTER J, SCHWARTZENBACH H: Interleukin 1 and tumor necrosis factor stimulate cGMP formation in rat renal mesangial cells. FEBS Lett 273:185-187, 1990
50. ZOJA C, WANG JM, BETTONI S, SIRONI M, RENZI D, CHIAFFARINO F, ABBOUD HE, DAMME JV, MANTOVANI A, REMUZZI G, RAMBALDI A: Interleukin-1β and tumor necrosis factor-α induce gene expression and production of leukocyte chemotactic factors, colony-stimulating factors, and interleukin-6 in human mesangial cells. Am J Pathol 138:991-1003, 1991
51. RUSCETTI FW, DUBOIS CM, JACOBSEN SEW, KELLER JR: Transforming growth factor β and interleukin-1: A paradigm for opposing regulation of haemopoiesis. Bailliere's Clin Haematol 5:703-721, 1992
52. NAKAGAWA Y, KURODA T, NARITA I, KIMURA H, TAKEDA T, MEGURO H, YAMAZAKI H, SAKATSUME M, SHIMADA H, UENO M, ARAKAWA M: Decorin suppresses TGF-β mRNA expression in rat anti-GBM nephritis, (abstract) J Am Soc Nephrol 5:698, 1994
53. MARTI HP, LEE L, KASHGARIAN K, LOVETT DH: Transforming growth factor-β1 stimulates glomerular mesangial cell synthesis of 72-kd type IV collagenase. Am J Pathol 144:82-94, 1994
54. BORDER WA, NOBLE NA: Transforming growth factor β in tissue fibrosis. N Engl J Med 331:1286-1292, 1994
55. WAHL SM, MCCARTNEY-FRANCIS N, MERGENHAGEN SE: Inflammatory and immunomodulatory roles of TGF-β. Immunol Today 10:258-261, 1989
56. MACKAY K, KONDAIAH P, DANIELPOUR D, AUSTIN HA III, BROWN PD: Expression of transforming growth factor-β1 and β2 in rat glomeruli. Kidney Int 38:1095-1100, 1990
57. ANDO T, OKUDA S, TAMAKI K, YOSHITOMI K, FUJISHIMA M: Localization of transforming growth factor-β and latent transforming growth factor-β binding protein in rat kidney. Kidney Int 47:733-739, 1995
58. SHULL MM, ORMSBY I, KIER AB, PAWLOWSKI S, DIEBOLD RJ, YIN M, ALLEN R, SIDMAN C, PROETZEL G, CALVIN D, ANNUZIATA N, DOETSCHMAN T: Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease. Nature 359:693-699, 1992
59. BRANDES ME, ALLEN JB, OGAWA Y, WAHL SM: Transforming growth factor-β1 suppresses acute and chronic arthritis in experimental animals. J Clin Invest 87:1108-1113, 1991
60. KURUVILLA AP, SHAH R, HOCHWALD GM, LIGGITT HD, PALLADINO MA, THORBECKE GJ: Protective effect of transforming growth factor-β1 on experimental autoimmune diseases in mice. Proc Natl Acad Sci USA 88:2918-2921, 1991
61. PANKEWYCZ OG, GUAN JX, TREVELDI E: Early therapy of NOD mice with transforming growth factor β2 diminishes insulitis and reduces the incidence of diabetes. (abstract) J Am Soc Nephrol 5:761, 1994