SCOPUS 정보 검색 플랫폼

Volumn 36, Issue 43, 1995, Pages 7819-7822

A solid phase protocol of the biginelli dihydropyrimidine synthesis suitable for combinatorial chemistry

Author keywords

[No Author keywords available]

Indexed keywords

PYRIMIDINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; METHODOLOGY; REACTION ANALYSIS;

EID: 0028827034 PISSN: 00404039 EISSN: None Source Type: Journal
DOI: 10.1016/0040-4039(95)01660-A Document Type: Article

Times cited : (316)

References (13)

1
- 84915386958
- Eli Lilly Grantee, 1993–95; Alfred P. Sloan Research Fellow, 1994–96; NSF Presidential Faculty Fellow, 1994–99; Camille Dreyfus Teacher-Scholar, 1995–97.

2
- 0028243847
- For excellent reviews covering the history of this technique as well as recent developments, see
- (1994) J. Med. Chem. , vol.37 , pp. 1233
- Gallop¹ Barrett² Dower³ Fodor⁴ Gordon⁵

3
- 0028318863
- For excellent reviews covering the history of this technique as well as recent developments, see
- (1994) J. Med. Chem. , vol.37 , pp. 1385
- Gordon¹ Barrett² Dower³ Fodor⁴ Gallop⁵

4
- 33748223166
- The Seven-Component Reaction**
- (1993) Angewandte Chemie International Edition in English , vol.32 , pp. 563
- Dömling¹ Ugi²

6
- 0027205552
- references cited therein.
- (1993) Tetrahedron , vol.49 , pp. 6937
- Kappe¹

10
- 33845557921
- (1981) J. Org. Chem. , vol.46 , pp. 3433
- Lu¹ Mojsov² Tam³ Merrifield⁴

11
- 0001723969
- 2O/THF according to
- (1987) Tetrahedron , vol.43 , pp. 891
- Viret¹ Gabard² Collet³

12
- 84915386957
- 2. This cleavage led to 6.05 mg of 4-ureidobutyric acid (98% yield). General procedure for solution Biginelli reactions: A solution of 100 mg (0.42 mmol) 4-ureidobutyric acid benzyl ester (12) in 2 mL of THF was treated with 2 eq (0.84 mmol) of aldehyde and 2 eq (0.84 mmol) of β-ketoester. The solution was stirred for 5 min at room temperature, and [[Truncated]]

13
- 33847805890
- Alkylation of dianions of .beta.-keto esters
- (1974) Journal of the American Chemical Society , vol.96 , pp. 1082
- Weiler¹

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.