A New Paclitaxel Photoaffinity Analog with a 3-(4-Benzoylphenyl)propanoyl Probe for Characterization of Drug-Binding Sites on Tubulin and P-Glycoprotein

Journal of Medicinal Chemistry

Volumn 38, Issue 20, 1995, Pages 3891-3894

  Ojima, Iwao ^a   Duclos, Olivier ^a   Dormán, György ^a   Simonot, Bruno ^a   Prestwich, Glenn D ^a   Rao, Srinivasa ^b   Lerro, Keith A ^b   Horwitz, Susan B ^b  

^a STONY BROOK UNIVERSITY   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3' N [3 (4 BENZOYLPHENYL)PROPIONYL] 3' N DEBENZOYLPACLITAXEL; BACCATIN III; GLYCOPROTEIN P; PACLITAXEL DERIVATIVE; TRIETHYLAMINE; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG SENSITIVITY; DRUG SYNTHESIS; MICROTUBULE ASSEMBLY; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PHOTOAFFINITY LABELING;

AFFINITY LABELS; ANIMAL; ANTINEOPLASTIC AGENTS; BINDING SITES; MICE; P-GLYCOPROTEIN; PACLITAXEL; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TUBULIN;

EID: 0028825869     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00020a001     Document Type: Article

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