Quantitative relationship between brain temperature and energy utilization rate measured in Vivo using 31P and 1H magnetic resonance spectroscopy

Pediatric Research

Volumn 38, Issue 6, 1995, Pages 919-925

  Laptook, Abbot R ^a   Corbett, Ronald J T ^a   Sterett, Rick ^b   Garcia, Damian ^a   Tollefsbol, Greg ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b University Medical Center of Southern Nevada   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; BRAIN PROTECTION; BRAIN TEMPERATURE; CONTROLLED STUDY; ENERGY METABOLISM; HEART ARREST; HYPOTHERMIA; HYPOXIA; IN VIVO STUDY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; SWINE;

ADENOSINE TRIPHOSPHATE; ANIMAL; BODY TEMPERATURE REGULATION; BRAIN; BRAIN ISCHEMIA; ENERGY METABOLISM; LINEAR MODELS; MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHORUS; PROTONS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; SWINE;

EID: 0028825412     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1203/00006450-199512000-00015     Document Type: Article

References (30)

1. Laptook AR, Corbett RJT, Sterett R, Burns DK, Tollefsbol G, Garcia D 1994 Modest hypothermia provides partial neuroprotection for ischemic neonatal brain. Pediatr Res 35:436-442
2. Ikonomidou C, Mosinger JL, Olney JW 1989 Hypothermia enhances protective effects of MK801 against hypoxic-ischemic brain damage in infant rats. Brain Res 487:184-187
3. Yager J, Towfighi J, Vannucci RC 1993 Influence of mild hypothermia on hypoxic-ischemic brain damage in the immature rat. Pediatr Res 34:525-529
4. Laptook AR, Corbett RJT, Sterett R, Burns D, Tollefsbol G, Garcia D 1993 A potential mechanism for ischemic neuroprotection by modest hypothermia: attenuation of brain acidosis. Proc Soc Magn Reson Med 1:520
5. Busto R, Globus MYT, Dietrich D, Martinez E, Valdes I, Ginsberg MD 1989 Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain. Stroke 20:904-910
6. Stacker F, Herschkowitz N, Bossi E, Stoller M, Cross TA, Aue WP, Seelig J 1986 Cerebral metabolic studies in situ by 3IP nuclear magnetic resonance after hypothermic circulatory arrest. Pediatr Res 20:867-871
7. Young RSK, Olenginski TP, Yagel SK, Towfighi J 1983 The effect of graded hypothermia on hypoxic-ischemic brain damage: a neuropathologic study in the neonatal rat. Stroke 14:929-934
8. Chopp M, Knight R, Tidewell CD, Helpern JA, Brown E, Welch KMA 1989 The metabolic effects of mild hypothermia on global cerebral ischemia and recirculation in the cat: comparison to normothermia and hyperthermia. J Cereb Blood Flow Metab 9:141-148
9. Sutherland GR, Lesiuk H, Hazendonk P, Peeling J, Buist R, Kozlowski P, Jazinski A, Saunders JK 1992 Magnetic resonance imaging and 31P magnetic resonance spectroscopy study of the effect of temperature on ischemic brain injury. Can J Neurol Sci 19:317-325
10. Corbett RJT, Laptook AR, Garcia D, Ruley JI 1993 Energy reserves and utilization rates in developing brain measured in vivo by 3, P and H nuclear magnetic resonance spectroscopy. J Cereb Blood Flow Metab 13:235-246
11. Linderkamp O, Betke K, Gunter M, Jap GH, Riegel KP, Walser K 1981 Blood volume newborn piglets: effects of time of natural cord rupture, intrauterine growth retardation, asphyxia, and prostaglandin-induced prematurity. Pediatr Res 15:53-57
12. Laptook AR, Corbett RJT, Nguyen HT, Peterson J, Nunnally RL 1988 Alterations in cerebral blood flow and phosphorylated metabolites in piglets during and after partial ischemia. Pediatr Res 23:206-211
13. Gonnella NC, Silver RF 1989 Design and construction of a simple double tuned single input surface coil probe. J Magn Reson 85:24-34
14. Hore PJ 1983 Solvent suppression of Fourier transform nuclear magnetic resonance. J Magn Reson 55:283-300
15. Corbett RJT, Laptook AR, Nunnally RL, Hassan A, Jackson J 1988 Intracellular pH, lactate and energy metabolism in neonatal brain during partial ischemia measured in vivo by 31P and JH nuclear magnetic resonance spectroscopy. J Neurochem 51:1501-1509
16. Frost AA, Pearson RG 1961 In Kinetics and Metabolism. John Wiley & Sons, New York, pp 27-55
17. Chessex P, Reichman BL, Verellen GJE, Putet G, Smith JM, Hein T, Swyer PR 1981 Relation between heart rate and energy expenditure in the newborn. Pediatr Res 15:1077-1082
18. Hagerdal M, Harp J, Siesjo BK 1975 Effect of hypothermia upon organic phosphates, glycolytic metabolites, citric acid cycle intermediates and associated amino acids in rat cerebral cortex. J Neurochem 24:743-748
19. Johnson DC, Nishimura M, Okunieff P, Kazemi H, Hitzig B 1989 Effects of hypothermia on rat brain pHi and phosphate metabolite regulation by 3IP-NMR. J Appl Physiol 67:2527-2534
20. Aoki M, Nomura F, Stromski ME, Tsuji MK, Fackler JC, Hickley PR, Holtzman DH, Jonas RA 1993 Effects of pH on brain energetics after hypothermic circulatory arrest. Ann Thorac Surg 55:1093-1103
21. Petroff OAC, Prichard JW, Ogino T, Shulman RG 1988 Proton magnetic resonance spectroscopic studies of agonal carbohydrate metabolism in rabbit brain. Neurology 38:1569-1574
22. Norwood WI, Norwood CR, Ingwall JS, Castaneda AR, Fossel ET 1979 Hypothermic circulatory arrest: 31P phosphorus nuclear magnetic resonance of isolated perfused neonatal rat brain. J Thorac Cardiovasc Surg 78:823-830
23. Kramer RS, Sanders AP, Lesage AM, Woodhall B, Sealy WC 1968 The effect of profound hypothermia on preservation of cerebral ATP content during circulatory arrest. J Thorac Cardiovasc Surg 56:699-709
24. Greeley WJ, Kern FH, Ungerleider RM, Boyd JL, Quill T, Smith LR, Baldwin B, Reves JG 1991 The effect of hypothermic cardiopulmonary bypass and total circulatory arrest on cerebral metabolism in neonates, infants and children. J Thorac Cardiovasc Surg 101:783-794
25. Hagerdal M, Harp J, Nilsson L, Siesjo BK 1975 The effect of induced hypothermia upon oxygen consumption in the rat brain. J Neurochem 24:311-316
26. Michenfelder JD, Milde JH 1991 The relationship among canine brain temperature, metabolism, and function during hypothermia. Anesthesiology 75:130-136
27. Carlsson C, Hagerdal M, Siesjo BK 1976 The effect of hyperthermia upon oxygen consumption and upon organic phosphates, glycolytic metabolites, citric acid cycle intermediates and associated amino acids in rat cerebral cortex. J Neurochem 26:1001-1006
28. Astrup J, Moller-Sorenson P, Rahbeck-Sorenson H 1981 Inhibition of cerebral oxygen and glucose consumption in the dog by hypothermia, pentobarbital and lidocaine. Anesthesiology 55:263-268
29. Siesjo BK, Bengtson F 1989 Calcium fluxes, calcium antagonists and calcium related pathology in brain ischemia, hypoglycemia and spreading depression. A unifying hypothesis. J Cereb Blood Flow Metab 9:127-140
30. Berntman L, Welsh FA, Harp JR 1981 Cerebral protective effect of low-grade hypothermia. Anesthesiology 55:495-498