Differentiation between partial and silent 5-HT1dβ receptor antagonists using rat C6-glial and chinese hamster ovary cell lines permanently transfected with a cloned human 5-HT1dβ receptor gene

Biochemical Pharmacology

Volumn 50, Issue 10, 1995, Pages 1651-1658

  Pauwels, Petrus J ^a   Colpaert, Francis C ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

agonist partial agonist antagonist; cloned human 5 HT1D receptor; intrinsic activity; permanent cell transfection

Indexed keywords

1 (3 TRIFLUOROMETHYLPHENYL)PIPERAZINE; 1 NAPHTHYLPIPERAZINE; 4 (4 METHYL 1 PIPERAZINYL) 7 TRIFLUOROMETHYLPYRROLO[1,2 A]QUINOXALINE; 5 CARBAMOYLTRYPTAMINE; 5 METHOXY 3 (1,2,3,6 TETRAHYDRO 4 PYRIDYL) 1H INDOLE; 5 METHOXYTRYPTAMINE; BUFOTENINE; CYCLIC AMP; FORSKOLIN; METERGOLINE; METITEPINE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; PARTIAL AGONIST; RADIOLIGAND; RECEPTOR SUBTYPE; RITANSERIN; SEROTONIN; SEROTONIN 1D RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR AFFECTING AGENT; SUMATRIPTAN; TRYPTAMINE; UNCLASSIFIED DRUG;

AGONIST; ANIMAL CELL; ARTICLE; CELL CULTURE; CHO CELL; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG POTENCY; GENETIC TRANSFECTION; GLIA CELL; HUMAN; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; RECEPTOR INTRINSIC ACTIVITY;

ANIMAL; CELL LINE; CHO CELLS; CLONING, MOLECULAR; CYCLIC AMP; HAMSTERS; HUMAN; KINETICS; LIGANDS; NEUROGLIA; RADIOLIGAND ASSAY; RATS; RECEPTORS, SEROTONIN; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; STIMULATION, CHEMICAL; TRANSFECTION;

EID: 0028825191     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(95)02059-4     Document Type: Article

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